日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson's disease: A DNA co-methylation network analysis

帕金森病神经精神和认知症状的表观遗传学见解:DNA共甲基化网络分析

Harvey, Joshua; Smith, Adam R; Weymouth, Luke S; Smith, Rebecca G; Castanho, Isabel; Hubbard, Leon; Creese, Byron; Bresner, Catherine; Williams, Nigel; Pishva, Ehsan; Lunnon, Katie

Comparison of two automated ApoE4 proteotype immunoassays

两种自动化ApoE4蛋白型免疫测定的比较

Wadop, Yannick N; Bernal, Rebecca; Njamnshi, Wepnyu Y; Satizabal, Claudia L; Beiser, Alexa; Ruiz, Agustin; Njamnshi, Alfred K; Vasan, Ramachandran S; Seshadri, Sudha; Himali, Jayandra Jung; Fongang, Bernard; Huang, Xin; Wang, Jennica; Kagawa, Yoshiteru; Belaidi, Abdel Ali; Gu, Ben J; Masters, Colin L; Weymouth, Luke; Smith, Rebecca G; Smith, Adam R; Mill, Jonathan; Jeffries, Aaron; Pishva, Ehsan; Lunnon, Katie; Figdore, Daniel; Ashrafzadeh‐Kian, Susan; Bornhorst, Joshua A; Algeciras‐Schimnich, Alicia

Interrogating DNA methylation associated with Lewy body pathology in a cross brain-region and multi-cohort study

在一项跨脑区和多队列研究中,探究与路易体病理相关的DNA甲基化

Harvey, Joshua; Imm, Jennifer; Kouhsar, Morteza; Smith, Adam R; Creese, Byron; Smith, Rebecca G; Wheildon, Gregory; Chouliaras, Leonidas; Shireby, Gemma; Jaunmuktane, Zane; De Pablo-Fernández, Eduardo; Warner, Thomas; Lett, Debbie; Gveric, Djordje; Brooks, Hannah; Attems, Johannes; Thomas, Alan; Dempster, Emma; Ballard, Clive; O'Brien, John T; Aarsland, Dag; Mill, Jonathan; Pihlstrøm, Lasse; Pishva, Ehsan; Lunnon, Katie

Histone Acetylation Differentially Modulates CTCF-CTCF Loops and Intra-TAD Interactions.

组蛋白乙酰化差异性地调节 CTCF-CTCF 环和 TAD 内相互作用

Smith Rebecca G, Fu Yu, Schiela Kathleen L, Dautle Madison, Williams Ryan, Wilson Hannah M, Azadegan Chloe, Whetstine Johnathan R, Dekker Job, Liu Yu

Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF-AD study

EMIF-AD 研究中与阿尔茨海默病脑脊液生物标志物相关的血液 DNA 甲基化组学特征

Smith, Rebecca G; Pishva, Ehsan; Kouhsar, Morteza; Imm, Jennifer; Dobricic, Valerija; Johannsen, Peter; Wittig, Michael; Franke, Andre; Vandenberghe, Rik; Schaeverbeke, Jolien; Freund-Levi, Yvonne; Frölich, Lutz; Scheltens, Philip; Teunissen, Charlotte E; Frisoni, Giovanni; Blin, Olivier; Richardson, Jill C; Bordet, Régis; Engelborghs, Sebastiaan; de Roeck, Ellen; Martinez-Lage, Pablo; Altuna, Miren; Tainta, Mikel; Lleó, Alberto; Sala, Isabel; Popp, Julius; Peyratout, Gwendoline; Winchester, Laura; Nevado-Holgado, Alejo; Verhey, Frans; Tsolaki, Magda; Andreasson, Ulf; Blennow, Kaj; Zetterberg, Henrik; Streffer, Johannes; Vos, Stephanie J B; Lovestone, Simon; Visser, Pieter Jelle; Bertram, Lars; Lunnon, Katie

A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex

一项针对阿尔茨海默病表观基因组关联研究的荟萃分析突显了皮层中新的差异甲基化位点

Smith, Rebecca G; Pishva, Ehsan; Shireby, Gemma; Smith, Adam R; Roubroeks, Janou A Y; Hannon, Eilis; Wheildon, Gregory; Mastroeni, Diego; Gasparoni, Gilles; Riemenschneider, Matthias; Giese, Armin; Sharp, Andrew J; Schalkwyk, Leonard; Haroutunian, Vahram; Viechtbauer, Wolfgang; van den Hove, Daniel L A; Weedon, Michael; Brokaw, Danielle; Francis, Paul T; Thomas, Alan J; Love, Seth; Morgan, Kevin; Walter, Jörn; Coleman, Paul D; Bennett, David A; De Jager, Philip L; Mill, Jonathan; Lunnon, Katie

The histone modification H3K4me3 is altered at the ANK1 locus in Alzheimer's disease brain

阿尔茨海默病脑组织中ANK1基因位点的组蛋白修饰H3K4me3发生改变。

Smith, Adam R; Smith, Rebecca G; Macdonald, Ruby; Marzi, Sarah J; Burrage, Joe; Troakes, Claire; Al-Sarraj, Safa; Mill, Jonathan; Lunnon, Katie

Altered DNA methylation profiles in blood from patients with sporadic Creutzfeldt-Jakob disease

散发性克雅氏病患者血液中 DNA 甲基化谱发生改变

Luke C Dabin, Fernando Guntoro, Tracy Campbell, Tony Bélicard, Adam R Smith, Rebecca G Smith, Rachel Raybould, Jonathan M Schott, Katie Lunnon, Peter Sarkies, John Collinge, Simon Mead, Emmanuelle Viré

An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene

一项针对阿尔茨海默病血液的全基因组关联研究揭示了HOXB6基因中显著的DNA高甲基化现象。

Roubroeks, Janou A Y; Smith, Adam R; Smith, Rebecca G; Pishva, Ehsan; Ibrahim, Zina; Sattlecker, Martina; Hannon, Eilis J; Kłoszewska, Iwona; Mecocci, Patrizia; Soininen, Hilkka; Tsolaki, Magda; Vellas, Bruno; Wahlund, Lars-Olof; Aarsland, Dag; Proitsi, Petroula; Hodges, Angela; Lovestone, Simon; Newhouse, Stephen J; Dobson, Richard J B; Mill, Jonathan; van den Hove, Daniël L A; Lunnon, Katie

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease

DNA甲基化和羟甲基化的平行分析突显了阿尔茨海默病中与神经病理学相关的表观遗传变异

Smith, Adam R; Smith, Rebecca G; Pishva, Ehsan; Hannon, Eilis; Roubroeks, Janou A Y; Burrage, Joe; Troakes, Claire; Al-Sarraj, Safa; Sloan, Carolyn; Mill, Jonathan; van den Hove, Daniel L; Lunnon, Katie