日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Atezolizumab plus FOLFOX for Stage III Mismatch Repair-Deficient Colon Cancer

阿特珠单抗联合FOLFOX方案治疗III期错配修复缺陷型结肠癌

Sinicrope, Frank A; Ou, Fang-Shu; Arnold, Dirk; Peters, Walter R; Behrens, Robert J; Lieu, Christopher H; Matin, Khalid; Cohen, Deirdre J; Potter, Samara L; Nixon, Andrew B; Kottschade, Lisa A; Kathol, Emily; Frankel, Wendy L; Shergill, Ardaman; Hsu, Dennis; Reinacher-Schick, Anke; Mehan, Paul; Gold, Philip J; Khalil, Maged F; Zemla, Tyler; Gatten, Clare; O'Reilly, Eileen M; Meyerhardt, Jeffrey A

Tissue-Free Circulating Tumor DNA Assay and Patient Outcome in a Phase III Trial of FOLFOX-Based Adjuvant Chemotherapy (Alliance N0147)

无组织循环肿瘤DNA检测与基于FOLFOX的辅助化疗III期试验中的患者预后(Alliance N0147)

Sinicrope, Frank A; Segovia, Diana; Sharma, Nalin; Alberts, Steven R; Hardin, Aaron; Rich, Thereasa; Shi, Qian

Targeting the novel immune checkpoint KLRG1 is markedly therapeutic against cancer through multiple lymphocyte subsets.

靶向新型免疫检查点 KLRG1 可通过多种淋巴细胞亚群对癌症产生显著的治疗作用。

Jones Tyler Andrew, Shapiro Jason W, Sinicrope Stephen, Li Shuyin, Yasuda Kei, Iovino Matthew, Severe Nicolas, Pinkas Jan, Gajewski Thomas

Immune checkpoint blockade in locally advanced rectal cancer with deficient DNA mismatch repair: retrospective multicenter experience

免疫检查点阻断治疗DNA错配修复缺陷的局部晚期直肠癌:回顾性多中心经验

Emiloju, O E; Foster, N R; Shah, P; Opneja, A; Gupta, A; Singh, M; Bonneau, K; Steinert, K O; Saeed, A; Strickler, J H; Overman, M J; Sinicrope, F A

Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors

对于错配修复缺陷或微卫星不稳定性高、转移性结直肠癌且正在接受免疫检查点抑制剂治疗的患者,应尽早停止治疗。

Taieb, Julien; Ambrosini, Margherita; Alouani, Emily; Lonardi, Sara; Sinicrope, Frank A; Decraecker, Marie; Boileve, Alice; Hafliger, Emilie; Mazard, Thibault; Pernot, Simon; Parent, Pauline; Ros, Javier; Overman, Michael J; Jayachandran, Priya; Nasca, Vincenzo; Salvatore, Lisa; Guimbaud, Rosine; Cremolini, Chiara; Tougeron, David; Pietrantonio, Filippo

Efficacy of immunotherapy in gastrointestinal (GI) tumors with mismatch repair deficient (MMRd) unusual phenotype: an AGEO real-world study

免疫疗法治疗错配修复缺陷(MMRd)异常表型胃肠道肿瘤的疗效:一项AGEO真实世界研究

Alouani, Emily; Taieb, Julien; Tougeron, David; Roces, Guillaume; Hollebecque, Antoine; Parent, Pauline; Pernot, Simon; Sinicrope, Frank A; Hautefeuille, Vincent; Ben-Abdelghani, Meher; Dutherage, Marie; Cohen, Romain; Hafliger, Emilie; Sclafani, Francesco; Muller, Marie; Perkins, Géraldine; Masson, Thérèse; Aparicio, Thomas; Coutzac, Clélia; Mazard, Thibault; Decraecker, Marie; Jaffrelot, Marion; Guimbaud, Rosine; Selves, Janick

Identification of Candidate Alterations Mediating KRASG12C Inhibitor Resistance in Advanced Colorectal and Pancreatic Cancers

鉴定介导晚期结直肠癌和胰腺癌中KRASG12C抑制剂耐药性的候选改变

Jazieh, Khalid; Tsai, Jill; Solomon, Sheila; Zhu, Mojun; Sinicrope, Frank A; Pedersen, Katrina S; Fernandez-Zapico, Martin E; Xie, Hao

Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer.

空间分辨多区域蛋白质组学预测错配修复缺陷型转移性结直肠癌的免疫治疗结果

Saberzadeh-Ardestani Bahar, Liu Zhenglong, Stein Mariam I, Sherman Will A, Trussoni Christy E, Abbott Charles W, Yan Dongyao, Smith Skyler, Shanmugam Kandavel, Graham Rondell P, Diallo Alos, Levy Joshua J, Ordog Tamas, Sinicrope Frank A

Novel CDK2/CDK9 inhibitor fadraciclib targets cell survival and DNA damage pathways and synergizes with encorafenib in human colorectal cancer cells with BRAF(V600E).

新型 CDK2/CDK9 抑制剂 fadraciclib 靶向细胞存活和 DNA 损伤通路,并与 encorafenib 在具有 BRAF(V600E) 的人类结直肠癌细胞中产生协同作用

Mohiuddin Md, Póvoa Vanda, Fior Rita, Sinicrope Frank A

Intergroup randomized phase III study of adjuvant FOLFIRI, FOLFOX, or 5-FU/leucovorin for stage II/III rectal cancer: ECOG-ACRIN E3201

一项针对 II/III 期直肠癌的辅助治疗方案(FOLFIRI、FOLFOX 或 5-FU/亚叶酸钙)的多中心随机 III 期研究:ECOG-ACRIN E3201

Kam, Audrey E; Zhao, Fengmin; Meropol, Neal J; Giantonio, Bruce J; Diasio, Robert B; Flynn, Patrick J; Catalano, Paul; Hartner, Lee; Rowland, Kendrith M; Song, Wei; Mulcahy, Mary F; Sinicrope, Frank A; Whitehead, Robert P; Mayer, Robert J; Petrelli, Nicholas; O'Dwyer, Peter J; Hamilton, Stanley R; Cella, David; Benson, Al B