日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional analysis of R144 in the flavin oxidation mechanism of a flavin-dependent N-monooxygenase

黄素依赖性N-单加氧酶黄素氧化机制中R144的功能分析

Robinson, Reeder; Britt, Korliss; Sobrado, Pablo

The dynamics of the flavin, NADPH, and active site loops determine the mechanism of activation of class B flavin-dependent monooxygenases

黄素、NADPH 和活性位点环的动态变化决定了 B 类黄素依赖性单加氧酶的激活机制。

Pierdominici-Sottile, Gustavo; Palma, Juliana; Ferrelli, María Leticia; Sobrado, Pablo

Discovery of Two Inhibitors of the Type IV Pilus Assembly ATPase PilB as Potential Antivirulence Compounds.

发现两种 IV 型菌毛组装 ATPase PilB 抑制剂作为潜在的抗毒力化合物

Dye Keane J, Vogelaar Nancy J, O'Hara Megan, Sobrado Pablo, Santos Webster, Carlier Paul R, Yang Zhaomin

High-Throughput Screen for Inhibitors of the Type IV Pilus Assembly ATPase PilB.

高通量筛选 IV 型菌毛组装 ATPase PilB 抑制剂

Dye Keane J, Vogelaar Nancy J, Sobrado Pablo, Yang Zhaomin

Steric Control of the Rate-Limiting Step of UDP-Galactopyranose Mutase

UDP-半乳糖吡喃糖变位酶限速步骤的空间位阻控制

Pierdominici-Sottile, Gustavo; Cossio-Pérez, Rodrigo; Da Fonseca, Isabel; Kizjakina, Karina; Tanner, John J; Sobrado, Pablo

Multiple functionalities of reduced flavin in the non-redox reaction catalyzed by UDP-galactopyranose mutase

UDP-半乳糖吡喃糖变位酶催化的非氧化还原反应中还原型黄素的多种功能

Sobrado, Pablo; Tanner, John J

Identification of eukaryotic UDP-galactopyranose mutase inhibitors using the ThermoFAD assay.

利用 ThermoFAD 检测法鉴定真核生物 UDP-半乳糖吡喃糖变位酶抑制剂

Martín Del Campo Julia S, Eckshtain-Levi Meital, Sobrado Pablo

The Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase

抗生素失活酶——利福平单加氧酶的结构

Liu, Li-Kai; Abdelwahab, Heba; Martin Del Campo, Julia S; Mehra-Chaudhary, Ritcha; Sobrado, Pablo; Tanner, John J

An unprecedented NADPH domain conformation in lysine monooxygenase NbtG provides insights into uncoupling of oxygen consumption from substrate hydroxylation

赖氨酸单加氧酶NbtG中一种前所未有的NADPH结构域构象为氧消耗与底物羟基化解偶联提供了新的见解

Binda, Claudia; Robinson, Reeder M; Martin Del Campo, Julia S; Keul, Nicholas D; Rodriguez, Pedro J; Robinson, Howard H; Mattevi, Andrea; Sobrado, Pablo

Structure, mechanism, and dynamics of UDP-galactopyranose mutase

UDP-半乳糖吡喃糖变位酶的结构、机制和动力学

Tanner, John J; Boechi, Leonardo; Andrew McCammon, J; Sobrado, Pablo