日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synaptic Vesicle Glycoprotein 2A Is Affected in the Central Nervous System of Mice with Huntington Disease and in the Brain of a Human with Huntington Disease Postmortem

突触囊泡糖蛋白 2A 在亨廷顿病小鼠的中枢神经系统和亨廷顿病患者死后的大脑中受到影响

Daniele Bertoglio, Jeroen Verhaeghe, Leonie Wyffels, Alan Miranda, Sigrid Stroobants, Ladislav Mrzljak, Celia Dominguez, Mette Skinbjerg, Jonathan Bard, Longbin Liu, Ignacio Munoz-Sanjuan, Steven Staelens

Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington's disease

对新型放射性配体[11C]CHDI-626进行纵向临床前评估,用于亨廷顿病中突变亨廷顿蛋白聚集体的PET成像

Bertoglio, Daniele; Verhaeghe, Jeroen; Miranda, Alan; Wyffels, Leonie; Stroobants, Sigrid; Mrzljak, Ladislav; Khetarpal, Vinod; Skinbjerg, Mette; Liu, Longbin; Dominguez, Celia; Munoz-Sanjuan, Ignacio; Bard, Jonathan; Staelens, Steven

Kinetic Modelling and Test-Retest Reproducibility for the Dopamine D(1)R Radioligand [(11)C]SCH23390 in Healthy and Diseased Mice

健康和患病小鼠中多巴胺D(1)R放射性配体[(11)C]SCH23390的动力学模型和重测信度

Bertoglio, Daniele; Verhaeghe, Jeroen; Miranda, Alan; Wyffels, Leonie; Stroobants, Sigrid; Dominguez, Celia; Munoz-Sanjuan, Ignacio; Skinbjerg, Mette; Liu, Longbin; Staelens, Steven

Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington's Disease: a Longitudinal PET Study

亨廷顿氏病小鼠模型中 1 型代谢型谷氨酸受体可用性升高:一项纵向 PET 研究

Daniele Bertoglio, Jeroen Verhaeghe, Špela Korat, Alan Miranda, Klaudia Cybulska, Leonie Wyffels, Sigrid Stroobants, Ladislav Mrzljak, Celia Dominguez, Mette Skinbjerg, Longbin Liu, Ignacio Munoz-Sanjuan, Steven Staelens

In vitro and In vivo Assessment of Suitable Reference Region and Kinetic Modelling for the mGluR1 Radioligand [(11)C]ITDM in Mice

体外和体内评估小鼠中mGluR1放射性配体[(11)C]ITDM的合适参考区域和动力学模型

Bertoglio, Daniele; Verhaeghe, Jeroen; Korat, Špela; Miranda, Alan; Wyffels, Leonie; Stroobants, Sigrid; Mrzljak, Ladislav; Dominguez, Celia; Liu, Longbin; Skinbjerg, Mette; Munoz-Sanjuan, Ignacio; Staelens, Steven

Presynaptic dopamine in schizophrenia

精神分裂症中的突触前多巴胺

Miyake, Nobumi; Thompson, Judy; Skinbjerg, Mette; Abi-Dargham, Anissa

D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model

D2多巴胺受体内化延长了苯丙胺给药后放射性配体结合的下降:一项在受体内化缺陷小鼠模型中进行的PET研究

Skinbjerg, Mette; Liow, Jeih-San; Seneca, Nicholas; Hong, Jinsoo; Lu, Shuiyu; Thorsell, Annika; Heilig, Markus; Pike, Victor W; Halldin, Christer; Sibley, David R; Innis, Robert B

Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors

2-甲氧基-N-丙基去甲阿扑吗啡与D2和D3多巴胺受体相互作用的药理学特征

Skinbjerg, Mette; Namkung, Yoon; Halldin, Christer; Innis, Robert B; Sibley, David R

Arrestin3 mediates D(2) dopamine receptor internalization

Arrestin3介导D(2)多巴胺受体内化

Skinbjerg, Mette; Ariano, Marjorie A; Thorsell, Annika; Heilig, Markus; Halldin, Christer; Innis, Robert B; Sibley, David R

Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA: a dopamine agonist radioligand

[11C]MNPA(一种多巴胺激动剂放射性配体)在猴子体内的动力学脑分析和全身成像

Seneca, Nicholas; Skinbjerg, Mette; Zoghbi, Sami S; Liow, Jeih-San; Gladding, Robert L; Hong, Jinsoo; Kannan, Pavitra; Tuan, Edward; Sibley, David R; Halldin, Christer; Pike, Victor W; Innis, Robert B