日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

热点自身免疫T细胞受体结合是病原体和胰岛素肽交叉反应的基础

Cole, David K; Bulek, Anna M; Dolton, Garry; Schauenberg, Andrea J; Szomolay, Barbara; Rittase, William; Trimby, Andrew; Jothikumar, Prithiviraj; Fuller, Anna; Skowera, Ania; Rossjohn, Jamie; Zhu, Cheng; Miles, John J; Peakman, Mark; Wooldridge, Linda; Rizkallah, Pierre J; Sewell, Andrew K

β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure

1 型糖尿病中 β 细胞特异性 CD8 T 细胞表型反映了慢性自身抗原暴露

Skowera, Ania; Ladell, Kristin; McLaren, James E; Dolton, Garry; Matthews, Katherine K; Gostick, Emma; Kronenberg-Versteeg, Deborah; Eichmann, Martin; Knight, Robin R; Heck, Susanne; Powrie, Jake; Bingley, Polly J; Dayan, Colin M; Miles, John J; Sewell, Andrew K; Price, David A; Peakman, Mark

Peptide length determines the outcome of TCR/peptide-MHCI engagement.

肽链长度决定了TCR/肽-MHCI结合的结果

Ekeruche-Makinde Julia, Miles John J, van den Berg Hugo A, Skowera Ania, Cole David K, Dolton Garry, Schauenburg Andrea J A, Tan Mai Ping, Pentier Johanne M, Llewellyn-Lacey Sian, Miles Kim M, Bulek Anna M, Clement Mathew, Williams Tamsin, Trimby Andrew, Bailey Mick, Rizkallah Pierre, Rossjohn Jamie, Peakman Mark, Price David A, Burrows Scott R, Sewell Andrew K, Wooldridge Linda

Circulating preproinsulin signal peptide-specific CD8 T cells restricted by the susceptibility molecule HLA-A24 are expanded at onset of type 1 diabetes and kill β-cells

循环中受易感分子HLA-A24限制的胰岛素原信号肽特异性CD8 T细胞在1型糖尿病发病时扩增,并杀死β细胞。

Kronenberg, Deborah; Knight, Robin R; Estorninho, Megan; Ellis, Richard J; Kester, Michel G; de Ru, Arnoud; Eichmann, Martin; Huang, Guo C; Powrie, Jake; Dayan, Colin M; Skowera, Ania; van Veelen, Peter A; Peakman, Mark

Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers

蛋白激酶抑制剂可显著提高肽-MHC四聚体对T细胞的物理检测能力。

Lissina, Anna; Ladell, Kristin; Skowera, Ania; Clement, Matthew; Edwards, Emily; Seggewiss, Ruth; van den Berg, Hugo A; Gostick, Emma; Gallagher, Kathleen; Jones, Emma; Melenhorst, J Joseph; Godkin, Andrew J; Peakman, Mark; Price, David A; Sewell, Andrew K; Wooldridge, Linda

Immunological dysfunction, vaccination and Gulf War illness

免疫功能障碍、疫苗接种和海湾战争综合症

Peakman, Mark; Skowera, Ania; Hotopf, Matthew

Identification of a naturally processed cytotoxic CD8 T-cell epitope of coxsackievirus B4, presented by HLA-A2.1 and located in the PEVKEK region of the P2C nonstructural protein.

鉴定出柯萨奇病毒 B4 的天然加工细胞毒性 CD8 T 细胞表位,该表位由 HLA-A2.1 呈递,位于 P2C 非结构蛋白的 PEVKEK 区域

Varela-Calvino Ruben, Skowera Ania, Arif Sefina, Peakman Mark