日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Clonal dynamics, tolerance, and adverse events after CD45-ADC-conditioned autologous HSPC transplantation in macaques

猕猴CD45-ADC预处理的自体造血干细胞移植后的克隆动力学、耐受性和不良事件

Hayal, Taha Bartu; Abraham, Diana M; Demirci, Selami; Fan, Xing; Zhou, Yifan; Hyzy, Sharon L; Lin, Michelle I; Linde, Nathaniel; Engels, Theresa; Golomb, Justin; Bonifacino, Aylin; Schifanella, Luca; Hoffmann, Victoria; Brinster, Lauren R; Blair, Robert V; Midkiff, Cecily C; Franchini, Genoveffa; Kaur, Amitinder; Tisdale, John F; Donahue, Robert E; Hong, So Gun; Wu, Chuanfeng; Dunbar, Cynthia E

cMPL-based purification and depletion of human hematopoietic stem cells: implications for pretransplant conditioning

基于cMPL的人类造血干细胞纯化和去除:对移植前预处理的意义

Araki, Daisuke; Hong, So Gun; Linde, Nathaniel; Fisk, Bryan; Redekar, Neelam; Salisbury-Ruf, Christi; Krouse, Allen; Engels, Theresa; Golomb, Justin; Dagur, Pradeep; Panicker, Sumith R; Kanthi, Yogendra; Magnani, Diogo M; Wang, Zhirui; Larochelle, Andre

In vivo tracking of ex-vivo-generated (89)Zr-oxine-labeled plasma cells by PET in a non-human primate model

利用PET在非人灵长类动物模型中对体外生成的(89)Zr-oxine标记的浆细胞进行体内追踪

Young, David J; Edwards, Abigail J; Quiroz Caceda, Kevin G; Liberzon, Ella; Barrientos, Johana; Hong, So Gun; Turner, Jacob; Choyke, Peter L; Arlauckas, Sean; Lazorchak, Adam S; Morgan, Richard A; Sato, Noriko; Dunbar, Cynthia E

Optimization of lentiviral delivery of barcoded anti-CD20 chimeric antigen receptors into rhesus macaque and human natural killer cells

优化利用慢病毒载体将带有条形码的抗CD20嵌合抗原受体递送至恒河猴和人类自然杀伤细胞

Hayal, Taha B; Mulla, Aman A; Allan, David S J; Duncan, Brynn B; Joshi, Saanika; Hong, So Gun; Basar, Rafet; Rezvani, Katayoun; Childs, Richard W; Wu, Chuanfeng; Dunbar, Cynthia E

Ongoing production of tissue-resident macrophages from hematopoietic stem cells in healthy adult macaques

健康成年猕猴体内造血干细胞持续产生组织驻留巨噬细胞

Rahmberg, Andrew R; Wu, Chuanfeng; Shin, Taehoon; Hong, So Gun; Pei, Luxin; Markowitz, Tovah E; Hickman, Heather D; Dunbar, Cynthia E; Brenchley, Jason M

Long-term tracking of haematopoietic clonal dynamics and mutations in non-human primate undergoing transplantation of lentivirally barcoded haematopoietic stem and progenitor cells

对接受慢病毒条形码造血干细胞和祖细胞移植的非人灵长类动物进行造血克隆动态和突变的长期追踪

Hosuru, Rohan V; Yang, Jack; Zhou, Yifan; Gin, Ashley; Hayal, Taha B; Hong, So Gun; Dunbar, Cynthia E; Wu, Chuanfeng

A RUNX1-FPDMM rhesus macaque model reproduces the human phenotype and predicts challenges to curative gene therapies

RUNX1-FPDMM 恒河猴模型重现了人类表型,并预测了治愈性基因疗法面临的挑战

Lee, Byung-Chul; Zhou, Yifan; Bresciani, Erica; Ozkaya, Neval; Dulau-Florea, Alina; Carrington, Blake; Shin, Tae-Hoon; Baena, Valentina; Syed, Zulfeqhar A; Hong, So Gun; Zhen, Tao; Calvo, Katherine R; Liu, Paul; Dunbar, Cynthia E

Fertility-preserving myeloablative conditioning using single-dose CD117 antibody-drug conjugate in a rhesus gene therapy model

在恒河猴基因治疗模型中使用单剂量 CD117 抗体-药物偶联物进行保留生育能力的骨髓抑制治疗

Naoya Uchida, Ulana Stasula, Selami Demirci, Paula Germino-Watnick, Malikiya Hinds, Anh Le, Rebecca Chu, Alexander Berg, Xiong Liu, Ling Su, Xiaolin Wu, Allen E Krouse, N Seth Linde, Aylin Bonifacino, So Gun Hong, Cynthia E Dunbar, Leanne Lanieri, Anjali Bhat, Rahul Palchaudhuri, Bindu Bennet, Megan

Investigation of the impact of clonal hematopoiesis on severity and pathophysiology of COVID-19 in rhesus macaques

研究克隆性造血对恒河猴 COVID-19 病情严重程度和病理生理的影响

Shin, Tae-Hoon; Zhou, Yifan; Lee, Byung-Chul; Hong, So Gun; Andrew, Shayne F; Flynn, Barbara J; Gagne, Matthew; Todd, John-Paul M; Moore, Ian N; Cook, Anthony; Lewis, Mark G; Foulds, Kathryn E; Seder, Robert A; Douek, Daniel C; Roederer, Mario; Dunbar, Cynthia E

A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions

猕猴克隆造血模型展示了TET2破坏克隆的扩增及其在测试干预措施方面的应用价值

Shin, Tae-Hoon; Zhou, Yifan; Chen, Shirley; Cordes, Stefan; Grice, Max Z; Fan, Xing; Lee, Byung-Chul; Aljanahi, Aisha A; Hong, So Gun; Vaughan, Kelli L; Mattison, Julie A; Kohama, Steven G; Fabre, Margarete A; Uchida, Naoya; Demirci, Selami; Corat, Marcus A F; Métais, Jean-Yves; Calvo, Katherine R; Buscarlet, Manuel; Natanson, Hannah; McGraw, Kathy L; List, Alan F; Busque, Lambert; Tisdale, John F; Vassiliou, George S; Yu, Kyung-Rok; Dunbar, Cynthia E