日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rb substantially compensates for the double loss of p130 and p107 in adult but not embryonic neural stem cell lineages.

Rb 可以显著补偿成年神经干细胞谱系中 p130 和 p107 的双重缺失,但不能补偿胚胎神经干细胞谱系中的缺失

Swaidan Reem, Daher Ahmad, Bejjani Anthony T, El Atie Yara E, Chehab Yasmina, Bou Hamdan Razan, Vandenbosch Renaud, Slack Ruth S, Omais Saad, Ghanem Noël

Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration

神经退行性疾病动物模型中tRNA衍生的小非编码RNA的独特指纹图谱

Baindoor, Sharada; Gibriel, Hesham A Y; Venø, Morten T; Su, Junyi; Morrissey, Elena Perez; Jirström, Elisabeth; Woods, Ina; Kenny, Aidan; Alves, Mariana; Halang, Luise; Fabbrizio, Paola; Bilen, Maria; Engel, Tobias; Hogg, Marion C; Bendotti, Caterina; Nardo, Giovanni; Slack, Ruth S; Kjems, Jørgen; Prehn, Jochen H M

DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress

DJ-1通过上调内质网应激后的ATF4来调节未折叠蛋白反应和细胞死亡。

Yang, Jungwoo; Kim, Kwang Soo; Iyirhiaro, Grace O; Marcogliese, Paul C; Callaghan, Steve M; Qu, Dianbo; Kim, Woo Jae; Slack, Ruth S; Park, David S

Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson's disease

LRRK2通过WAVE2复合物稳定作用调节髓系细胞吞噬作用在帕金森病中发生改变。

Kim, Kwang Soo; Marcogliese, Paul C; Yang, Jungwoo; Callaghan, Steve M; Resende, Virginia; Abdel-Messih, Elizabeth; Marras, Connie; Visanji, Naomi P; Huang, Jana; Schlossmacher, Michael G; Trinkle-Mulcahy, Laura; Slack, Ruth S; Lang, Anthony E; Park, David S

Comparative analysis of Parkinson's disease-associated genes in mice reveals altered survival and bioenergetics of Parkin-deficient dopamine neurons

对小鼠帕金森病相关基因的比较分析揭示了帕金蛋白缺陷型多巴胺神经元的存活率和生物能量学改变

Giguère, Nicolas; Pacelli, Consiglia; Saumure, Caroline; Bourque, Marie-Josée; Matheoud, Diana; Levesque, Daniel; Slack, Ruth S; Park, David S; Trudeau, Louis-Éric

LRRK2(I2020T) functional genetic interactors that modify eye degeneration and dopaminergic cell loss in Drosophila

LRRK2(I2020T)功能性遗传互作因子可改变果蝇的眼睛退化和多巴胺能细胞丢失

Marcogliese, Paul C; Abuaish, Sameera; Kabbach, Ghassan; Abdel-Messih, Elizabeth; Seang, Sarah; Li, Gang; Slack, Ruth S; Haque, M Emdadul; Venderova, Katerina; Park, David S

Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons

小鼠原代小脑颗粒神经元死亡和退化的建模

Laaper, Matthew; Haque, Takrima; Slack, Ruth S; Jahani-Asl, Arezu

RB: An essential player in adult neurogenesis

RB:成年神经发生过程中的关键角色

Fong, Bensun C; Slack, Ruth S

Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.

酸中毒可以克服缺氧,维持线粒体功能和细胞存活

Khacho Mireille, Tarabay Michelle, Patten David, Khacho Pamela, MacLaurin Jason G, Guadagno Jennifer, Bergeron Richard, Cregan Sean P, Harper Mary-Ellen, Park David S, Slack Ruth S

OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand

OPA1依赖的嵴调节对于细胞适应代谢需求至关重要

Patten, David A; Wong, Jacob; Khacho, Mireille; Soubannier, Vincent; Mailloux, Ryan J; Pilon-Larose, Karine; MacLaurin, Jason G; Park, David S; McBride, Heidi M; Trinkle-Mulcahy, Laura; Harper, Mary-Ellen; Germain, Marc; Slack, Ruth S