日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MK-7602: a potent multi-stage dual-targeting antimalarial

MK-7602:一种强效的多阶段双靶点抗疟药

Favuzza, Paola; Palandri, Josephine; de Lera Ruiz, Manuel; Bailey, Wendy; Boyce, Christopher W; Danziger, Andrew; Fawaz, Maria V; Kelly, Michael; Murgolo, Nicholas; Robbins, Jonathan A; Vavrek, Marissa; Zhao, Lianyun; Lei, Zhiyu; Guo, Zhuyan; Reaksudsan, Kitsanapong; Steel, Ryan W J; Hodder, Anthony N; Ngo, Anna; Dziekan, Jerzy M; Thompson, Jennifer K; Triglia, Tony; Birkinshaw, Richard W; Penington, Jocelyn Sietsma; Scally, Stephen W; Dans, Madeline G; Coyle, Rachael; Sevilleno, Nicole; Orban, Agnes; Feufack-Donfack, Lionel Brice; Popovici, Jean; Lee, Marcus C S; Papenfuss, Anthony; Lowes, Kym N; Sleebs, Brad E; McCarthy, James S; McCauley, John A; Boddey, Justin A; Olsen, David B; Cowman, Alan F

Genome-wide reconstruction of the intrinsic apoptosis pathway in Haemonchus contortus

捻转血矛线虫内在凋亡通路的全基因组重建

Shen, Yanxiang; Young, Neil D; Song, Jiangning; Sleebs, Brad E; Chang, Bill C H; Lee, Erinna F; Fairlie, Walter D; Gasser, Robin B

Exploration and Characterization of the Antimalarial Activity of Pyrimidine-2,4-Diamines for which Resistance is Mediated by the ABCI3 Transporter

探索和表征嘧啶-2,4-二胺的抗疟活性及其由ABCI3转运蛋白介导的耐药性

Mansouri, Mahta; Dans, Madeline G; Low, Zijun; Loi, Katie; Jarman, Kate E; Penington, Jocelyn S; Qiu, Deyun; Lehane, Adele M; Crespo, Benigno; Gamo, Franciso-Javier; Baud, Delphine; Brand, Stephen; Jackson, Paul F; Cowman, Alan F; Sleebs, Brad E

Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells

长期移植由人诱导多能干细胞分化而来的多系造血细胞

Ng, Elizabeth S; Sarila, Gulcan; Li, Jacky Y; Edirisinghe, Hasindu S; Saxena, Ritika; Sun, Shicheng; Bruveris, Freya F; Labonne, Tanya; Sleebs, Nerida; Maytum, Alexander; Yow, Raymond Y; Inguanti, Chantelle; Motazedian, Ali; Calvanese, Vincenzo; Capellera-Garcia, Sandra; Ma, Feiyang; Nim, Hieu T; Ramialison, Mirana; Bonifer, Constanze; Mikkola, Hanna K A; Stanley, Edouard G; Elefanty, Andrew G

Optimization and Characterization of N-Acetamide Indoles as Antimalarials That Target PfATP4

优化和表征靶向 PfATP4 的 N-乙酰胺吲哚类抗疟药

Awalt, Jon Kyle; Ooi, Zi Kang; Ashton, Trent D; Mansouri, Mahta; Calic, Petar P S; Zhou, Qingmiao; Vasanthan, Santhya; Lee, Serena; Loi, Katie; Jarman, Kate E; Penington, Jocelyn S; Qiu, Deyun; Zhang, Xinxin; Lehane, Adele M; Mao, Emma Y; Gancheva, Maria R; Wilson, Danny W; Giannangelo, Carlo; MacRaild, Christopher A; Creek, Darren J; Yeo, Tomas; Sheth, Tanaya; Fidock, David A; Churchyard, Alisje; Baum, Jake; Famodimu, Mufuliat T; Delves, Michael J; Kristan, Mojca; Stewart, Lindsay; Sutherland, Colin J; Coyle, Rachael; Jagoe, Hannah; Lee, Marcus C S; Chowdury, Mrittika; de Koning-Ward, Tania F; Baud, Delphine; Brand, Stephen; Jackson, Paul F; Cowman, Alan F; Dans, Madeline G; Sleebs, Brad E

Optimization and Characterization of the Antimalarial Activity of N-Aryl Acetamides that are Susceptible to Mutations in ROM8 and CSC1

对易受ROM8和CSC1突变影响的N-芳基乙酰胺类化合物的抗疟活性进行优化和表征

Nguyen, William; Boulet, Coralie; Dans, Madeline G; Loi, Katie; Jarman, Kate E; Barnes, Claudia B G; Yeo, Tomas; Sheth, Tanaya; Mukherjee, Partha; Chakraborty, Arnish; Famodimu, Mufuliat T; Delves, Michael J; Pollard, Harry; Sutherland, Colin J; Coyle, Rachael; Sevilleno, Nicole; Boonyalai, Nonlawat; Lee, Marcus C S; Rabie, Tayla; Birkholtz, Lyn-Marié; Baud, Delphine; Brand, Stephen; Chowdury, Mrittika; de Koning-Ward, Tania F; Fidock, David A; Gilson, Paul R; Sleebs, Brad E

Characterizing the quick-killing mechanism of action of azithromycin analogs against malaria parasites

阐明阿奇霉素类似物对疟原虫的快速杀灭机制

Mao, Emma Y; Nguyen, William; Jana, Gouranga P; Maity, Bikash C; Pazicky, Samuel; Giannangelo, Carlo; Reader, Janette; Famodimu, Mufuliat T; Birkholtz, Lyn-Marie; Delves, Michael J; Creek, Darren J; Bozdech, Zbynek; Laleu, Benoît; Burrows, Jeremy N; Sleebs, Brad E; Gancheva, Maria R; Wilson, Danny W

Deconvolution of the On-Target Activity of Plasmepsin V Peptidomimetics in Plasmodium falciparum Parasites

疟原虫中疟原虫蛋白酶V肽模拟物靶向活性的解卷积

Wenyin Su,William Nguyen,Ghizal Siddiqui,Jerzy M Dziekan,Danushka Marapana,Jocelyn Sietsma Penington,Somya Mehra,Zahra Razook,Kirsty McCann,Anna Ngo,Kate E Jarman,Alyssa E Barry,Anthony T Papenfuss,Paul R Gilson,Darren John Creek,Alan F Cowman,Brad E Sleebs,Madeline G Dans

Structure-activity analysis of imino-pyrimidinone-fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors

亚氨基嘧啶酮稠合吡咯烷的结构活性分析有助于开发双重血浆素V和血浆素X抑制剂。

Hodder, Anthony N; Sleebs, Brad E; Adams, Greg; Rezazadeh, Sina; Ngo, Anna; Jarman, Kate; Scally, Stephen; Czabotar, Peter; Wang, Hongwu; McCauley, John A; Olsen, David B; Cowman, Alan F

A review of natural products as a source of next-generation drugs against apicomplexan parasites

天然产物作为下一代抗顶复门寄生虫药物来源的综述

Mao, Emma Y; Page, Stephen W; Sleebs, Brad E; Gancheva, Maria R; Wilson, Danny W