Hyperglycemia in combination with excess fat intake promotes renal pyroptosis and fibrosis through Gα(12)-dependent endoplasmic reticulum stress.
高血糖与过量脂肪摄入相结合,通过 Gα(12) 依赖的内质网应激促进肾脏细胞焦亡和纤维化。
期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.124015
Khan Muhammad Sohaib, Kim Boram, Jeon Yerim, Tak Jihoon, Kim Yun Seok, Lee Sang Gil, Lee Eun Byul, Lee Chang-Hoon, Eom Cheol Bin, Lee Hyun Sook, Jang Hyeon-Ki, Lee Nakyeom, Kie Jeong Hae, Yang Jee Myung, Yang Yoon Mee, Kim Sang Geon