日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Translational Pharmacokinetics of Icotrokinra, a Targeted Oral Peptide that Selectively Blocks Interleukin-23 Receptor and Inhibits Signaling

靶向口服肽类药物Icotrokinra的转化药代动力学研究,该药物可选择性阻断白细胞介素-23受体并抑制信号传导

Knight, Beverly; Tammara, Brinda; Modi, Nishit B; Dallas, Shannon; Mardirosian, Saro; Wang, Jianyao; Laenen, Aline; Leclercq, Laurent; DiLoreto, Karen; Adriaenssen, Lieve; Moss, Darren; Polidori, David; Chaudhuri, Siladitya Ray; Park, Seonghee; Sensenhauser, Carlo; Ndifor, Anthony; Sukumaran, Siddharth; Baguet, Tristan; Shi, Yifan; Patel, Shefali; Geist, Brian; Fourie, Anne; Patch, Raymond; Sun, Chengzao; Barros, Stephanie A; Somani, Sandeep; Monshouwer, Mario

Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing

人类NAIP/NLRC4炎症小体组装和病原体感知的结构基础

Matico, Rosalie E; Yu, Xiaodi; Miller, Robyn; Somani, Sandeep; Ricketts, M Daniel; Kumar, Nikit; Steele, Ruth A; Medley, Quintus; Berger, Scott; Faustin, Benjamin; Sharma, Sujata

Modeling Chromatography Binding through Molecular Dynamics Simulations with Resin Fragments

利用分子动力学模拟和树脂片段对色谱结合进行建模

Stanevich, Vitali; Oyeniran, Oluyemi; Somani, Sandeep

Toward Biotherapeutics Formulation Composition Engineering using Site-Identification by Ligand Competitive Saturation (SILCS)

利用配体竞争饱和位点识别(SILCS)进行生物治疗制剂组成工程

Somani, Sandeep; Jo, Sunhwan; Thirumangalathu, Renuka; Rodrigues, Danika; Tanenbaum, Laura M; Amin, Ketan; MacKerell, Alexander D Jr; Thakkar, Santosh V

Computational Characterization of Antibody-Excipient Interactions for Rational Excipient Selection Using the Site Identification by Ligand Competitive Saturation-Biologics Approach

利用配体竞争饱和法进行位点识别的生物制剂方法,对抗体-辅料相互作用进行计算表征,以实现辅料的合理选择

Jo, Sunhwan; Xu, Amy; Curtis, Joseph E; Somani, Sandeep; MacKerell, Alexander D Jr

Homology-based hydrogen bond information improves crystallographic structures in the PDB

基于同源性的氢键信息可以改进PDB中的晶体结构。

van Beusekom, Bart; Touw, Wouter G; Tatineni, Mahidhar; Somani, Sandeep; Rajagopal, Gunaretnam; Luo, Jinquan; Gilliland, Gary L; Perrakis, Anastassis; Joosten, Robbie P

Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.

人类 IgG1 和 IgG4 Fc 变体的功能、生物物理和结构表征及其免疫功能的丧失

Tam Susan H, McCarthy Stephen G, Armstrong Anthony A, Somani Sandeep, Wu Sheng-Jiun, Liu Xuesong, Gervais Alexis, Ernst Robin, Saro Dorina, Decker Rose, Luo Jinquan, Gilliland Gary L, Chiu Mark L, Scallon Bernard J

Equilibrium molecular thermodynamics from Kirkwood sampling

柯克伍德采样法得到的平衡分子热力学

Somani, Sandeep; Okamoto, Yuko; Ballard, Andrew J; Wales, David J

Configurational entropy in protein-peptide binding: computational study of Tsg101 ubiquitin E2 variant domain with an HIV-derived PTAP nonapeptide

蛋白质-肽结合中的构象熵:Tsg101泛素E2变体结构域与HIV衍生PTAP九肽的计算研究

Killian, Benjamin J; Kravitz, Joslyn Yudenfreund; Somani, Sandeep; Dasgupta, Paramita; Pang, Yuan-Ping; Gilson, Michael K