His224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7
His224 会改变 R2 药物结合位点，而 Phe218 会影响金属β-内酰胺酶 VIM-7 的催化效率。
期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.02735-13
Leiros, Hanna-Kirsti S; Skagseth, Susann; Edvardsen, Kine Susann Waade; Lorentzen, Marit Sjo; Bjerga, Gro Elin Kjæreng; Leiros, Ingar; Samuelsen, Ørjan
