日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ENU-induced phenovariance in mice: inferences from 587 mutations

ENU诱导的小鼠表型变异:来自587个突变的推断

Arnold, Carrie N; Barnes, Michael J; Berger, Michael; Blasius, Amanda L; Brandl, Katharina; Croker, Ben; Crozat, Karine; Du, Xin; Eidenschenk, Celine; Georgel, Philippe; Hoebe, Kasper; Huang, Hua; Jiang, Zhengfan; Krebs, Philippe; La Vine, Diantha; Li, Xiaohong; Lyon, Stephen; Moresco, Eva Marie Y; Murray, Anne R; Popkin, Daniel L; Rutschmann, Sophie; Siggs, Owen M; Smart, Nora G; Sun, Lei; Tabeta, Koichi; Webster, Victoria; Tomisato, Wataru; Won, Sungyong; Xia, Yu; Xiao, Nengming; Beutler, Bruce

Rapid identification of a disease allele in mouse through whole genome sequencing and bulk segregation analysis

通过全基因组测序和群体分离分析快速鉴定小鼠致病等位基因

Arnold, Carrie N; Xia, Yu; Lin, Pei; Ross, Charles; Schwander, Martin; Smart, Nora G; Müller, Ulrich; Beutler, Bruce

A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha.

Ikbkg 的突变会导致免疫缺陷,但不会损害 IkappaB α 的降解

Siggs Owen M, Berger Michael, Krebs Philippe, Arnold Carrie N, Eidenschenk Celine, Huber Christoph, Pirie Elaine, Smart Nora G, Khovananth Kevin, Xia Yu, McInerney Gerald, Karlsson Hedestam Gunilla B, Nemazee David, Beutler Bruce

Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function

携带Dock7基因突变的小鼠表现出全身性色素减退和白斑,但神经功能正常。

Blasius, Amanda L; Brandl, Katharina; Crozat, Karine; Xia, Yu; Khovananth, Kevin; Krebs, Philippe; Smart, Nora G; Zampolli, Antonella; Ruggeri, Zaverio M; Beutler, Bruce A

The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease

Tpl2 突变 Sluggish 会损害 I 型干扰素的产生,并增加对 B 族链球菌疾病的易感性。

Xiao, Nengming; Eidenschenk, Celine; Krebs, Philippe; Brandl, Katharina; Blasius, Amanda L; Xia, Yu; Khovananth, Kevin; Smart, Nora G; Beutler, Bruce

Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

胰岛β细胞中Smad7的条件性表达会破坏TGF-β信号传导并诱发可逆性糖尿病

Smart, Nora G; Apelqvist, Asa A; Gu, Xueying; Harmon, Erin B; Topper, James N; MacDonald, Raymond J; Kim, Seung K