日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of small molecule antagonists of chemokine receptor CXCR6 that arrest tumor growth in SK-HEP-1 mouse xenografts as a model of hepatocellular carcinoma

发现趋化因子受体CXCR6的小分子拮抗剂可抑制SK-HEP-1小鼠异种移植瘤(肝细胞癌模型)的肿瘤生长。

Peddibhotla, Satyamaheshwar; Hershberger, Paul M; Jason Kirby, R; Sugarman, Eliot; Maloney, Patrick R; Hampton Sessions, E; Divlianska, Daniela; Morfa, Camilo J; Terry, David; Pinkerton, Anthony B; Smith, Layton H; Malany, Siobhan

Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization

将抗疟疾氨基喹啉类药物及相关化合物重新用于治疗视网膜新生血管

McAnally, Danielle; Siddiquee, Khandaker; Gomaa, Ahmed; Szabo, Andras; Vasile, Stefan; Maloney, Patrick R; Divlianska, Daniela B; Peddibhotla, Satyamaheshwar; Morfa, Camilo J; Hershberger, Paul; Falter, Rebecca; Williamson, Robert; Terry, David B; Farjo, Rafal; Pinkerton, Anthony B; Qi, Xiaping; Quigley, Judith; Boulton, Michael E; Grant, Maria B; Smith, Layton H

Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus

(E)-2-((1,4-二甲基哌嗪-2-亚基)氨基)-5-硝基-N-苯基苯甲酰胺,ML336 的开发:新型 2-脒基苯基苯甲酰胺类化合物作为委内瑞拉马脑炎病毒的强效抑制剂

Schroeder, Chad E; Yao, Tuanli; Sotsky, Julie; Smith, Robert A; Roy, Sudeshna; Chu, Yong-Kyu; Guo, Haixun; Tower, Nichole A; Noah, James W; McKellip, Sara; Sosa, Melinda; Rasmussen, Lynn; Smith, Layton H; White, E Lucile; Aubé, Jeffrey; Jonsson, Colleen B; Chung, Donghoon; Golden, Jennifer E

Exendin-4 improves cardiac function in mice overexpressing monocyte chemoattractant protein-1 in cardiomyocytes.

Exendin-4 可改善心肌细胞中单核细胞趋化蛋白-1 过表达小鼠的心脏功能

Younce Craig W, Niu Jianli, Ayala Jennifer, Burmeister Melissa A, Smith Layton H, Kolattukudy Pappachan, Ayala Julio E

Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1

设计、合成和评价苯并异噻唑酮类化合物作为PHOSPHO1选择性抑制剂

Bravo, Yalda; Teriete, Peter; Dhanya, Raveendra-Panickar; Dahl, Russell; Lee, Pooi San; Kiffer-Moreira, Tina; Ganji, Santhi Reddy; Sergienko, Eduard; Smith, Layton H; Farquharson, Colin; Millán, José Luis; Cosford, Nicholas D P

Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production

Apelin可预防血管紧张素II诱导的心血管纤维化,并降低1型纤溶酶原激活物抑制剂的生成。

Siddiquee, Khandaker; Hampton, Jessica; Khan, Susan; Zadory, Dan; Gleaves, Linda; Vaughan, Douglas E; Smith, Layton H

Chemical biology strategy reveals pathway-selective inhibitor of NF-kappaB activation induced by protein kinase C.

化学生物学策略揭示了蛋白激酶 C 诱导的 NF-κB 激活的通路选择性抑制剂

Shi Ranxin, Re Daniel, Dudl Eric, Cuddy Michael, Okolotowicz Karl J, Dahl Russell, Su Ying, Hurder Andrew, Kitada Shinichi, Peddibhotla Satyamaheshwar, Roth Gregory P, Smith Layton H, Kipps Thomas J, Cosford Nicholas, Cashman John, Reed John C