日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Adenine base editor for knockout of proteins: A practical guide from design to analysis with updated MultiEditRbatch

用于蛋白质敲除的腺嘌呤碱基编辑器：从设计到分析的实用指南（含更新版 MultiEditRbatch）

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2026.102908
Eaton, Ella J; Wick, Bryce J; Chacón, Jeremy S; Wang, Amy J; Kluesner, Mitchell; Barnes, Jackson T; Kar, Bibekananda; Wang, Minjing; Johnson, Matthew J; Skeate, Joseph G; Webber, Beau R; Moriarity, Branden S
碱基编辑
发表日期：2026
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Non-viral TcBuster transposon engineering of CD70-CAR natural killer cells for the treatment of osteosarcoma.

利用非病毒 TcBuster 转座子工程改造 CD70-CAR 自然杀伤细胞，用于治疗骨肉瘤。

期刊:Molecular Therapy Oncology
影响因子:5.3
doi:10.1016/j.omton.2025.201119
Robbins Gabrielle M, Chang Jae-Woong, Krueger Joshua B, Vue Young Y, Gilkey Alexandria K, Folsom Timothy D, Jubenville Tyler, Skeate Joseph G, Langworthy Benjamin W, Fitzgerald Katelyn M, Peterson Joseph J, Stelljes Erin M, Largaespada David A, Rahrmann Eric P, Webber Beau R, Moriarity Branden S
骨肉瘤
细胞生物学
自然杀伤细胞
CD7
CD70
发表日期：2026
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Functional genomics for improving adoptive T-cell transfer therapies

利用功能基因组学改进过继性T细胞转移疗法

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2025-013286
Skeate, Joseph G; Lee, Chang-Jung; Stewart, Carli; Fischbach, Mathew J; Kar, Bibekananda; Tsai, Alexander K; Kenderian, Saad S; Stromnes, Ingunn M; Largaespada, David A; Moriarity, Branden S; Rogers, Laura M
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2025
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Precision enhancement of CAR-NK cells through non-viral engineering and highly multiplexed base editing.

通过非病毒工程和高通量碱基编辑实现CAR-NK细胞的精确增强

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-009560
Wang Minjing, Krueger Joshua B, Gilkey Alexandria K, Stelljes Erin M, Kluesner Mitchell G, Pomeroy Emily J, Skeate Joseph G, Slipek Nicholas J, Lahr Walker S, Claudio Vázquez Patricia N, Zhao Yueting, Bell Jason B, Clement Kendell, Eaton Ella J, Laoharawee Kanut, Chang Jae-Woong, Webber Beau R, Moriarity Branden S
细胞生物学
Viral
发表日期：2025
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Installation of dominant-negative mutations in FAS and TGFβR2 via base editing in primary T cells

通过碱基编辑在原代T细胞中引入FAS和TGFβR2的显性负突变

期刊:Molecular Therapy Oncology
影响因子:4.5
doi:10.1016/j.omton.2025.201063
Bryce J Wick ，Mitchell G Kluesner ，Nicholas J Slipek ，Joseph G Skeate ，Ethan M Niemeyer ，Beau R Webber ，Branden S Moriarity
FAS
T细胞
发表日期：2025
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Best practices for supporting researchers' mental health in emotionally demanding research across academic and non-academic contexts

在学术和非学术环境中，如何为从事高压力研究的研究人员提供心理健康支持方面的最佳实践

期刊:International Journal of Qualitative Studies on Health and Well-Being
影响因子:2.3
doi:10.1080/17482631.2025.2464380
Quinton, Mary L; Shepherd, Karen L; Cumming, Jennifer; Tidmarsh, Grace; Dauvermann, Maria R; Griffiths, Sian L; Reynard, Sally; Skeate, Amanda; Fernandes, Anita; Choucair, Tasneem; Downs, James; Harrison Dening, Karen; McDonough, Meghan H; Mitchell, Lizzie; Rhind, Daniel J A; Tresadern, Charlie
发表日期：2025
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Installation of Dominant-Negative Mutations in FAS and TGFβR2 via Base Editing in Primary T Cells.

通过碱基编辑在原代 T 细胞中引入 FAS 和 TGFβR2 的显性负突变。

期刊:
影响因子:
doi:10.1101/2025.09.11.675648
Wick Bryce J, Kluesner Mitchell G, Slipek Nicholas J, Skeate Joseph G, Niemeyer Ethan M, Webber Beau R, Moriarity Branden S
T细胞
碱基编辑
细胞生物学
TGFβ
FAS
发表日期：2025
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A Singular Base Editing Platform for Polyfunctional Multiplex Engineering of Immune Cells.

用于免疫细胞多功能多重工程的单一碱基编辑平台

期刊:
影响因子:
doi:10.1101/2025.07.11.664404
Skeate Joseph G, Slipek Nicholas J, Lahr Walker S, Roy Shambojit, Wick Bryce J, Stelljes Erin M, Gilkey Alexandria K, Thenge Prateek P, Diers Miechaleen D, Kar Bibekananda, Krueger Joshua B, Niemeyer Ethan M, Lonetree Cara-Lin, Kluesner Mitchell G, Bell Jason B, Clement Kendell, Provenzano Paolo, Moriarity Branden S, Webber Beau R
细胞生物学
发表日期：2025
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Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair

Cas9 通过同源介导的末端连接 DNA 修复诱导人类原代 T 细胞中大型 DNA 有效载荷的靶向整合

期刊:Nature Biomedical Engineering
影响因子:26.8
doi:10.1038/s41551-023-01157-4
Beau R Webber #, Matthew J Johnson #, Joseph G Skeate, Nicholas J Slipek, Walker S Lahr, Anthony P DeFeo, Lauren J Mills, Xiaohong Qiu, Blaine Rathmann, Miechaleen D Diers, Bryce Wick, Tom Henley, Modassir Choudhry, Timothy K Starr, R Scott McIvor, Branden S Moriarity2
免疫
细胞生物学
T细胞
AROS
发表日期：2024
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Evolution of the clinical-stage hyperactive TcBuster transposase as a platform for robust non-viral production of adoptive cellular therapies.

临床阶段高活性 TcBuster 转座酶的演变，使其成为强大的非病毒过继细胞疗法生产的平台

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2024.04.024
Skeate Joseph G, Pomeroy Emily J, Slipek Nicholas J, Jones Bryan J, Wick Bryce J, Chang Jae-Woong, Lahr Walker S, Stelljes Erin M, Patrinostro Xiaobai, Barnes Blake, Zarecki Trevor, Krueger Joshua B, Bridge Jacob E, Robbins Gabrielle M, McCormick Madeline D, Leerar John R, Wenzel Kari T, Hornberger Kathlyn M, Walker Kirsti, Smedley Dalton, Largaespada David A, Otto Neil, Webber Beau R, Moriarity Branden S
细胞生物学
Viral
发表日期：2024
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