A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
大规模化学修饰筛选确定了生成具有高活性、高稳定性和低毒性的siRNA的设计规则。
期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkp106
Bramsen, Jesper B; Laursen, Maria B; Nielsen, Anne F; Hansen, Thomas B; Bus, Claus; Langkjaer, Niels; Babu, B Ravindra; Højland, Torben; Abramov, Mikhail; Van Aerschot, Arthur; Odadzic, Dalibor; Smicius, Romualdas; Haas, Jens; Andree, Cordula; Barman, Jharna; Wenska, Malgorzata; Srivastava, Puneet; Zhou, Chuanzheng; Honcharenko, Dmytro; Hess, Simone; Müller, Elke; Bobkov, Georgii V; Mikhailov, Sergey N; Fava, Eugenio; Meyer, Thomas F; Chattopadhyaya, Jyoti; Zerial, Marino; Engels, Joachim W; Herdewijn, Piet; Wengel, Jesper; Kjems, Jørgen
