日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanisms of Acquired Resistance to Trastuzumab Emtansine in Breast Cancer Cells

乳腺癌细胞对曲妥珠单抗获得性耐药的机制

Guangmin Li, Jun Guo, Ben-Quan Shen, Daniela Bumbaca Yadav, Mark X Sliwkowski, Lisa M Crocker, Jennifer A Lacap, Gail D Lewis Phillips

High cell-surface density of HER2 deforms cell membranes

HER2 在细胞表面的高密度导致细胞膜变形

Inhee Chung, Mike Reichelt, Lily Shao, Robert W Akita, Hartmut Koeppen, Linda Rangell, Gabriele Schaefer, Ira Mellman, Mark X Sliwkowski

Dual targeting of HER2-positive cancer with trastuzumab emtansine and pertuzumab: critical role for neuregulin blockade in antitumor response to combination therapy

曲妥珠单抗 emtansine 和帕妥珠单抗双重靶向 HER2 阳性癌症:神经调节蛋白阻断在联合治疗的抗肿瘤反应中起着关键作用

Gail D Lewis Phillips, Carter T Fields, Guangmin Li, Donald Dowbenko, Gabriele Schaefer, Kathy Miller, Fabrice Andre, Howard A Burris 3rd, Kathy S Albain, Nadia Harbeck, Veronique Dieras, Diana Crivellari, Liang Fang, Ellie Guardino, Steven R Olsen, Lisa M Crocker, Mark X Sliwkowski

Personalized drug combinations to overcome trastuzumab resistance in HER2-positive breast cancer

针对HER2阳性乳腺癌的曲妥珠单抗耐药性,采用个性化药物组合进行治疗

Vu, Thuy; Sliwkowski, Mark X; Claret, Francois X

Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab

重组单克隆抗体的人源化生产治疗性 HER 二聚化抑制剂帕妥珠单抗

Camellia W Adams, David E Allison, Kelly Flagella, Leonard Presta, Janet Clarke, Noel Dybdal, Kathleen McKeever, Mark X Sliwkowski

Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin

ErbB2的内吞作用和分选以及抗癌药物曲妥珠单抗和格尔德霉素的作用位点

Austin, Cary D; De Mazière, Ann M; Pisacane, Paul I; van Dijk, Suzanne M; Eigenbrot, Charles; Sliwkowski, Mark X; Klumperman, Judith; Scheller, Richard H

Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2

人类雪旺细胞的轴突诱导有丝分裂涉及 heregulin 和 p185erbB2

Morrissey, T K; Levi, A D; Nuijens, A; Sliwkowski, M X; Bunge, R P

The influence of heregulins on human Schwann cell proliferation

赫格林对人雪旺细胞增殖的影响

Levi, A D; Bunge, R P; Lofgren, J A; Meima, L; Hefti, F; Nikolics, K; Sliwkowski, M X

Serological evaluation of Escherichia coli-expressed human T-cell leukemia virus type I env, gag p24, and tax proteins

对大肠杆菌表达的人类T细胞白血病病毒I型env、gag p24和tax蛋白进行血清学评价

Coates, S R; Harris, A J; Parkes, D L; Smith, C M; Liu, H L; Akita, R W; Ferrer, M M; Sampson, E K; Brandis, J W; Sliwkowski, M X