日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Increased Neuronal Expression of the Early Endosomal Adaptor APPL1 Replicates Alzheimer's Disease-Related Endosomal and Synaptic Dysfunction with Cholinergic Neurodegeneration.

早期内体衔接蛋白 APPL1 的神经元表达增加,可重现阿尔茨海默病相关的内体和突触功能障碍以及胆碱能神经退行性变

Jiang Ying, Sachdeva Kuldeep, Goulbourne Chris N, Berg Martin J, Peddy James, Stavrides Philip H, Pensalfini Anna, Pawlik Monika, Malampati Sandeep, Whyte Lauren, Basavarajappa Balapal S, Subbanna Shivakumar, Bleiwas Cynthia, Smiley John F, Mathews Paul M, Nixon Ralph A

Increased neuronal expression of the early endosomal adaptor APPL1 replicates Alzheimer's Disease-related endosomal and synaptic dysfunction with cholinergic neurodegeneration

早期内体衔接蛋白APPL1在神经元中的表达增加,会重现阿尔茨海默病相关的内体和突触功能障碍以及胆碱能神经退行性变。

Jiang, Ying; Sachdeva, Kuldeep; Goulbourne, Chris N; Berg, Martin J; Peddy, James; Stavrides, Philip H; Pensalfini, Anna; Pawlik, Monika; Malampati, Sandeep; Whyte, Lauren; Basavarajappa, Balapal S; Shivakumar, Subbanna; Bleiwas, Cynthia; Smiley, John F; Mathews, Paul M; Nixon, Ralph A

Developmental alcohol exposure is exhausting: Sleep and the enduring consequences of alcohol exposure during development

发育期酒精暴露令人疲惫不堪:睡眠及发育期酒精暴露的持久后果

Wilson, Donald A; Sullivan, Regina M; Smiley, John F; Saito, Mariko; Raineki, Charlis

Estimates of total neuron number show that neonatal ethanol causes immediate and lasting neuron loss in cortical and subcortical areas

对神经元总数的估计表明,新生儿期乙醇会导致皮层和皮层下区域神经元立即且持续丢失。

Smiley, John F; Bleiwas, Cynthia; Marino, Brandon M; Vaddi, Prerana; Canals-Baker, Stefanie; Wilson, Donald A; Saito, Mariko

The Thalamocortical Circuit of Auditory Mismatch Negativity

听觉失配负波的丘脑皮质回路

Lakatos, Peter; O'Connell, Monica N; Barczak, Annamaria; McGinnis, Tammy; Neymotin, Samuel; Schroeder, Charles E; Smiley, John F; Javitt, Daniel C

Effects of neonatal ethanol on cerebral cortex development through adolescence.

新生儿期乙醇对青春期大脑皮层发育的影响

Smiley John F, Bleiwas Cynthia, Masiello Kurt, Petkova Eva, Betz Judith, Hui Maria, Wilson Donald A, Saito Mariko

Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors

神经丝轻链与GluN1的相互作用调节神经传递和精神分裂症相关行为

Yuan, Aidong; Veeranna; Sershen, Henry; Basavarajappa, Balapal S; Smiley, John F; Hashim, Audrey; Bleiwas, Cynthia; Berg, Martin; Guifoyle, David N; Subbanna, Shivakumar; Darji, Sandipkumar; Kumar, Asok; Rao, Mala V; Wilson, Donald A; Julien, Jean-Pierre; Javitt, Daniel C; Nixon, Ralph A

Cystatin C prevents neuronal loss and behavioral deficits via the endosomal pathway in a mouse model of down syndrome

胱抑素C通过内体途径在唐氏综合征小鼠模型中预防神经元丢失和行为缺陷

Kaur, Gurjinder; Gauthier, Sebastien A; Perez-Gonzalez, Rocio; Pawlik, Monika; Singh, Amol Bikram; Cosby, Benjamin; Mohan, Panaiyur S; Smiley, John F; Levy, Efrat

Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF

在唐氏综合征小鼠模型中,部分降低BACE1表达可阻断阿尔茨海默病相关的内体异常和胆碱能神经退行性变:APP-CTF的作用

Jiang, Ying; Rigoglioso, Andrew; Peterhoff, Corrinne M; Pawlik, Monika; Sato, Yutaka; Bleiwas, Cynthia; Stavrides, Philip; Smiley, John F; Ginsberg, Stephen D; Mathews, Paul M; Levy, Efrat; Nixon, Ralph A

Reduced GABA neuron density in auditory cerebral cortex of subjects with major depressive disorder

重度抑郁症患者听觉大脑皮层中GABA能神经元密度降低

Smiley, John F; Hackett, Troy A; Bleiwas, Cynthia; Petkova, Eva; Stankov, Aleksandar; Mann, J John; Rosoklija, Gorazd; Dwork, Andrew J