日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chaperone-assisted expression and purification of the AML-associated Src-family kinase Fgr in Escherichia coli

在大肠杆菌中利用分子伴侣辅助表达和纯化与急性髓系白血病相关的Src家族激酶Fgr

Gonzalez-Areizaga, Giancarlo; Smithgall, Thomas E

An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck

SH3结合变构调节剂可稳定AML相关Src家族激酶Hck的整体构象。

Selzer, Ari M; Gerlach, Gabriella; Gonzalez-Areizaga, Giancarlo; Wales, Thomas E; Cui, Stephanie Y; Iyer, Prema; Engen, John R; Camacho, Carlos; Ishima, Rieko; Smithgall, Thomas E

Constitutive activation of the Src-family kinases Fgr and Hck enhances the tumor burden of acute myeloid leukemia cells in immunocompromised mice

Src 家族激酶 Fgr 和 Hck 的组成性激活可增加免疫功能低下小鼠中急性髓系白血病细胞的肿瘤负担

Sherry T Shu, Li Chen, Giancarlo Gonzalez-Areizaga, Thomas E Smithgall

Updating the genomic and clinicopathologic features of thoracic SMARCA4-deficient undifferentiated tumor: a mini-series including a long-term survivor

更新胸腔SMARCA4缺陷型未分化肿瘤的基因组和临床病理特征:包括一名长期生存者的系列研究

Ofori, Kenneth; Pagan, Carlos; Smithgall, Marie C; Jadalla, Asma Salah; Upadhyay Baskota, Swikrity; Crapanzano, John P; Hsiao, Susan; Mansukhani, Mahesh M

PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication.

PROTAC介导的HIV-1 Nef降解可有效恢复细胞表面CD4和MHC-I的表达,并阻断HIV-1的复制

Emert-Sedlak Lori A, Tice Colin M, Shi Haibin, Alvarado John J, Shu Sherry T, Reitz Allen B, Smithgall Thomas E

Cocrystallization of the Src-Family Kinase Hck with the ATP-Site Inhibitor A-419259 Stabilizes an Extended Activation Loop Conformation

Src 家族激酶 Hck 与 ATP 位点抑制剂 A-419259 共结晶可稳定延长的活化环构象

Ari M Selzer, John J Alvarado, Thomas E Smithgall

Nef defect attenuates HIV viremia and immune dysregulation in the bone marrow-liver-thymus-spleen (BLTS) humanized mouse model

Nef缺陷可减轻骨髓-肝脏-胸腺-脾脏(BLTS)人源化小鼠模型中的HIV病毒血症和免疫失调。

Shivkumar Biradar ,Yash Agarwal ,Antu Das ,Sherry T Shu ,Jasmine Samal ,Sara Ho ,Nickolas Kelly ,Deepika Mahesh ,Shreya Teredesai ,Isabella Castronova ,London Mussina ,Robbie B Mailliard ,Thomas E Smithgall ,Moses T Bility

Membrane-bound Merkel cell polyomavirus middle T protein constitutively activates PLCγ1 signaling through Src-family kinases.

膜结合的默克尔细胞多瘤病毒中T蛋白通过Src家族激酶组成性激活PLCγ1信号传导

Peng Wen-Yu, Abere Bizunesh, Shi Haibin, Toland Sabrina, Smithgall Thomas E, Moore Patrick S, Chang Yuan

Neutron Reflectometry and Molecular Simulations Demonstrate HIV-1 Nef Homodimer Formation on Model Lipid Bilayers

中子反射法和分子模拟证明 HIV-1 Nef 同型二聚体在模型脂质双层上形成

Frank Heinrich, Catherine E Thomas, John J Alvarado, Rebecca Eells, Alyssa Thomas, Mathieu Doucet, Kindra N Whitlatch, Manish Aryal, Mathias Lösche, Thomas E Smithgall

Use of pediatric thymus to humanize mice for HIV-1 mucosal transmission

使用儿童胸腺使小鼠人性化以进行 HIV-1 粘膜传播

Chandra N Roy, Sherry T Shu, Christopher Kline, Lora Rigatti, Thomas E Smithgall, Zandrea Ambrose