日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An MIEN1-based hexamer peptide (LA3IK) inhibits EGF-driven oncogenic signaling in prostate cancer by disrupting EGFR-ERBB2 heterodimerization

一种基于MIEN1的六聚体肽(LA3IK)通过破坏EGFR-ERBB2异二聚体化来抑制前列腺癌中EGF驱动的致癌信号传导。

Tripathi, Amit K; Ahamad, Nafees; Tyagi, Antariksh; Quainoo, Benedicta; Smith, Adam W; Singh, Pragati; Sabnis, Nirupama; Vishwanatha, Jamboor K

Regulation of receptor tyrosine kinase hetero-interactions

受体酪氨酸激酶异源相互作用的调控

Smith, Adam W; Barrera, Francisco N

Building a dynamic model for EGFR-family dimerization using quantitative, live-cell fluorescence methods

利用定量活细胞荧光方法构建EGFR家族二聚化的动态模型

Burns, Eric A; Matyas, Brent; Lidke, Diane S; Smith, Adam W

Phosphatidylinositol 4,5-bisphosphate drives the formation of EGFR and EphA2 complexes.

磷脂酰肌醇 4,5-二磷酸酯驱动 EGFR 和 EphA2 复合物的形成

Singh Pradeep Kumar, Rybak Jennifer A, Schuck Ryan J, Sahoo Amita R, Buck Matthias, Barrera Francisco N, Smith Adam W

The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cells.

β2-肾上腺素能受体与人类癌细胞中的CXCR4多聚体结合

Liang Junyi, Seghiri Mohamed, Singh Pradeep Kumar, Seo Hyeon Gyu, Lee Ji Yeong, Jo Yoonjung, Song Yong Bhum, Park Chulo, Zalicki Piotr, Jeong Jae-Yeon, Huh Won-Ki, Caculitan Niña G, Smith Adam W

Analysis of EGFR binding hotspots for design of new EGFR inhibitory biologics

分析EGFR结合热点以设计新型EGFR抑制性生物制剂

Tydings, Claiborne W; Singh, Bhuminder; Smith, Adam W; Ledwitch, Kaitlyn V; Brown, Benjamin P; Lovly, Christine M; Walker, Allison S; Meiler, Jens

HER4 is a high-affinity dimerization partner for all EGFR/HER/ErbB family proteins

HER4是所有EGFR/HER/ErbB家族蛋白的高亲和力二聚化伴侣。

Singh, Pradeep Kumar; Kim, Soyeon; Smith, Adam W

The Oligomeric State of Vasorin in the Plasma Membrane Measured Non-Invasively by Quantitative Fluorescence Fluctuation Spectroscopy

利用定量荧光波动光谱法无创测量质膜中血管加压素的寡聚状态

Liang, Junyi; Smith, Adam W

Time-resolved live-cell spectroscopy reveals EphA2 multimeric assembly

时间分辨活细胞光谱揭示了EphA2多聚体的组装

Shi, Xiaojun; Lingerak, Ryan; Herting, Cameron J; Ge, Yifan; Kim, Soyeon; Toth, Paul; Wang, Wei; Brown, Benjamin P; Meiler, Jens; Sossey-Alaoui, Khalid; Buck, Matthias; Himanen, Juha; Hambardzumyan, Dolores; Nikolov, Dimitar B; Smith, Adam W; Wang, Bingcheng

Single-molecule FRET imaging of GPCR dimers in living cells

利用单分子FRET成像技术对活细胞中的GPCR二聚体进行成像

Asher, Wesley B; Geggier, Peter; Holsey, Michael D; Gilmore, Grant T; Pati, Avik K; Meszaros, Jozsef; Terry, Daniel S; Mathiasen, Signe; Kaliszewski, Megan J; McCauley, Mitchell D; Govindaraju, Alekhya; Zhou, Zhou; Harikumar, Kaleeckal G; Jaqaman, Khuloud; Miller, Laurence J; Smith, Adam W; Blanchard, Scott C; Javitch, Jonathan A