Song Zhenyuan相关文献与解析，生知库 | 链接生命科学的每一步

Hu Ruoci, Park Jooman, Qian Yanyu, Xiong Shaolei, Elsabbagh Ahmad Hamza, Chhikara Aditya, Fan Huailing, Shi Zuoxiao, Liu Lifeng, Li Yanhui, Song Zhenyuan, Mahmoud Abeer M, Chen Jiwang, Baur Joseph A, He Yanlin, Layden Brian T, Zhou Zhenqi, Xu Pingwen, Ong Sang-Ging, Wang Zilai, Jiang Yuwei

IL-3

IL-33

信号转导

Hepatic NMNAT1 is required to defend against alcohol-associated fatty liver disease.

肝脏NMNAT1是抵御酒精相关性脂肪肝疾病所必需的

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.adt6195

Ding Qinchao, Cao Feiwei, Zhuge Hui, Lai Shanglei, Cao Wenjing, Wei Haibin, Guo Rui, Qiu Jiannan, Song Qing, Pei Liuhua, Li Chaolan, Si Caijuan, Sun Zhaoli, Song Zhenyuan, Dou Xiaobing, Li Songtao

Increasing cellular NAD(+) protects hepatocytes against palmitate-induced lipotoxicity by preventing PARP-1 inhibition and the mTORC1-p300 pathway activation.

增加细胞内 NAD(+) 可防止 PARP-1 抑制和 mTORC1-p300 通路激活，从而保护肝细胞免受棕榈酸酯诱导的脂毒性

期刊:American Journal of Physiology-Cell Physiology

影响因子:4.7

doi:10.1152/ajpcell.00946.2024

Guo Rui, Li Yanhui, Song Qing, Huang Rong, Ge Xiaodong, Nieto Natalia, Jiang Yuwei, Song Zhenyuan

Saturated phosphatidic acids induce mTORC1-driven integrated stress response contributing to glucolipotoxicity in hepatocytes.

饱和磷脂酸诱导 mTORC1 驱动的整合应激反应，导致肝细胞糖脂毒性

期刊:American Journal of Physiology-Gastrointestinal and Liver Physiology

影响因子:3.3

doi:10.1152/ajpgi.00027.2025

Guo Rui, Li Yanhui, Jiang Yuwei, Khan Md Wasim, Layden Brian T, Song Zhenyuan

Estrogen counteracts age-related decline in beige adipogenesis through the NAMPT-regulated ER stress response

雌激素通过NAMPT调节的内质网应激反应来对抗与年龄相关的米色脂肪细胞生成减少。

期刊:Nature Aging

影响因子:17

doi:10.1038/s43587-024-00633-z.

Jooman Park #,Ruoci Hu #,Yanyu Qian,Shaolei Xiong,Asma Sana El-Sabbagh,Meram Ibrahim,Jaden Wang,Ziqiao Xu,Zhengjia Chen,Qing Song,Zhenyuan Song,Gege Yan,Abeer M Mahmoud,Yanlin He,Brian T Layden,Jiwang Chen,Sang-Ging Ong,Pingwen Xu,Yuwei Jiang

Personalized neoantigen vaccines as early intervention in untreated patients with lymphoplasmacytic lymphoma: a non-randomized phase 1 trial

针对未经治疗的淋巴浆细胞淋巴瘤患者，采用个性化新抗原疫苗进行早期干预：一项非随机 I 期试验

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-50880-2

Szymon J Szymura ，Lin Wang ，Tiantian Zhang ，Soung-Chul Cha ，Joo Song ，Zhenyuan Dong ，Aaron Anderson ，Elizabeth Oh ，Vincent Lee ，Zhe Wang ，Sapna Parshottam ，Sheetal Rao ，Jasper B Olsem ，Brandon N Crumpton ，Hans C Lee ，Elisabet E Manasanch ，Sattva Neelapu ，Larry W Kwak ，Sheeba K Thomas

Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation

肠道来源的氨通过促进乙醇代谢和激活ATF4依赖的从头脂肪生成，促进酒精相关性脂肪肝的发生发展。

期刊:Metabolism-Clinical and Experimental

影响因子:11.9

doi:10.1016/j.metabol.2023.155740

Song, Qing; Hwang, Chueh-Lung; Li, Yanhui; Wang, Jun; Park, Jooman; Lee, Samuel M; Sun, Zhaoli; Sun, Jun; Xia, Yinglin; Nieto, Natalia; Cordoba-Chacon, Jose; Jiang, Yuwei; Dou, Xiaobing; Song, Zhenyuan

The Notch-PDGFRβ axis suppresses brown adipocyte progenitor differentiation in early post-natal mice

Notch-PDGFRβ轴抑制出生早期小鼠棕色脂肪细胞祖细胞的分化

期刊:Developmental Cell

影响因子:10.7

doi:10.1016/j.devcel.2024.03.012

Zuoxiao Shi ，Shaolei Xiong ，Ruoci Hu ，Zilai Wang ，Jooman Park ，Yanyu Qian ，Jaden Wang ，Pratibha Bhalla ，Nipun Velupally ，Qing Song ，Zhenyuan Song ，Minsun Stacey Jeon ，Ke Kurt Zhang ，Linlin Xie ，Brian T Layden ，Sang-Ging Ong ，Yuwei Jiang

Protopanaxadiol prevents cisplatin-induced acute kidney injury by regulating ferroptosis

原人参二醇通过调节铁死亡预防顺铂诱导的急性肾损伤

期刊:Journal of Pharmacy and Pharmacology

影响因子:2.8

doi:10.1093/jpp/rgae050

Zeyu Song, Zhenyuan Li, Tao Pan, Teng Liu, Baifang Gong, Zhixia Wang, Ke Liu, Huaying Fan

Genetically prolonged beige fat in male mice confers long-lasting metabolic health

遗传延长的雄性小鼠米色脂肪可带来持久的代谢健康

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-38471-z

Ruifan Wu #, Jooman Park #, Yanyu Qian, Zuoxiao Shi, Ruoci Hu, Yexian Yuan, Shaolei Xiong, Zilai Wang, Gege Yan, Sang-Ging Ong, Qing Song, Zhenyuan Song, Abeer M Mahmoud, Pingwen Xu, Congcong He, Robert W Arpke, Michael Kyba, Gang Shu, Qingyan Jiang, Yuwei Jiang3

代谢

发表日期：2023

文献求助收藏

ERÎ± activates NAMPT/IL-33 signaling to enhance beige thermogenesis and metabolic fitness.

ERÎ±激活NAMPT/IL-33信号通路，增强米色细菌产热和代谢适应性。

Hepatic NMNAT1 is required to defend against alcohol-associated fatty liver disease.

肝脏NMNAT1是抵御酒精相关性脂肪肝疾病所必需的

Increasing cellular NAD(+) protects hepatocytes against palmitate-induced lipotoxicity by preventing PARP-1 inhibition and the mTORC1-p300 pathway activation.

增加细胞内 NAD(+) 可防止 PARP-1 抑制和 mTORC1-p300 通路激活，从而保护肝细胞免受棕榈酸酯诱导的脂毒性

Saturated phosphatidic acids induce mTORC1-driven integrated stress response contributing to glucolipotoxicity in hepatocytes.

饱和磷脂酸诱导 mTORC1 驱动的整合应激反应，导致肝细胞糖脂毒性

Estrogen counteracts age-related decline in beige adipogenesis through the NAMPT-regulated ER stress response

雌激素通过NAMPT调节的内质网应激反应来对抗与年龄相关的米色脂肪细胞生成减少。

Personalized neoantigen vaccines as early intervention in untreated patients with lymphoplasmacytic lymphoma: a non-randomized phase 1 trial

针对未经治疗的淋巴浆细胞淋巴瘤患者，采用个性化新抗原疫苗进行早期干预：一项非随机 I 期试验

Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation

肠道来源的氨通过促进乙醇代谢和激活ATF4依赖的从头脂肪生成，促进酒精相关性脂肪肝的发生发展。

The Notch-PDGFRβ axis suppresses brown adipocyte progenitor differentiation in early post-natal mice

Notch-PDGFRβ轴抑制出生早期小鼠棕色脂肪细胞祖细胞的分化

Protopanaxadiol prevents cisplatin-induced acute kidney injury by regulating ferroptosis

原人参二醇通过调节铁死亡预防顺铂诱导的急性肾损伤

Genetically prolonged beige fat in male mice confers long-lasting metabolic health

遗传延长的雄性小鼠米色脂肪可带来持久的代谢健康