日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immune imbalance between T helper 1, T helper 17 and regulatory T cells fuels amyotrophic lateral sclerosis pathogenesis: disease trajectory, diagnosis and therapeutic implications

T辅助细胞1、T辅助细胞17和调节性T细胞之间的免疫失衡是肌萎缩侧索硬化症发病机制的关键因素:疾病发展轨迹、诊断和治疗意义

Sligar, Chloe; Sluyter, Ronald; Ooi, Lezanne

Lipid Dependence of CYP3A4 Activity in Nanodiscs

纳米盘中CYP3A4活性的脂质依赖性

Denisov, Ilia G; Grinkova, Yelena V; Sligar, Stephen G

Protocol for Nanodisc single-molecule pull-down assay to detect protein-lipid interactions.

用于检测蛋白质-脂质相互作用的纳米盘单分子下拉试验方案。

Reyes-Ordoñez Adriana, Shree Shweta, Sligar Stephen G, Chen Jie

Cold exposure stimulates cross-tissue metabolic rewiring to fuel glucose-dependent thermogenesis in brown adipose tissue

寒冷刺激可促进棕色脂肪组织中葡萄糖依赖性产热的跨组织代谢重编程。

Cutler, Harry B; Jall-Rogg, Sigrid; Thillainadesan, Senthil; Cooke, Kristen C; Masson, Stewart W C; Sligar, James M; Crowston, Jonathan G; Carroll, Luke; Stöckli, Jacqueline; James, David E; Madsen, Søren

Low- and high-dose post-transplant cyclophosphamide attenuates graft-versus-host disease with distinct effects on PD-1+ T cell subsets

移植后低剂量和高剂量环磷酰胺均可减轻移植物抗宿主病,且对PD-1+ T细胞亚群的影响各不相同。

Sligar, Chloe; Jacobs, Miles J; Elhage, Amal; Sluyter, Ronald; Watson, Debbie

Nanodisc single-molecule pulldown to study lipid-protein interactions

利用纳米盘单分子下拉技术研究脂质-蛋白质相互作用

Reyes-Ordoñez, Adriana; Shree, Shweta; Singh, Nilmani; Sligar, Stephen G; Chen, Jie

Adeno-associated viral vectors encoding anti-P2X7 nanobodies reduce graft-versus-host disease in a humanised mouse model

编码抗P2X7纳米抗体的腺相关病毒载体可降低人源化小鼠模型中的移植物抗宿主病。

Elhage, Amal; Hadaya, Janna H; Sligar, Chloe; Watson, Debbie; Adriouch, Sahil; Sluyter, Ronald

Observation of Ras protein GTP hydrolysis and conformation change by freeze-trap serial X-ray crystallography

利用冷冻阱连续X射线晶体衍射法观察Ras蛋白GTP水解和构象变化

Shree, Shweta; McLean, Mark A; Stephen, Andrew G; Sligar, Stephen G; Kawamura, Takashi; Sakisaka, Wakako; Makino, Yoshiteru; Matsumoto, Shigeyuki; Yoshikawa, Yoko; Hasegawa, Kazuya; Shima, Fumi; Kumasaka, Takashi

Selective α-Hydroxyketone Formation and Subsequent C-C Bond Cleavage by Cytochrome P450 Monooxygenase Enzymes

细胞色素P450单加氧酶选择性地生成α-羟基酮并随后断裂C-C键

Lee, Joel H Z; Coleman, Tom; Mclean, Mark A; Podgorski, Matthew N; Hayball, Eva F; Stone, Isobella S J; Bruning, John B; Whelan, Fiona; Voss, James J De; Sligar, Stephen G; Bell, Stephen G

Nanodiscs for the study of membrane proteins

用于研究膜蛋白的纳米盘

Denisov, Ilia G; Sligar, Stephen G