A shear stress-responsive pathway in monocytes drives cardiopulmonary bypass-induced inflammation via spectrin/RAF1/store-operated calcium entry.
单核细胞中的剪切应力反应通路通过血影蛋白/RAF1/储存操纵的钙离子内流驱动体外循环诱导的炎症。
期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2025.116903
Li Weiming, Tu Lan N, Hsieh Lance, Smith Julian R, Yeh Yi-Ting, Sinyagin Anthony, Evans Eric G B, Ghassemian Majid, Timms Andrew, Charette Kevin, Mauchley David, McMullan Michael, Bohuta Lyubomyr, Greene Christina, Regier Mary C, Del Alamo Juan Carlos, Savan Ram, Nigam Vishal
细胞生物学
单核细胞
RAF1
Immunology/Inflammation
炎症
