文献库，生知库 | 链接生命科学的每一步

日期影响因子

Gene Editing of a Carcinogenic Liver Fluke Tetraspanin Impairs Parasite Surface Biogenesis and Extracellular Vesicle Uptake by Human Host Cells

基因编辑致癌肝吸虫四跨膜蛋白会损害寄生虫表面生物合成和人类宿主细胞对细胞外囊泡的摄取

期刊:Journal of Infectious Diseases

影响因子:4.5

doi:10.1093/infdis/jiaf466

Chaiyadet, Sujittra; Ittiprasert, Wannaporn; Smout, Michael J; Khowawisetsut, Ladawan; Ruangsuwast, Apisit; Brindley, Paul J; Loukas, Alex; Laha, Thewarach

细胞生物学

发表日期：2026

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Immunomics-guided biomarker discovery for human liver fluke infection and infection-associated cholangiocarcinoma

免疫组学指导的人类肝吸虫感染和感染相关胆管癌生物标志物发现

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-61043-2

Sadaow, Lakkhana; Rodpai, Rutchanee; Smout, Michael J; Nakajima, Rie; Boonroumkaew, Patcharaporn; Sotillo, Javier; Tedla, Bemnet A; Luvira, Vor; Kitkhuandee, Amnat; Paonariang, Krisada; Sukeepaisarnjaroen, Wattana; Yamasaki, Hiroshi; Suttiprapa, Sutas; Laha, Thewarach; Sripa, Banchob; de Assis, Rafael; Jain, Aarti; Ittiprasert, Wannaporn; Mann, Victoria H; Wong, Yide; Felgner, Philip L; Maleewong, Wanchai; Brindley, Paul J; Loukas, Alex; Intapan, Pewpan M

免疫/内分泌

发表日期：2025

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Topological isomers of a potent wound healing peptide: Structural insights and implications for bioactivity

一种强效伤口愈合肽的拓扑异构体：结构解析及其对生物活性的影响

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2025.110340

Raffaelli, Tiziano; Wilson, David T; Mobli, Mehdi; Smout, Michael J; Zhao, Guangzu; Takjoo, Rozita; Bansal, Paramjit S; Yu, Rilei; Zhang, Zixuan; Loukas, Alex; Daly, Norelle L

发表日期：2025

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Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide-directed β-hairpin fold

对海星（Asterias rubens）肽的结构分析表明，其存在二硫键导向的β发夹折叠结构。

期刊:FEBS Open Bio

影响因子:2.3

doi:10.1002/2211-5463.13931

Takjoo, Rozita; Wilson, David T; Le Quilliec, Justine; Schmidt, Casey A; Zhao, Guangzu; Liddell, Michael J; Shaikh, Naeem Y; Sunagar, Kartik; Loukas, Alex; Smout, Michael J; Daly, Norelle L

发表日期：2025

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Development of an efficacious oral peptide vaccine against infection with the carcinogenic liver fluke Opisthorchis viverrini

开发一种针对致癌肝吸虫（Opisthorchis viverrini）感染的有效口服肽疫苗

doi:10.1016/j.vaccine.2025.127400

Phumrattanaprapin, Wuttipong; Shalash, Ahmed O; Skwarczynski, Mariusz; Smout, Michael J; Laha, Thewarach; Toth, Istvan; Loukas, Alex

发表日期：2025

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Mechanistic insights into liver-fluke-induced bile-duct cancer

肝吸虫诱发胆管癌的机制研究

期刊:Trends in Parasitology

影响因子:6.6

doi:10.1016/j.pt.2024.10.012

Smout, Michael J; Laha, Thewarach; Chaiyadet, Sujittra; Brindley, Paul J; Loukas, Alex

发表日期：2024

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Peptide derived from progranulin of the carcinogenic liver fluke, Opisthorchis viverrini stimulates cell hyperproliferation and proinflammatory cytokine production

源自致癌肝吸虫（Opisthorchis viverrini）前粒蛋白的肽可刺激细胞过度增殖和促炎细胞因子的产生。

doi:10.21203/rs.3.rs-2586058/v1

Hembasat, Thanapat; Chaiyadet, Sujittra; Ittiprasert, Wannaporn; Smout, Michael J; Young, Neil D; Loukas, Alex; Brindley, Paul J; Laha, Thewarach

免疫/内分泌

细胞生物学

发表日期：2023

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Tetraspanins from Opisthorchis viverrini stimulate cholangiocyte migration and inflammatory cytokine production

肝吸虫的四跨膜蛋白可刺激胆管细胞迁移和炎症细胞因子的产生。

doi:10.1101/2023.06.12.544604

Ruangsuwast, Apisit; Smout, Michael J; Brindley, Paul J; Loukas, Alex; Laha, Thewarach; Chaiyadet, Sujittra

细胞生物学

免疫/内分泌

发表日期：2023

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Tetraspanins from the liver fluke Opisthorchis viverrini stimulate cholangiocyte migration and inflammatory cytokine production

肝吸虫（Opisthorchis viverrini）的四跨膜蛋白可刺激胆管细胞迁移和炎症细胞因子生成。

doi:10.14411/fp.2023.017

Ruangsuwast, Apisit; Smout, Michael J; Brindley, Paul J; Loukas, Alex; Laha, Thewarach; Chaiyadet, Sujittra

细胞生物学

免疫/内分泌

发表日期：2023

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Natural-Product-Based Solutions for Tropical Infectious Diseases

热带传染病的天然产物解决方案

期刊:Clinical Microbiology Reviews

影响因子:19.3

doi:10.1128/CMR.00348-20

Adegboye, Oyelola; Field, Matt A; Kupz, Andreas; Pai, Saparna; Sharma, Dileep; Smout, Michael J; Wangchuk, Phurpa; Wong, Yide; Loiseau, Claire

发表日期：2021

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