日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Synthesis of 3-desoxycollinoketone B and its ability to reduce Alzheimer-associated misfolded proteins

3-脱氧柯林酮B的合成及其减少阿尔茨海默病相关错误折叠蛋白的能力

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69662-z
Heo, Seongrok; Cha, Minhae; Zhung, Wonho; Kim, JiMin; Keereewan, Sirisuk; Cho, Illhwan; Park, MinSeol; Seo, Wonbin; Shin, Heewon; Yoon, Soljee; Ye, Suhyun; Heo, Jae-Kyung; Hwang, Hayoung; Kim, Woo Youn; Kim, YoungSoo; Han, Sunkyu
阿尔茨海默症
发表日期：2026
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YIAD-0501 directly dissociates aggregates of full-length and N-terminal pyroglutamate-modified forms of Aβ.

YIAD-0501 直接解离全长和 N 端焦谷氨酸修饰形式的 Aβ 的聚集体。

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-026-01999-5
Shin Heewon, Lee Sunhee, Seo Wonbin, Yoon Seok Hyun, Cho Illhwan, Ye Suhyun, Park InWook, Yoon Soljee, Park MinSeol, Kim Sunghyun, Lee Songmin, Kim Hye Yun, Kim Ikyon, Kim YoungSoo
表观遗传
发表日期：2026
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Modulation of Amyloid and Tau Aggregation to Alleviate Cognitive Impairment in a Transgenic Mouse Model of Alzheimer's Disease.

通过调节淀粉样蛋白和 Tau 蛋白聚集来缓解阿尔茨海默病转基因小鼠模型的认知障碍

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00006
Park Sohui, Shin Jisu, Kim Kyeonghwan, Kim Darong, Lee Won Seok, Lee Jusuk, Cho Illhwan, Park In Wook, Yoon Soljee, Lee Songmin, Kim Hye Yun, Lee Ji Hoon, Hong Ki Bum, Kim YoungSoo
免疫/内分泌
Mouse
发表日期：2024
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Aryloxypropanolamine mitigates Alzheimer‐like phenotype by directly removing amyloid aggregates

芳氧基丙醇胺通过直接清除淀粉样蛋白聚集体来减轻阿尔茨海默病样表型。

期刊:Journal of Clinical Medicine
影响因子:2.9
doi:10.3390/jcm13082218
Wu, Hongmin; Sawada, Takumi; Goto, Takafumi; Yoneyama, Tatsuya; Sasano, Tetsuo; Asada, Ken; Yoon, Soljee; Lee, Hee Yang; Cho, Illhwan; Lee, Donghee; Shin, Jisu; Kim, Kyeonghwan; Kim, Jimin; Kim, Hye Yun; Kim, Ikyon; Kim, YoungSoo
阿尔茨海默症
发表日期：2024
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Solid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β(3-42) peptide

焦谷氨酸淀粉样β(3-42)肽的固相合成及病理学评价

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-26616-x
Cho, Illhwan; Lee, HeeYang; Lee, Donghee; Park, In Wook; Yoon, Soljee; Kim, Hye Yun; Kim, YoungSoo
发表日期：2023
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Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models

芳氧基丙醇胺靶向淀粉样蛋白聚集体并逆转阿尔茨海默病小鼠模型中的阿尔茨海默病样表型

期刊:Alzheimers Research & Therapy
影响因子:7.9
doi:10.1186/s13195-022-01112-6
Hee Yang Lee #, Soljee Yoon #, Jeong Hwa Lee #, Keunwan Park, Youngeun Jung, Illhwan Cho, Donghee Lee, Jisu Shin, Kyeonghwan Kim, Sunmi Kim, Jimin Kim, Koeun Kim, Seung Hoon Han, Seong Muk Kim, Hye Ju Kim, Hye Yun Kim, Ikyon Kim, Young Soo Kim
神经
阿尔茨海默症
ELISA
ICC
IHC
Mouse
发表日期：2022
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Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer's disease

奎纳克林直接解离阿尔茨海默病 5XFAD 转基因小鼠模型脑中的淀粉样斑块

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-021-91563-y
Sohui Park #, Hye Yun Kim #, Hyun-A Oh #, Jisu Shin, In Wook Park, Soljee Yoon, Dong Ho Woo, YoungSoo Kim
神经
阿尔茨海默症
ELISA
ICC
IHC
Mouse
发表日期：2021
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