日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Titin's P-zone domains A164-167 are essential for thick filament structural arrangement.

肌联蛋白的 P 区结构域 A164-167 对粗丝的结构排列至关重要。

Hoover Browne Catherine, Han Seong-Won, Farman Gerrie P, Smith John E, Kolb Justin, Gohlke Jochen, Langlais Paul R, Tonino Paola, Methawasin Mei, van der Pijl Robbert, Granzier Henk

Reducing Granules Without Splicing Restoration Alleviates RBM20 Cardiomyopathy

减少颗粒而不进行剪接修复可缓解RBM20心肌病

Methawasin, Mei; Zhang, Yanghai; Gregorich, Zachery R; He, Yaqin; Liu, Chunling; Muldoon, Julia; Hourani, Zaynab; Smith, John E 3rd; Granzier, Henk; Guo, Wei

Importance of N2BA Titin in Maintaining Cardiac Homeostasis and Its Role in Dilated Cardiomyopathy

N2BA 肌联蛋白在维持心脏稳态中的重要性及其在扩张型心肌病中的作用

van der Pijl, Robbert; Nusayr, Eyad; Strom, Joshua; Slater, Rebecca; Gohlke, Jochen; Hourani, Zaynab; Saripalli, Chandra; Kolb, Justin; Hermanson, Kyra; Brynnel, Odhin; Smith, John E 3rd; Labeit, Siegfried; Methawasin, Mei; Granzier, Henk

Rbm20 antisense oligonucleotides alleviate diastolic dysfunction in a mouse model of cardiometabolic heart failure (HFpEF)

Rbm20 反义寡核苷酸可缓解小鼠心血管代谢性心力衰竭 (HFpEF) 模型中的舒张功能障碍

Methawasin, Mei; Meinke, Stefan; Radke, Michael H; Farman, Gerrie P; Hourani, Zaynab; Smith, John E 3rd; Guo, Wei; Granzier, Henk; Gotthardt, Michael

In vivo gene editing of CAMKIID: out with the bad and in with the good

CAMKIID的体内基因编辑:去除有害成分,引入有益成分

Smith, John E 3rd; Granzier, Henk

The number of Z-repeats and super-repeats in nebulin greatly varies across vertebrates and scales with animal size

神经纤维蛋白中Z重复序列和超重复序列的数量在脊椎动物中差异很大,并且与动物体型呈正相关。

Gohlke, Jochen; Tonino, Paola; Lindqvist, Johan; Smith, John E; Granzier, Henk

Fine mapping titin's C-zone: Matching cardiac myosin-binding protein C stripes with titin's super-repeats

精细绘制肌联蛋白C区图谱:将心肌肌球蛋白结合蛋白C条纹与肌联蛋白的超重复序列进行匹配

Tonino, Paola; Kiss, Balazs; Gohlke, Jochen; Smith, John E 3rd; Granzier, Henk

Novex-3, the tiny titin of muscle

Novex-3,肌肉中的微小肌联蛋白

Kellermayer, Dalma; Smith, John E 3rd; Granzier, Henk

Phosphorylating Titin's Cardiac N2B Element by ERK2 or CaMKIIδ Lowers the Single Molecule and Cardiac Muscle Force

ERK2 或 CaMKIIδ 对肌联蛋白心脏 N2B 元件的磷酸化会降低单分子水平和心肌收缩力。

Perkin, John; Slater, Rebecca; Del Favero, Giorgia; Lanzicher, Thomas; Hidalgo, Carlos; Anderson, Brian; Smith, John E 3rd; Sbaizero, Orfeo; Labeit, Siegfried; Granzier, Henk

Cardiomyocyte-specific deletion of leptin receptors causes lethal heart failure in Cre-recombinase-mediated cardiotoxicity

心肌细胞特异性地删除瘦素受体会导致 Cre 重组酶介导的心脏毒性导致致命的心力衰竭

Michael E Hall, Grant Smith, John E Hall, David E Stec