日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Alternative pre-mRNA Splicing and Gene Expression Patterns in Midbrain Lineage Cells Carrying Familial Parkinson's Disease Mutations.

携带家族性帕金森病突变的中脑谱系细胞中可变前体mRNA剪接和基因表达模式

Lee Yeon J, Syed Khaja, Busquets Oriol, Li Hanqin, Dunnack Jesse, Bateup Helen S, Soldner Frank, Hockemeyer Dirk, Rio Donald C

Stem Cells, Genome Editing, and the Path to Translational Medicine

干细胞、基因组编辑与转化医学之路

Soldner, Frank; Jaenisch, Rudolf

S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models

PINK1的S-亚硝基化减弱了基于hiPSC的帕金森病模型中PINK1/Parkin依赖的线粒体自噬

Oh, Chang-Ki; Sultan, Abdullah; Platzer, Joseph; Dolatabadi, Nima; Soldner, Frank; McClatchy, Daniel B; Diedrich, Jolene K; Yates, John R 3rd; Ambasudhan, Rajesh; Nakamura, Tomohiro; Jaenisch, Rudolf; Lipton, Stuart A

Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression.

α-突触核蛋白远端增强子中的帕金森病相关风险变异体调节靶基因表达

Soldner Frank, Stelzer Yonatan, Shivalila Chikdu S, Abraham Brian J, Latourelle Jeanne C, Barrasa M Inmaculada, Goldmann Johanna, Myers Richard H, Young Richard A, Jaenisch Rudolf

Tracing dynamic changes of DNA methylation at single-cell resolution

以单细胞分辨率追踪DNA甲基化的动态变化

Stelzer, Yonatan; Shivalila, Chikdu Shakti; Soldner, Frank; Markoulaki, Styliani; Jaenisch, Rudolf

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

构建患者特异性神经细胞用于脑部疾病的体外研究

Brennand, Kristen J; Marchetto, M Carol; Benvenisty, Nissim; Brüstle, Oliver; Ebert, Allison; Izpisua Belmonte, Juan Carlos; Kaykas, Ajamete; Lancaster, Madeline A; Livesey, Frederick J; McConnell, Michael J; McKay, Ronald D; Morrow, Eric M; Muotri, Alysson R; Panchision, David M; Rubin, Lee L; Sawa, Akira; Soldner, Frank; Song, Hongjun; Studer, Lorenz; Temple, Sally; Vaccarino, Flora M; Wu, Jun; Vanderhaeghen, Pierre; Gage, Fred H; Jaenisch, Rudolf

Toward eliminating HLA class I expression to generate universal cells from allogeneic donors

旨在消除HLA I类分子的表达,从而从同种异体供体中生成通用细胞

Torikai, Hiroki; Reik, Andreas; Soldner, Frank; Warren, Edus H; Yuen, Carrie; Zhou, Yuanyue; Crossland, Denise L; Huls, Helen; Littman, Nicholas; Zhang, Ziying; Tykodi, Scott S; Kebriaei, Partow; Lee, Dean A; Miller, Jeffrey C; Rebar, Edward J; Holmes, Michael C; Jaenisch, Rudolf; Champlin, Richard E; Gregory, Philip D; Cooper, Laurence J N

Transgene excision has no impact on in vivo integration of human iPS derived neural precursors

转基因切除对人诱导多能干细胞衍生的神经前体细胞的体内整合没有影响。

Major, Tamara; Menon, Jayanthi; Auyeung, Gordon; Soldner, Frank; Hockemeyer, Dirk; Jaenisch, Rudolf; Tabar, Viviane

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

人类胚胎干细胞和诱导多能干细胞的染色质结构和基因表达程序

Guenther, Matthew G; Frampton, Garrett M; Soldner, Frank; Hockemeyer, Dirk; Mitalipova, Maya; Jaenisch, Rudolf; Young, Richard A

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors.

帕金森病患者来源的诱导多能干细胞,不含病毒重编程因子

Soldner Frank, Hockemeyer Dirk, Beard Caroline, Gao Qing, Bell George W, Cook Elizabeth G, Hargus Gunnar, Blak Alexandra, Cooper Oliver, Mitalipova Maisam, Isacson Ole, Jaenisch Rudolf