日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hyaluronan-Based Glioblastoma Tumor Constructs Maintain Patient Tumor Drug Responses and Genomic Parity.

基于透明质酸的胶质母细胞瘤肿瘤构建体可维持患者肿瘤药物反应和基因组平衡。

Sivakumar Hemamylammal, Forsythe Steven D, Laxton Adrian W, Tatter Stephen B, Miller Lance D, Strowd Roy E, Skardal Aleksander

Establishment of a patient-derived adrenocortical carcinoma 3D tumor construct platform for evaluation of therapeutic strategies

建立患者来源的肾上腺皮质癌三维肿瘤构建平台,用于评估治疗策略

Rodriguez, Marco A; Sivakumar, Hemamylammal; Popova, Liudmila; Derakhshesh, Saeed; Chopyk, Daniel; Miles, Wayne O; Dedhia, Priya H; Skardal, Aleksander

A Microfluidic Blood Brain Barrier Model to Study the Influence of Glioblastoma Tumor Cells on BBB Function

利用微流控血脑屏障模型研究胶质母细胞瘤细胞对血脑屏障功能的影响

DePalma, Thomas; Rodriguez, Marco; Kollin, Luke; Hughes, Kennedy; Jones, Katie; Stagner, Emerie; Venere, Monica; Skardal, Aleksander

Evaluation of natural killer cell tumor homing and effector function in response to CDK4/6 and AURKA inhibition in a melanoma tumor-on-a-chip platform

在黑色素瘤芯片肿瘤模型中评估 CDK4/6 和 AURKA 抑制对自然杀伤细胞肿瘤归巢和效应功能的影响

Chakraborty, Srija; Durham, Connor; Bharti, Vijaya; Capece, Marina; Davies, Alexander E; Vilgelm, Anna; Skardal, Aleksander

Fibroblasts drive differential response in immunotherapy via IL-6 in bioengineered 3D cancer constructs

成纤维细胞通过IL-6在生物工程3D癌症构建体中驱动免疫疗法的差异性反应

Chakraborty, Srija; Rodriguez, Marco; Skardal, Aleksander

An osteosarcoma-on-a-chip model for studying osteosarcoma matrix-cell interactions and drug responses

用于研究骨肉瘤基质-细胞相互作用和药物反应的芯片骨肉瘤模型

Lu, Zuyan; Miao, XiangWan; Zhang, Chenyu; Sun, Binbin; Skardal, Aleksander; Atala, Anthony; Ai, Songtao; Gong, JiaNing; Hao, Yongqiang; Zhao, Jie; Dai, Kerong

Tuning a bioengineered hydrogel for studying astrocyte reactivity in glioblastoma.

调整生物工程水凝胶以研究胶质母细胞瘤中星形胶质细胞的反应性

DePalma Thomas J, Hisey Colin L, Hughes Kennedy, Fraas David, Tawfik Marie, Scharenberg Jason, Wiggins Sydney, Nguyen Kim Truc, Hansford Derek J, Reátegui Eduardo, Skardal Aleksander

RCAN1.4 regulates tumor cell engraftment and invasion in a thyroid cancer to lung metastasis-on-a-chip microphysiological system

RCAN1.4 在甲状腺癌肺转移芯片微生理系统中调控肿瘤细胞的植入和侵袭。

Nairon, Kylie G; Nigam, Akanksha; Khanal, Tilak; Rodriguez, Marco A; Rajan, Neel; Anderson, Sydney R; Ringel, Matthew D; Skardal, Aleksander

A Multicellular Mechanochemical Model to Investigate Tumor Microenvironment Remodeling and Pre-Metastatic Niche Formation

利用多细胞力学化学模型研究肿瘤微环境重塑和转移前微环境形成

Hirway, Shreyas U; Nairon, Kylie G; Skardal, Aleksander; Weinberg, Seth H

Grand challenges in organoid and organ-on-a-chip technologies

类器官和芯片器官技术面临的重大挑战

Skardal, Aleksander