日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Multiplex gene-editing strategy to engineer allogeneic EGFR-targeting CAR T-cells with improved efficacy against solid tumors

利用多重基因编辑策略改造同种异体EGFR靶向CAR T细胞，以提高其对实体瘤的疗效

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66737-1
Murray, Ryan; Chowdhury, Md Raihan; Botticello-Romero, Nuria Roxana; Desai, Kashvi; Chilakapati, Shanmuga Reddy; Chong, Brian; Xia, Yixue; Messana, Angelica; Sobon, Hanna; Rocha, Joe; Musenge, Faith; Camblin, Adam; Ciaramella, Giuseppe; Sitkovsky, Michail V; Maldini, Colby R; Hatfield, Stephen M
T细胞
EGF
EGFR
T细胞
细胞生物学
免疫/内分泌
发表日期：2025
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Oxygen-carrying nanoemulsions and respiratory hyperoxia eliminate tumor hypoxia-induced immunosuppression.

载氧纳米乳剂和呼吸高氧可消除肿瘤缺氧引起的免疫抑制

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.174675
Halpin-Veszeleiova Katarina, Mallouh Michael P, Williamson Lucy M, Apro Ashley C, Botticello-Romero Nuria R, Bahr Camille, Shin Maureen, Ward Kelly M, Rosenberg Laura, Ritov Vladimir B, Sitkovsky Michail V, Jackson Edwin K, Spiess Bruce D, Hatfield Stephen M
肿瘤
肿瘤免疫
发表日期：2025
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Oxygen-Generating Cryogels Restore T Cell Mediated Cytotoxicity in Hypoxic Tumors.

产氧冷冻凝胶可恢复缺氧肿瘤中T细胞介导的细胞毒性

期刊:Advanced Functional Materials
影响因子:19
doi:10.1002/adfm.202102234
Colombani Thibault, Eggermont Loek J, Hatfield Stephen M, Rogers Zachary J, Rezaeeyazdi Mahboobeh, Memic Adnan, Sitkovsky Michail V, Bencherif Sidi A
细胞生物学
肿瘤
T细胞
发表日期：2021
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Immunological mechanisms of the antitumor effects of supplemental oxygenation

补充氧疗抗肿瘤作用的免疫机制

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aaa1260
Hatfield, Stephen M; Kjaergaard, Jorgen; Lukashev, Dmitriy; Schreiber, Taylor H; Belikoff, Bryan; Abbott, Robert; Sethumadhavan, Shalini; Philbrook, Phaethon; Ko, Kami; Cannici, Ryan; Thayer, Molly; Rodig, Scott; Kutok, Jeffrey L; Jackson, Edwin K; Karger, Barry; Podack, Eckhard R; Ohta, Akio; Sitkovsky, Michail V
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2015
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Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists

肿瘤免疫学家面临的下一个挑战是：具有敌对性、缺氧-A2-腺苷能肿瘤生物学特性的肿瘤免疫学家。

期刊:Cancer Immunology Research
影响因子:8.2
doi:10.1158/2326-6066.CIR-14-0075
Sitkovsky, Michail V; Hatfield, Stephen; Abbott, Robert; Belikoff, Bryan; Lukashev, Dmitriy; Ohta, Akio
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2014
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In vivo hypoxic preconditioning protects from warm liver ischemia-reperfusion injury through the adenosine A2B receptor.

体内缺氧预处理通过腺苷 A2B 受体保护肝脏免受温缺血再灌注损伤

期刊:Transplantation
影响因子:5
doi:10.1097/TP.0b013e31826a9a46
Choukèr Alexander, Ohta Akio, Martignoni André, Lukashev Dmitriy, Zacharia Lefteris C, Jackson Edwin K, Schnermann Jürgen, Ward Jerrold M, Kaufmann Ines, Klaunberg Brenda, Sitkovsky Michail V, Thiel Manfred
毒理研究
肝损伤
低氧缺氧
发表日期：2012
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Differential regulation of HIF-1alpha isoforms in murine macrophages by TLR4 and adenosine A(2A) receptor agonists.

TLR4 和腺苷 A(2A) 受体激动剂对小鼠巨噬细胞中 HIF-1α 亚型的差异性调节

期刊:Journal of Leukocyte Biology
影响因子:3.1
doi:10.1189/jlb.0109021
Ramanathan Madhuri, Luo Wenting, Csóka Balázs, Haskó György, Lukashev Dmitry, Sitkovsky Michail V, Leibovich Samuel Joseph
细胞生物学
巨噬细胞
发表日期：2009
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Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway

缺氧和A2A腺苷受体在肝组织保护性生理抗炎通路中的关键作用

期刊:Molecular Medicine
影响因子:6.4
doi:10.2119/2007-00075.Chouker
Choukèr, Alexander; Thiel, Manfred; Lukashev, Dmitriy; Ward, Jerrold M; Kaufmann, Ines; Apasov, Sergey; Sitkovsky, Michail V; Ohta, Akio
信号转导
发表日期：2008
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Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha -deficient chimeric mice

缺氧诱导因子1α缺陷嵌合小鼠的B淋巴细胞发育异常和自身免疫

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.052706699
Kojima, Hidefumi; Gu, Hua; Nomura, Saeko; Caldwell, Charles C; Kobata, Tetsuji; Carmeliet, Peter; Semenza, Gregg L; Sitkovsky, Michail V
细胞生物学
发育与干细胞
免疫/内分泌
发表日期：2002
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Purification and Recognition of Recombinant Mouse P2X(1) Receptors Expressed in a Baculovirus System

杆状病毒系统中表达的重组小鼠P2X(1)受体的纯化和鉴定

期刊:Drug Development Research
影响因子:4.2
doi:10.1002/1098-2299(20000901)51:1<7::AID-DDR2>3.0.CO;2-W
Chen, Liping; Hardwick, James P; McPhie, Peter; Sitkovsky, Michail V; Jacobson, Kenneth A
微生物学
信号转导
Mouse
发表日期：2000
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