日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Recombinant-Chemosynthetic Biosensors for Probing Cell Surface Signaling of Red Blood Cells and Other Cells

用于探测红细胞和其他细胞表面信号传导的重组化学合成生物传感器

Ubeysinghe, Sithurandi; Sebilleau, Chloe O; Thotamune, Waruna; Rajarathna, Chathuri; Azibere, Samuel; Tennakoon, Mithila; Payton, John L; Sprague, Randy S; Martin, R Scott; Sucheck, Steven J; Karunarathne, Ajith

AGS3-based optogenetic GDI induces GPCR-independent Gβγ signalling and macrophage migration

基于AGS3的光遗传学GDI诱导GPCR非依赖性Gβγ信号传导和巨噬细胞迁移

Thotamune, Waruna; Ubeysinghe, Sithurandi; Rajarathna, Chathuri; Kankanamge, Dinesh; Olupothage, Koshala; Chandu, Aditya; Copits, Bryan A; Karunarathne, Ajith

Optical control of cell-surface and endomembrane-exclusive β-adrenergic receptor signaling

细胞表面和内膜专属β-肾上腺素受体信号的光学控制

Waruna Thotamune, Sithurandi Ubeysinghe, Kendra K Shrestha, Mahmoud Elhusseiny Mostafa, Michael C Young, Ajith Karunarathne

Spatiotemporal Optical Control of Gαq-PLCβ Interactions.

Gαq-PLCβ相互作用的时空光学控制

Ubeysinghe Sithurandi, Kankanamge Dinesh, Thotamune Waruna, Wijayaratna Dhanushan, Mohan Thomas M 3rd, Karunarathne Ajith

AGS3-based optogenetic GDI induces GPCR-independent Gβγ signaling and macrophage migration

基于 AGS3 的光遗传学 GDI 诱导 GPCR 独立的 Gβγ 信号传导和巨噬细胞迁移

Waruna Thotamune, Sithurandi Ubeysinghe, Chathuri Rajarathna, Dinesh Kankanamge, Koshala Olupothage, Aditya Chandu, Bryan A Copits, Ajith Karunarathne

Optical Control of Cell-Surface and Endomembrane-Exclusive β-Adrenergic Receptor Signaling

细胞表面和内膜特异性β-肾上腺素能受体信号的光学控制

Thotamune, Waruna; Ubeysinghe, Sithurandi; Shrestha, Kendra K; Mostafa, Mahmoud Elhusseiny; Young, Michael C; Karunarathne, Ajith

The spatial distribution of GPCR and Gβγ activity across a cell dictates PIP3 dynamics

细胞内 GPCR 和 Gβγ 活性的空间分布决定了 PIP3 的动态

Dhanushan Wijayaratna, Kasun Ratnayake, Sithurandi Ubeysinghe, Dinesh Kankanamge, Mithila Tennakoon, Ajith Karunarathne

Molecular regulation of PLCβ signaling

PLCβ信号传导的分子调控

Ubeysinghe, Sithurandi; Wijayaratna, Dhanushan; Kankanamge, Dinesh; Karunarathne, Ajith

Dissociation of the G protein βγ from the Gq-PLCβ complex partially attenuates PIP2 hydrolysis

G蛋白βγ从Gq-PLCβ复合物中解离可部分减弱PIP2水解

Kankanamge, Dinesh; Ubeysinghe, Sithurandi; Tennakoon, Mithila; Pantula, Priyanka Devi; Mitra, Kishalay; Giri, Lopamudra; Karunarathne, Ajith

Subtype-dependent regulation of Gβγ signalling

Gβγ信号传导的亚型依赖性调控

Tennakoon, Mithila; Senarath, Kanishka; Kankanamge, Dinesh; Ratnayake, Kasun; Wijayaratna, Dhanushan; Olupothage, Koshala; Ubeysinghe, Sithurandi; Martins-Cannavino, Kimberly; Hébert, Terence E; Karunarathne, Ajith