日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Liver-Specific Nanoparticle-Mediated Delivery and MMP-Triggered Release of Veratridine to Effectively Target Metastatic Colorectal Cancer.

利用肝脏特异性纳米颗粒介导递送和MMP触发释放藜芦碱,有效靶向转移性结直肠癌。

Hasan Mahadi, Eikanger Morgan, Sane Sanam, Wijewardhane Krishantha S K, Slunecka John L, Freeling Jessica, Rezvani Khosrow, Sereda Grigoriy

Breast Cancer Polygenic Risk Score Validation and Effects of Variable Imputation

乳腺癌多基因风险评分的验证及变量插补的影响

Beck, Jeffrey J; Slunecka, John L; Johnson, Brandon N; Van Asselt, Austin J; Finnicum, Casey T; Ageton, Cheryl; Krie, Amy; Nickles, Heidi; Cowan, Kenneth; Maxwell, Jessica; Boomsma, Dorret I; de Geus, Eco; Ehli, Erik A; Hottenga, Jouke-Jan

Veratridine, a plant-derived alkaloid, suppresses the hyperactive Rictor-mTORC2 pathway: a new targeted therapy for primary and metastatic colorectal cancer

藜芦碱是一种植物来源的生物碱,可抑制过度活跃的 Rictor-mTORC2 通路:一种针对原发性和转移性结直肠癌的新型靶向疗法

Morgan M Eikanger, Sanam Sane, Kate S Schraufnagel, John L Slunecka, Rashaun A Potts, Jessica Freeling, Grigoriy Sereda, Bakhtiyor Rasulev, Reed L Brockstein, M A Bashar Emon, M Taher A Saif, Khosrow Rezvani

A phase 1 evaluation of the safety and tolerability of niraparib in combination with everolimus in advanced ovarian and breast cancers

一项评估尼拉帕尼联合依维莫司治疗晚期卵巢癌和乳腺癌的安全性和耐受性的I期临床试验

Starks, David; Rojas-Espaillat, Luis; Meissner, Tobias; Elsey, Rachel; Xu, Bing; Koenen, Maria; Feng, Shelley; VanOosbree, Annika; Slunecka, John; Lee, John; Williams, Casey B

Implementation and implications for polygenic risk scores in healthcare

多基因风险评分在医疗保健中的应用及其意义

Slunecka, John L; van der Zee, Matthijs D; Beck, Jeffrey J; Johnson, Brandon N; Finnicum, Casey T; Pool, René; Hottenga, Jouke-Jan; de Geus, Eco J C; Ehli, Erik A

UBXN2A enhances CHIP-mediated proteasomal degradation of oncoprotein mortalin-2 in cancer cells

UBXN2A 增强癌细胞中 CHIP 介导的蛋白酶体癌蛋白 mortalin-2 降解

Sanam Sane, Andre Hafner, Rekha Srinivasan, Daniall Masood, John L Slunecka, Collin J Noldner, Alex D Hanson, Taylor Kruisselbrink, Xuejun Wang, Yiyang Wang, Jun Yin, Khosrow Rezvani