日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Monoclonal humanized monovalent antibody blocking therapy for anti-NMDA receptor encephalitis.

用于治疗抗NMDA受体脑炎的单克隆人源化单价抗体阻断疗法

Kanno Atsuo, Kito Takuya, Maeda Masashi, Yamaki Shanni, Amano Yasushi, Shimomura Takuya, Anisimova Margarita, Kanazawa Naomi, Suzuki Koichiro, Razai Amir, Mihara Takuma, Kubo Kaori, Shimada Takeshi, Nakamura Koji, Nomura Naoko, Kondo Yuji, Okimoto Akira, Sugiyama Azusa, Park Deborah, Stein Ivar, Petshow Samuel, Vandendoren Valentin, Bilic Sanela, Kazimi Roghiye, Eastman Vallari, Snipas Scott J, Mitchell Mathew, Maurer Mari, Jefson Marty, Lichter Jay, Yamajuku Daisuke, Shirai Hiroki, Adachi Megumi, Hoeppner Daniel J, Kubo Satoshi, Zito Karen, Iizuka Takahiro, Flynn Peter, Matsumoto Mitsuyuki

Caspase-9 inhibition confers stronger neuronal and vascular protection compared to VEGF neutralization in a mouse model of retinal vein occlusion

在视网膜静脉阻塞小鼠模型中,与VEGF中和相比,Caspase-9抑制剂能提供更强的神经元和血管保护作用。

Avrutsky, Maria I; Chen, Claire W; Lawson, Jacqueline M; Snipas, Scott J; Salvesen, Guy S; Troy, Carol M

Gain of function of a metalloproteinase associated with multiple myeloma, bicuspid aortic valve, and Von Hippel-Lindau syndrome.

与多发性骨髓瘤、二叶式主动脉瓣和冯·希佩尔-林道综合征相关的金属蛋白酶的功能获得

Snipas Scott J, Jappelli Roberto, Torkamani Ali, Paternostro Giovanni, Salvesen Guy S

Quantification of Immunostained Caspase-9 in Retinal Tissue.

视网膜组织中免疫染色Caspase-9的定量分析

Colón Ortiz Crystal K, Potenski Anna M, Johnson Kendra V, Chen Claire W, Snipas Scott J, Jean Ying Y, Avrutsky Maria I, Troy Carol M

Engineering caspase 7 as an affinity reagent to capture proteolytic products

将 caspase 7 改造为亲和试剂以捕获蛋白水解产物

Razai, Amir S; Snipas, Scott J; Poreba, Marcin; Fasci, Domenico; Salvesen, Guy S

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design

抑制剂结合的SARS-CoV-2木瓜蛋白酶样蛋白酶的活性分析和晶体结构:抗COVID-19药物设计的框架

Rut, Wioletta; Lv, Zongyang; Zmudzinski, Mikolaj; Patchett, Stephanie; Nayak, Digant; Snipas, Scott J; El Oualid, Farid; Huang, Tony T; Bekes, Miklos; Drag, Marcin; Olsen, Shaun K

Counter Selection Substrate Library Strategy for Developing Specific Protease Substrates and Probes.

反向选择底物库策略用于开发特异性蛋白酶底物和探针

Poreba Marcin, Solberg Rigmor, Rut Wioletta, Lunde Ngoc Nguyen, Kasperkiewicz Paulina, Snipas Scott J, Mihelic Marko, Turk Dusan, Turk Boris, Salvesen Guy S, Drag Marcin

Expedient synthesis of highly potent antagonists of inhibitor of apoptosis proteins (IAPs) with unique selectivity for ML-IAP

高效合成对ML-IAP具有独特选择性的高效凋亡抑制蛋白(IAP)拮抗剂

Vamos, Mitchell; Welsh, Kate; Finlay, Darren; Lee, Pooi San; Mace, Peter D; Snipas, Scott J; Gonzalez, Monica L; Ganji, Santhi Reddy; Ardecky, Robert J; Riedl, Stefan J; Salvesen, Guy S; Vuori, Kristiina; Reed, John C; Cosford, Nicholas D P

Structural and kinetic determinants of protease substrates

蛋白酶底物的结构和动力学决定因素

Timmer, John C; Zhu, Wenhong; Pop, Cristina; Regan, Tim; Snipas, Scott J; Eroshkin, Alexey M; Riedl, Stefan J; Salvesen, Guy S

Activation-coupled membrane-type 1 matrix metalloproteinase membrane trafficking

激活偶联膜型1基质金属蛋白酶的膜转运

Wu, Yi I; Munshi, Hidayatullah G; Snipas, Scott J; Salvesen, Guy S; Fridman, Rafael; Stack, M Sharon