日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deletion of RSK2 kinase alleviates age-dependent hypertension

RSK2激酶的缺失可缓解年龄相关性高血压

Ayon, Ramon; Wang, Yves T; Kalra, Jaspreet; Jin, Li; Chen, Yen-Lin; Polanowska-Grabowska, Renata; Sonkusare, Swapnil K; Christie, Christine K; Small, Eric M; Le, Thu H; Somlyo, Avril V

Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress.

Pannexin-3 以不依赖通道的方式稳定转录因子 Bcl6,从而防止血管氧化应激

Wolpe Abigail G, Luse Melissa A, Baryiames Christopher, Schug Wyatt J, Wolpe Jacob B, Johnstone Scott R, Dunaway Luke S, Juśkiewicz Zuzanna J, Loeb Skylar A, Askew Page Henry R, Chen Yen-Lin, Sabapathy Vikram, Pavelec Caitlin M, Wakefield Brent, Cifuentes-Pagano Eugenia, Artamonov Mykhaylo V, Somlyo Avril V, Straub Adam C, Sharma Rahul, Beier Frank, Barrett Eugene J, Leitinger Norbert, Pagano Patrick J, Sonkusare Swapnil K, Redemann Stefanie, Columbus Linda, Penuela Silvia, Isakson Brant E

Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS

解析RHOGAP家族蛋白的分子和功能基础:选择性灭活RHO家族蛋白的系统方法

Amin, Ehsan; Jaiswal, Mamta; Derewenda, Urszula; Reis, Katarina; Nouri, Kazem; Koessmeier, Katja T; Aspenström, Pontus; Somlyo, Avril V; Dvorsky, Radovan; Ahmadian, Mohammad R

Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction

血管收缩过程中,肌内皮连接处的血红蛋白α/eNOS偶联是清除一氧化氮所必需的。

Straub, Adam C; Butcher, Joshua T; Billaud, Marie; Mutchler, Stephanie M; Artamonov, Mykhaylo V; Nguyen, Anh T; Johnson, Tyler; Best, Angela K; Miller, Megan P; Palmer, Lisa A; Columbus, Linda; Somlyo, Avril V; Le, Thu H; Isakson, Brant E

Rho-kinase: regulation, (dys)function, and inhibition

Rho激酶:调控、功能(失调)和抑制

Amin, Ehsan; Dubey, Badri Nath; Zhang, Si-Cai; Gremer, Lothar; Dvorsky, Radovan; Moll, Jens M; Taha, Mohamed S; Nagel-Steger, Luitgard; Piekorz, Roland P; Somlyo, Avril V; Ahmadian, Mohammad R

Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 Å resolution

槲皮苷被鉴定为p90 S6核糖体激酶(RSK)抑制剂:其与RSK2 N端结构域复合物的1.8 Å分辨率结构

Derewenda, Urszula; Artamonov, Mykhaylo; Szukalska, Gabriela; Utepbergenov, Darkhan; Olekhnovich, Natalya; Parikh, Hardik I; Kellogg, Glen E; Somlyo, Avril V; Derewenda, Zygmunt S

Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury

细胞外基质的力学特性会改变平滑肌蛋白LPP及其伴侣蛋白palladin的表达;这与早期动脉粥样硬化和血管损伤有关。

Jin, Li; Hastings, Nicole E; Blackman, Brett R; Somlyo, Avril V

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF

关于RhoA特异性核苷酸交换因子PDZRhoGEF的自身抑制机制

Zheng, Meiying; Cierpicki, Tomasz; Momotani, Ko; Artamonov, Mykhaylo V; Derewenda, Urszula; Bushweller, John H; Somlyo, Avril V; Derewenda, Zygmunt S

Cep57, a multidomain protein with unique microtubule and centrosomal localization domains

Cep57是一种具有独特微管和中心体定位结构域的多结构域蛋白。

Momotani, Ko; Khromov, Alexander S; Miyake, Tsuyoshi; Stukenberg, P Todd; Somlyo, Avril V