Blocking of Transient Receptor Potential Vanilloid 1 (TRPV1) promotes terminal mitophagy in multiple myeloma, disturbing calcium homeostasis and targeting ubiquitin pathway and bortezomib-induced unfolded protein response
阻断瞬时受体电位香草酸受体1 (TRPV1) 可促进多发性骨髓瘤细胞的终末线粒体自噬，扰乱钙稳态，并靶向泛素通路和硼替佐米诱导的未折叠蛋白反应。
期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-020-00993-0
Beider, Katia; Rosenberg, Evgenia; Dimenshtein-Voevoda, Valeria; Sirovsky, Yaarit; Vladimirsky, Julia; Magen, Hila; Ostrovsky, Olga; Shimoni, Avichai; Bromberg, Zohar; Weiss, Lola; Peled, Amnon; Nagler, Arnon
多发性骨髓瘤
信号转导
线粒体
骨髓瘤
细胞生物学
自噬
TRPV1
