日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IMiDs Augment CD3-Bispecific Antibody-Induced CD8+ T-Cell Cytotoxicity and Expansion by Enhancing IL2 Production

IMiD 通过增强 IL2 产生来增强 CD3 双特异性抗体诱导的 CD8+ T 细胞细胞毒性和扩增

Ji Li, Dionysos Slaga #, Jennifer Johnston #, Teemu T Junttila

Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer

抗LYPD1/CD3 T细胞依赖性双特异性抗体用于治疗卵巢癌

Amy A Lo, Jennifer Johnston, Ji Li, Danielle Mandikian, Maria Hristopoulos, Robyn Clark, Dorothee Nickles, Wei-Ching Liang, Kathy Hötzel, Debra Dunlap, Thinh Pham, Hao Cai, Meric Ovacik, Daniel Bravo-Perez, Elaine Mai, Dionysos Slaga, Diego Ellerman, James Ziai, Klara Totpal, Genee Lee, C Andrew Bos

Overexpression of TC-PTP in murine epidermis attenuates skin tumor formation

小鼠表皮中 TC-PTP 的过度表达可减弱皮肤肿瘤的形成

Mihwa Kim #, Liza D Morales #, Cheol Jung Lee #, Serena A Olivarez, Woo Jin Kim, Joselin Hernandez, Srinivas Mummidi, Christopher Jenkinson, Andrew T Tsin, Ik-Soon Jang, Thomas J Slaga, Dae Joon Kim

Target arm affinities determine preclinical efficacy and safety of anti-HER2/CD3 bispecific antibody

靶臂亲和力决定抗 HER2/CD3 双特异性抗体的临床前疗效和安全性

Karin Staflin, Christina L Zuch de Zafra, Leah K Schutt, Vanessa Clark, Fiona Zhong, Maria Hristopoulos, Robyn Clark, Ji Li, Mary Mathieu, Xiaocheng Chen, Jennifer Johnston, Justin Low, Ryan Ybarra, Dionysos Slaga, Jihong Yang, Meric Ovacik, Noël O Dybdal, Klara Totpal, Melissa R Junttila, Diego Ell

Acarbose improves health and lifespan in aging HET3 mice

阿卡波糖可改善衰老 HET3 小鼠的健康和寿命

David E Harrison, Randy Strong, Silvestre Alavez, Clinton Michael Astle, John DiGiovanni, Elizabeth Fernandez, Kevin Flurkey, Michael Garratt, Jonathan A L Gelfond, Martin A Javors, Moshe Levi, Gordon J Lithgow, Francesca Macchiarini, James F Nelson, Stacey J Sukoff Rizzo, Thomas J Slaga, Tim Stearn

Harnessing the gatekeepers of glucocorticoids for chemoprevention of non-melanoma skin cancer

利用糖皮质激素的调控机制预防非黑色素瘤皮肤癌

Mancha-Ramirez, Anna M; Yang, Xiaoyu; Liang, Huiyun; Junco, Jacob; Lee, Kevin P; Bovio, Sarah F; Espinoza, Maricruz; Wool, Julia; Slaga, Andrew; Glade, Daniel C; Hanes, Martha; Malik, Gunjan; Kim, Dae Joon; DiGiovanni, John; Slaga, Thomas J

The role of T-cell protein tyrosine phosphatase in epithelial carcinogenesis

T细胞蛋白酪氨酸磷酸酶在上皮癌变中的作用

Morales, Liza D; Archbold, Anna K; Olivarez, Serena; Slaga, Thomas J; DiGiovanni, John; Kim, Dae Joon

Inhibition of skin tumor promotion by TPA using a combination of topically applied ursolic acid and curcumin

局部应用熊果酸和姜黄素的组合,通过 TPA 抑制皮肤肿瘤的发生

Lisa Tremmel, Okkyung Rho, Thomas J Slaga, John DiGiovanni

Role of AMPK and PPARα in the anti-skin cancer effects of ursolic acid

AMPK 和 PPARα 在熊果酸抗皮肤癌作用中的作用

Jacob J Junco, Jiyoon Cho, Anna Mancha, Gunjan Malik, Sung-Jen Wei, Dae Joon Kim, Huiyun Liang, John DiGiovanni, Thomas J Slaga

Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing

膜近端表位促进抗 FcRH5/CD3 有效形成 T 细胞突触,并且是杀死骨髓瘤细胞的必要条件

Ji Li, Nicola J Stagg, Jennifer Johnston, Michael J Harris, Sam A Menzies, Danielle DiCara, Vanessa Clark, Maria Hristopoulos, Ryan Cook, Dionysos Slaga, Rin Nakamura, Luke McCarty, Siddharth Sukumaran, Elizabeth Luis, Zhengmao Ye, Thomas D Wu, Teiko Sumiyoshi, Dimitry Danilenko, Genee Y Lee, Klara