Epigenetic targeting of MECOM/KRAS axis by JIB-04 impairs tumorigenesis and cisplatin resistance in MECOM-amplified ovarian cancer.
JIB-04 通过表观遗传靶向 MECOM/KRAS 轴,抑制 MECOM 扩增型卵巢癌的肿瘤发生和顺铂耐药性
期刊:Cell Death Discovery
影响因子:7
doi:10.1038/s41420-025-02618-2
Singh Ibha, Karna Amarnath, Prajapati Anita, Solanki Ujjawal, Mukherjee Archana, Uppal Sheetal, Malhotra Pawan, Kumar Manoj, Agarwal Pallavi