日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Functional correction and genome integrity with duplex base editing of β-thalassemic hematopoietic stem cells

利用β-地中海贫血造血干细胞的双链碱基编辑实现功能矫正和基因组完整性

期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-026-03974-7
Papaioannou, Nikoletta Y; Patsali, Petros; Klermund, Julia; Papasavva, Panayiota L; Andrieux, Geoffroy; Koniali, Lola; Naiisseh, Basma; Christou, Soteroula; Sitarou, Maria; Kleanthous, Marina; Cathomen, Toni; Lederer, Carsten W
发育与干细胞
碱基编辑
代谢
干细胞
细胞生物学
贫血
发表日期：2026
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Evaluation of Five Plasma miRNAs as Biomarkers for Minimally Invasive Staging of Liver Fibrosis in β-Thalassaemia Patients

评估五种血浆 miRNA 作为 β-地中海贫血患者肝纤维化微创分期生物标志物的价值

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26199543
Özkaramehmet, Sevgi; Andreou, Savanna; Yiangou, Kristia; Christou, Soteroula; Hadjigavriel, Michalis; Sitarou, Maria; Pyrovolaki, Katerina; Papanicolaou, Eleni; Flourou, Christina; Savvidou, Irene; Boutsikos, Panagiotis; Mendoni, Alexandra; Kleanthous, Marina; Phylactides, Marios; Lederer, Carsten W
miRNA
贫血
代谢
发表日期：2025
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Context base editing for splice correction of IVSI-110 β-thalassemia

用于 IVSI-110 β-地中海贫血剪接校正的上下文库编辑

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.5
doi:10.1016/j.omtn.2024.102183
Basma Naiisseh, Panayiota L Papasavva, Nikoletta Y Papaioannou, Marios Tomazou, Lola Koniali, Xenia Felekis, Constantina G Constantinou, Maria Sitarou, Soteroula Christou, Marina Kleanthous, Carsten W Lederer, Petros Patsali
代谢
贫血
发表日期：2024
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Evaluation of Mono- and Bi-Functional GLOBE-Based Vectors for Therapy of β-Thalassemia by HBBAS3 Gene Addition and Mutation-Specific RNA Interference

通过 HBBAS3 基因添加和突变特异性 RNA 干扰对 β-地中海贫血进行治疗的单体和双功能 GLOBE 载体的评估

期刊:Cells
影响因子:5.1
doi:10.3390/cells12242848
Lola Koniali, Christina Flouri, Markela I Kostopoulou, Nikoletta Y Papaioannou, Panayiota L Papasavva, Basma Naiisseh, Coralea Stephanou, Anthi Demetriadou, Maria Sitarou, Soteroula Christou, Michael N Antoniou, Marina Kleanthous, Petros Patsali, Carsten W Lederer
心血管
贫血
发表日期：2023
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High-efficiency editing in hematopoietic stem cells and the HUDEP-2 cell line based on in vitro mRNA synthesis

基于体外 mRNA 合成的造血干细胞和 HUDEP-2 细胞系高效编辑

期刊:Frontiers in Genome Editing
影响因子:4.9
doi:10.3389/fgeed.2023.1141618
Nikoletta Y Papaioannou, Petros Patsali, Basma Naiisseh, Panayiota L Papasavva, Lola Koniali, Ryo Kurita, Yukio Nakamura, Soteroula Christou, Maria Sitarou, Claudio Mussolino, Toni Cathomen, Marina Kleanthous, Carsten W Lederer
发育与干细胞
干细胞
发表日期：2023
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Effect of HBB genotype on survival in a cohort of transfusion-dependent thalassemia patients in Cyprus

HBB基因型对塞浦路斯一组输血依赖型地中海贫血患者生存率的影响

期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2020.260224
Kountouris, Petros; Michailidou, Kyriaki; Christou, Soteroula; Hadjigavriel, Michael; Sitarou, Maria; Kolnagou, Anita; Kleanthous, Marina; Telfer, Paul
贫血
代谢
发表日期：2021
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Sex-specific transcriptional profiles identified in β-thalassemia patients

在β-地中海贫血患者中发现了性别特异性转录谱

期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2020.248013
Nanou, Aikaterini; Toumpeki, Chrisavgi; Fanis, Pavlos; Bianchi, Nicoletta; Cosenza, Lucia Carmela; Zuccato, Cristina; Sentis, George; Giagkas, Giorgos; Stephanou, Coralea; Phylactides, Marios; Christou, Soteroula; Hadjigavriel, Michalis; Sitarou, Maria; Lederer, Carsten W; Gambari, Roberto; Kleanthous, Marina; Katsantoni, Eleni
贫血
代谢
发表日期：2021
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Distinct miRNA Signatures and Networks Discern Fetal from Adult Erythroid Differentiation and Primary from Immortalized Erythroid Cells

独特的 miRNA 特征和网络可辨别胎儿红细胞与成人红细胞的分化以及原代红细胞与永生化红细胞

期刊:International Journal of Molecular Sciences
影响因子:0.7
doi:10.3390/ijms22073626
Panayiota L Papasavva, Nikoletta Y Papaioannou, Petros Patsali, Ryo Kurita, Yukio Nakamura, Maria Sitarou, Soteroulla Christou, Marina Kleanthous, Carsten W Lederer
免疫
细胞生物学
红细胞
发表日期：2021
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Relative and Absolute Quantification of Aberrant and Normal Splice Variants in HBBIVSI-110 (G > A) β-Thalassemia

HBBIVSI-110 (G > A) β-地中海贫血中异常和正常剪接变体的相对和绝对定量

期刊:International Journal of Molecular Sciences
影响因子:0.7
doi:10.3390/ijms21186671
Petros Patsali, Panayiota Papasavva, Soteroulla Christou, Maria Sitarou, Michael N Antoniou, Carsten W Lederer, Marina Kleanthous
心血管
贫血
发表日期：2020
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Correction of IVS I-110(G>A) β-thalassemia by CRISPR/Cas-and TALEN-mediated disruption of aberrant regulatory elements in human hematopoietic stem and progenitor cells

利用 CRISPR/Cas 和 TALEN 介导的人类造血干细胞和祖细胞中异常调控元件的破坏来纠正 IVS I-110(G>A) β-地中海贫血

期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2018.215178
Patsali, Petros; Turchiano, Giandomenico; Papasavva, Panayiota; Romito, Marianna; Loucari, Constantinos C; Stephanou, Coralea; Christou, Soteroulla; Sitarou, Maria; Mussolino, Claudio; Cornu, Tatjana I; Antoniou, Michael N; Lederer, Carsten W; Cathomen, Toni; Kleanthous, Marina
发育与干细胞
信号转导
代谢
干细胞
细胞生物学
贫血
发表日期：2019
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