The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms
mTORC2亚基RICTOR通过转录和表观遗传机制促进神经节苷脂生物合成,从而驱动乳腺癌进展。
期刊:PLoS Biology
影响因子:7.8
doi:10.1371/journal.pbio.3003362
Mohammad Nafees Ansari,Somesh K Jha,Ali Khan,Kajal Rajput,Nishant Pandey,Dolly Jain,Rajeshwari Tripathi,Nihal Medatwal,Pankaj Sharma,Sudeshna Datta,Animesh Kar,Trishna Pani,Sk Asif Ali,Kaushavi Cholke,Kajal Rana,Valiya P Snijesh,Geetashree Mukherjee,Suryanarayana V S Deo,Soumen Basak,Ashutosh Mishra,Jyothi S Prabhu,Arnab Mukhopadhyay,Avinash Bajaj,Ujjaini Dasgupta
乳腺癌
神经科学
表观遗传
肿瘤
MTOR
ORC2
Rictor
mTOR