日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted degradation of MK2 is insufficient to block inflammatory cytokine production in human cells due to cooperativity with MK3 and MK5.

由于 MK2 与 MK3 和 MK5 存在协同作用,因此靶向降解 MK2 不足以阻止人类细胞中炎症细胞因子的产生。

Yang Bin, Fang Guoqiang, Marx Isaac, Liu Guang, Skouras Stephanie, Sharma Kirti, Walther Dirk M, Bollinger Martinez Sarah, Hubeau Cedric, Shi Yatao, De Savi Chris, Huang Xin, Huhn Annissa, Sawant Rupa, Proctor William R, Dixit Vaishali S, Dong Huijun, Weiss Matthew M, Mainolfi Nello, Slavin Anthony, Long Andrew J, Williams Juliet A, Byrne Fergus R

Pharmacokinetics and Pharmacodynamics of KT-474, a Novel Selective Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Degrader, in Healthy Adults

KT-474(一种新型选择性白细胞介素-1受体相关激酶4 (IRAK4) 降解剂)在健康成人中的药代动力学和药效学研究

Agarwal, Sagar; McDonald, Alice A; Campbell, Veronica; Chen, Dapeng; Davis, Jeff; Rong, Haojing; Mishkin, Aimee; Slavin, Anthony; Gollerkeri, Ashwin; Gollob, Jared A

Challenges in IBD Research 2024: Preclinical Human IBD Mechanisms

2024年IBD研究面临的挑战:人类IBD的临床前机制

Ciorba, Matthew A; Konnikova, Liza; Hirota, Simon A; Lucchetta, Elena M; Turner, Jerrold R; Slavin, Anthony; Johnson, Kristen; Condray, Cass D; Hong, Sungmo; Cressall, Brandon K; Pizarro, Theresa T; Hurtado-Lorenzo, Andrés; Heller, Caren A; Moss, Alan C; Swantek, Jennifer L; Garrett, Wendy S

Does MOG Ig-positive AQP4-seronegative opticospinal inflammatory disease justify a diagnosis of NMO spectrum disorder?

MOG Ig阳性AQP4血清阴性视神经脊髓炎是否足以诊断为NMO谱系障碍?

Zamvil, Scott S; Slavin, Anthony J

Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE

在实验性自身免疫性脑脊髓炎(EAE)中,髓鞘少突胶质细胞糖蛋白(MOG)的免疫优势T细胞表位位于其跨膜区和胞质区。

Shetty, Aparna; Gupta, Sheena G; Varrin-Doyer, Michel; Weber, Martin S; Prod'homme, Thomas; Molnarfi, Nicolas; Ji, Niannian; Nelson, Patricia A; Patarroyo, Juan C; Schulze-Topphoff, Ulf; Fogal, Stephen E; Forsthuber, Thomas; Sobel, Raymond A; Bernard, Claude C A; Slavin, Anthony J; Zamvil, Scott S

B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity

B细胞活化影响T细胞极化和中枢神经系统自身免疫中抗CD20 B细胞耗竭的结果

Weber, Martin S; Prod'homme, Thomas; Patarroyo, Juan C; Molnarfi, Nicolas; Karnezis, Tara; Lehmann-Horn, Klaus; Danilenko, Dimitry M; Eastham-Anderson, Jeffrey; Slavin, Anthony J; Linington, Christopher; Bernard, Claude C A; Martin, Flavius; Zamvil, Scott S

The growth factor Midkine antagonizes VEGF signaling in vitro and in vivo.

生长因子 Midkine 在体外和体内均能拮抗 VEGF 信号传导

van der Horst Edward Htun, Frank Brendon T, Chinn Lawrence, Coxon Angela, Li Shyun, Polesso Fanny, Slavin Anthony, Ruefli-Brasse Astrid, Wesche Holger