文献库，生知库 | 链接生命科学的每一步

日期影响因子

USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism

USP22 缺陷通过 PU.1 依赖性机制激活致癌 Kras，进而导致髓系白血病。

影响因子:23.1

doi:10.1182/blood-2017-10-811760

Melo-Cardenas, Johanna; Xu, Yuanming; Wei, Juncheng; Tan, Can; Kong, Sinyi; Gao, Beixue; Montauti, Elena; Kirsammer, Gina; Licht, Jonathan D; Yu, Jindan; Ji, Peng; Crispino, John D; Fang, Deyu

发表日期：2018

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Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas

内质网驻留的E3泛素连接酶Hrd1通过降解死亡受体CD95/Fas来调控B细胞免疫。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1606742113

Kong, Sinyi; Yang, Yi; Xu, Yuanming; Wang, Yajun; Zhang, Yusi; Melo-Cardenas, Johanna; Xu, Xiangping; Gao, Beixue; Thorp, Edward B; Zhang, Donna D; Zhang, Bin; Song, Jianxun; Zhang, Kezhong; Zhang, Jianning; Zhang, Jinping; Li, Huabin; Fang, Deyu

细胞生物学

免疫/内分泌

发表日期：2016

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Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1

泛素特异性蛋白酶22是CCNB1的去泛素化酶。

期刊:Cell Discovery

影响因子:12.5

doi:10.1038/celldisc.2015.28

Lin, Zhenghong; Tan, Can; Qiu, Quan; Kong, Sinyi; Yang, Heeyoung; Zhao, Fang; Liu, Zhaojian; Li, Jinping; Kong, Qingfei; Gao, Beixue; Barrett, Terry; Yang, Guang-Yu; Zhang, Jianing; Fang, Deyu

发表日期：2015

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Deleted in Breast Cancer 1 Suppresses B Cell Activation through RelB and Is Regulated by IKKα Phosphorylation

乳腺癌中缺失的 1 号基因通过 RelB 抑制 B 细胞活化并受 IKKα 磷酸化调控

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.1500713

Sinyi Kong, Hongxin Dong, Jianxun Song, Muthusamy Thiruppathi, Bellur S Prabhakar, Quan Qiu, Zhenghong Lin, Eduardo Chini, Bin Zhang, Deyu Fang

细胞生物学

发表日期：2015

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A Hrd way for MHC-II expression

MHC-II表达的Hrd途径

期刊:Oncotarget

doi:10.18632/oncotarget.4799

Melo-Cardenas, Johanna; Kong, Sinyi; Fang, Deyu

发表日期：2015

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Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation

炎症期间，Hrd1介导的BLIMP-1泛素化促进树突状细胞MHCII表达，从而启动CD4 T细胞。

期刊:Journal of Experimental Medicine

影响因子:10.6

doi:10.1084/jem.20140283

Yang, Heeyoung; Qiu, Quan; Gao, Beixue; Kong, Sinyi; Lin, Zhenghong; Fang, Deyu

树突状细胞

细胞生物学

树突状细胞

免疫/内分泌

发表日期：2014

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DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity

DBC1 通过负向调节替代 NF-κB 转录活性来抑制 B 细胞活化

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.1401798

Sinyi Kong, Muthusamy Thiruppathi, Quan Qiu, Zhenghong Lin, Hongxin Dong, Eduardo N Chini, Bellur S Prabhakar, Deyu Fang

发表日期：2014

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The class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis

III类组蛋白去乙酰化酶sirtuin 1在免疫抑制中的作用及其在类风湿性关节炎中的治疗潜力

期刊:Journal of Genetics and Genomics

影响因子:7.1

doi:10.1016/j.jgg.2013.04.001

Kong, Sinyi; Yeung, Pricilla; Fang, Deyu

免疫/内分泌

发表日期：2013

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USP10 antagonizes c-Myc transcriptional activation through SIRT6 stabilization to suppress tumor formation

USP10通过稳定SIRT6拮抗c-Myc转录激活，从而抑制肿瘤形成。

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2013.11.029

Lin, Zhenghong; Yang, Heeyoung; Tan, Can; Li, Jinping; Liu, Zhaojian; Quan, Qiu; Kong, Sinyi; Ye, Junsheng; Gao, Beixue; Fang, Deyu

发表日期：2013

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