日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Thiopurines inhibit coronavirus Spike protein processing and incorporation into progeny virions

硫嘌呤类药物可抑制冠状病毒刺突蛋白的加工和进入子代病毒体

Eric S Pringle, Brett A Duguay, Maxwell P Bui-Marinos, Rory P Mulloy, Shelby L Landreth, Krishna Swaroop Desireddy, Stacia M Dolliver, Shan Ying, Taylor Caddell, Trinity H Tooley, Patrick D Slaine, Stephen L Bearne, Darryl Falzarano, Jennifer A Corcoran, Denys A Khaperskyy, Craig McCormick

Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation

硫嘌呤类药物可激活抗病毒未折叠蛋白反应,从而阻断甲型流感病毒糖蛋白的积累。

Patrick D Slaine ,Mariel Kleer ,Brett A Duguay ,Eric S Pringle ,Eileigh Kadijk ,Shan Ying ,Aruna Balgi ,Michel Roberge ,Craig McCormick ,Denys A Khaperskyy

Defective Influenza A Virus RNA Products Mediate MAVS-Dependent Upregulation of Human Leukocyte Antigen Class I Proteins

缺陷型甲型流感病毒RNA产物介导MAVS依赖性人类白细胞抗原I类蛋白的上调

Mir Munir A Rahim # ,Brendon D Parsons # ,Emma L Price ,Patrick D Slaine ,Becca L Chilvers ,Gregory S Seaton ,Andrew Wight ,Daniel Medina-Luna ,Sayanti Dey ,Shannen L Grandy ,Lauryn E Anderson ,Natalia Zamorano Cuervo ,Nathalie Grandvaux ,Marta M Gaglia ,Alyson A Kelvin ,Denys A Khaperskyy # ,Craig McCormick # ,Andrew P Makrigiannis #

Characterization of novel lignocellulose-degrading enzymes from the porcupine microbiome using synthetic metagenomics

利用合成宏基因组学对豪猪微生物组中新型木质纤维素降解酶进行表征

Mackenzie Thornbury, Jacob Sicheri, Patrick Slaine, Landon J Getz, Emma Finlayson-Trick, Jamie Cook, Caroline Guinard, Nicholas Boudreau, David Jakeman, John Rohde, Craig McCormick

Adaptive Mutations in Influenza A/California/07/2009 Enhance Polymerase Activity and Infectious Virion Production

流感 A/California/07/2009 中的适应性突变增强了聚合酶活性和传染性病毒体的产生

Patrick D Slaine, Cara MacRae, Mariel Kleer, Emily Lamoureux, Sarah McAlpine, Michelle Warhuus, André M Comeau, Craig McCormick, Todd Hatchette, Denys A Khaperskyy

Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication

应激颗粒诱导的真核翻译起始因子 4A 抑制剂阻断甲型流感病毒复制

Patrick D Slaine, Mariel Kleer, Nathan K Smith, Denys A Khaperskyy, Craig McCormick

Taxonomic differences of gut microbiomes drive cellulolytic enzymatic potential within hind-gut fermenting mammals

肠道微生物群的分类差异驱动后肠发酵哺乳动物的纤维素分解酶活性。

Finlayson-Trick, Emma C L; Getz, Landon J; Slaine, Patrick D; Thornbury, Mackenzie; Lamoureux, Emily; Cook, Jamie; Langille, Morgan G I; Murray, Lois E; McCormick, Craig; Rohde, John R; Cheng, Zhenyu