日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic signatures in the highly virulent subtype B human immunodeficiency virus-1 conferring resistance to broadly neutralizing antibodies.

高致病性亚型 B 人类免疫缺陷病毒-1 中的遗传特征赋予其对广谱中和抗体的抵抗力

Honnayakanahalli Marichannegowda Manukumar, Agyekum Georgina, Aparicio Cinthya Zelaya, Heredia Alonso, Wang Yin, Song Hongshuo

Distinct memory CD4(+) T cell subset tropism of two CCR5-tropic HIV-1 in a rapid progressor

快速进展型患者体内两种CCR5嗜性HIV-1病毒具有不同的记忆性CD4(+) T细胞亚群嗜性

Marichannegowda, Manukumar Honnayakanahalli; Farah, Yasmine; Bose, Meera; Sanders-Buell, Eric; King, David; Francisco, Leilani; Eller, Leigh Anne; Rashid, Abdur; Tovanabutra, Sodsai; Michael, Nelson L; Robb, Merlin L; Song, Hongshuo

Transmission of highly virulent CXCR4 tropic HIV-1 through the mucosal route in an individual with a wild-type CCR5 genotype

在具有野生型CCR5基因型的个体中,通过黏膜途径传播高致病性CXCR4嗜性HIV-1

Marichannegowda, Manukumar Honnayakanahalli; Setua, Saini; Bose, Meera; Sanders-Buell, Eric; King, David; Zemil, Michelle; Wieczorek, Lindsay; Diaz-Mendez, Felisa; Chomont, Nicolas; Thomas, Rasmi; Francisco, Leilani; Eller, Leigh Anne; Polonis, Victoria R; Tovanabutra, Sodsai; Heredia, Alonso; Tagaya, Yutaka; Michael, Nelson L; Robb, Merlin L; Song, Hongshuo

IFNα induces CCR5 in CD4(+) T cells of HIV patients causing pathogenic elevation

IFNα诱导HIV患者CD4(+) T细胞中CCR5的表达,导致致病性升高。

Le Buanec, Hélène; Schiavon, Valérie; Merandet, Marine; How-Kit, Alexandre; Song, Hongshuo; Bergerat, David; Fombellida-Lopez, Céline; Bensussan, Armand; Bouaziz, Jean-David; Burny, Arsène; Darcis, Gilles; Sajadi, Mohammad M; Kottilil, Shyamasundaran; Zagury, Daniel; Gallo, Robert C

Tracking coreceptor switch of the transmitted/founder HIV-1 identifies co-evolution of HIV-1 antigenicity, coreceptor usage and CD4 subset targeting: the RV217 acute infection cohort study

追踪传播/创始HIV-1的辅助受体转换,揭示HIV-1抗原性、辅助受体使用和CD4亚群靶向性的共同进化:RV217急性感染队列研究

Marichannegowda, Manukumar Honnayakanahalli; Zemil, Michelle; Wieczorek, Lindsay; Sanders-Buell, Eric; Bose, Meera; O'Sullivan, Anne Marie; King, David; Francisco, Leilani; Diaz-Mendez, Felisa; Setua, Saini; Chomont, Nicolas; Phanuphak, Nittaya; Ananworanich, Jintanat; Hsu, Denise; Vasan, Sandhya; Michael, Nelson L; Eller, Leigh Anne; Tovanabutra, Sodsai; Tagaya, Yutaka; Robb, Merlin L; Polonis, Victoria R; Song, Hongshuo

Early Elevated IFNα Identified as the Key Mediator of HIV Pathogenesis and its low level a Hallmark of Elite Controllers

早期升高的IFNα被认为是HIV发病机制的关键介质,而其低水平是精英控制者的标志。

Le Buanec, Hélène; Schiavon, Valérie; Merandet, Marine; How-Kit, Alexandre; Bergerat, David; Fombellida-Lopez, Céline; Bensussan, Armand; Bouaziz, Jean-David; Burny, Arsène; Darcis, Gilles; Song, Hongshuo; Sajadi, Mohammad M; Kottilil, Shyamasundaran; Gallo, Robert C; Zagury, Daniel

Dynamics of Human Immunodeficiency Virus-1 Genetic Diversification During Acute Infection

急性感染期间人类免疫缺陷病毒-1基因多样化的动态变化

Song, Hongshuo; Bose, Meera; Pinyakorn, Suteeraporn; Sanders-Buell, Eric; O'Sullivan, Anne Marie; Silas, Daniel; Trichavaroj, Rapee; Nuntapinit, Bessara; Pham, Phuc T; Akapirat, Siriwat; Kroon, Eugène; de Souza, Mark; Gramzinski, Robert; Michael, Nelson L; Robb, Merlin L; Vasan, Sandhya; Tovanabutra, Sodsai; Ananworanich, Jintanat

Deep Sequencing Reveals Central Nervous System Compartmentalization in Multiple Transmitted/Founder Virus Acute HIV-1 Infection

深度测序揭示了多种传播/创始病毒急性 HIV-1 感染中枢神经系统的区室化

Tovanabutra, Sodsai; Sirijatuphat, Rujipas; Pham, Phuc T; Bonar, Lydia; Harbolick, Elizabeth A; Bose, Meera; Song, Hongshuo; Chang, David; Oropeza, Celina; O'Sullivan, Anne Marie; Balinang, Joyce; Kroon, Eugene; Colby, Donn J; Sacdalan, Carlo; Hellmuth, Joanna; Chan, Phillip; Prueksakaew, Peeriya; Pinyakorn, Suteeraporn; Jagodzinski, Linda L; Sutthichom, Duanghathai; Pattamaswin, Suwanna; de Souza, Mark; Gramzinski, Robert A; Kim, Jerome H; Michael, Nelson L; Robb, Merlin L; Phanuphak, Nittaya; Ananworanich, Jintanat; Valcour, Victor; Kijak, Gustavo H; Sanders-Buell, Eric; Spudich, Serena

Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences

多种 HIV-1 C 亚型传播/创始病毒向同一受感染者传播并非由轻微的表型差异决定。

Song, Hongshuo; Hora, Bhavna; Giorgi, Elena E; Kumar, Amit; Cai, Fangping; Bhattacharya, Tanmoy; Perelson, Alan S; Gao, Feng

Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation

预先存在的补偿性氨基酸会降低 HIV-1 T 细胞逃逸突变的适应性代价

Liu, Donglai; Zuo, Tao; Hora, Bhavna; Song, Hongshuo; Kong, Wei; Yu, Xianghui; Goonetilleke, Nilu; Bhattacharya, Tanmoy; Perelson, Alan S; Haynes, Barton F; McMichael, Andrew J; Gao, Feng