日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Class switched bovine ultralong CDR H3 amplicons versus canonical in immune and non-immune tissues

免疫组织和非免疫组织中牛超长CDR H3扩增子与经典扩增子的类别转换

Hissen, Karina L; Sheppard, Morgan; Ott, Jeannine A; Landrock, Kerstin K; Whitley, Casey; Ebert, Nicholas; Horton, J M Cody; Glenn, Nicole A; Jung, Yoonsung; Smider, Vaughn V; Criscitiello, Michael F

HIV envelope trimers and gp120 as immunogens to induce broadly neutralizing antibodies in cows

HIV 包膜三聚体和 gp120 作为免疫原在奶牛体内诱导广泛中和抗体

Pilar X Altman, Mara Parren, Huldah Sang, Gabriel Ozorowski, Wen-Hsin Lee, Vaughn V Smider, Ian A Wilson, Andrew B Ward, Waithaka Mwangi, Dennis R Burton, Devin Sok1

Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire

用 HIV 包膜三聚体免疫奶牛,可产生针对超长 CDRH3 库中 V2 顶端的广谱中和抗体。

Altman, Pilar X; Ozorowski, Gabriel; Stanfield, Robyn L; Haakenson, Jeremy; Appel, Michael; Parren, Mara; Lee, Wen-Hsin; Sang, Huldah; Woehl, Jordan; Saye-Francisco, Karen; Joyce, Collin; Song, Ge; Porter, Katelyn; Landais, Elise; Andrabi, Raiees; Wilson, Ian A; Ward, Andrew B; Mwangi, Waithaka; Smider, Vaughn V; Burton, Dennis R; Sok, Devin

Evolution of immunogenetic components encoding ultralong CDR H3

编码超长CDR H3的免疫遗传成分的进化

Ott, Jeannine A; Mitchell, Christian; Sheppard, Morgan; Deiss, Thad C; Horton, J M Cody; Haakenson, Jeremy K; Huang, Ruiqi; Kelley, Abigail R; Davis, Brian W; Derr, James N; Smider, Vaughn V; Criscitiello, Michael F

Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators

具有免疫球蛋白调节剂的 T 细胞钾通道 Kv1.3 的结构

Purushotham Selvakumar #, Ana I Fernández-Mariño #, Nandish Khanra, Changhao He, Alice J Paquette, Bing Wang, Ruiqi Huang, Vaughn V Smider, William J Rice, Kenton J Swartz, Joel R Meyerson

Evolution of surrogate light chain in tetrapods and the relationship between lengths of CDR H3 and VpreB tails

四足动物替代轻链的演化以及CDR H3和VpreB尾部长度之间的关系

Ott, Jeannine A; Haakenson, Jeremy K; Kelly, Abigail R; Christian, Claire; Criscitiello, Michael F; Smider, Vaughn V

Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity

挤奶:牛衍生的嵌合超长 CDR-H3 抗体及其针对表皮生长因子受体的工程化 CDR-H3 旋钮对应物引发强效 NK 细胞介导的细胞毒性

Lukas Pekar, Daniel Klewinghaus, Paul Arras, Stefania C Carrara, Julia Harwardt, Simon Krah, Desislava Yanakieva, Lars Toleikis, Vaughn V Smider, Harald Kolmar, Stefan Zielonka

Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity

牛源嵌合超长CDR-H3抗体及其工程化CDR-H3-仅Knobbody对应物靶向表皮生长因子受体,可诱导强效NK细胞介导的细胞毒性

Lukas Pekar,Daniel Klewinghaus,Paul Arras,Stefania C Carrara,Julia Harwardt,Simon Krah,Desislava Yanakieva,Lars Toleikis,Vaughn V Smider,Harald Kolmar,Stefan Zielonka

Formation of ultralong DH regions through genomic rearrangement

通过基因组重排形成超长DH区

Smider, Brevin A; Smider, Vaughn V

Immunogenetic factors driving formation of ultralong VH CDR3 in Bos taurus antibodies

免疫遗传因素驱动牛抗体中超长VH CDR3的形成

Deiss, Thaddeus C; Vadnais, Melissa; Wang, Feng; Chen, Patricia L; Torkamani, Ali; Mwangi, Waithaka; Lefranc, Marie-Paule; Criscitiello, Michael F; Smider, Vaughn V