日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Multispecies, Modality-Agnostic Scalable In Vivo Mosaic Screening Platform for Therapeutic Target Discovery

用于治疗靶点发现的多物种、与成像方式无关的可扩展体内嵌合筛选平台

Sontake, Vishwaraj; Kartha, Vinay; Sahu, Neety; Fuentes, Daniel R; Chio, Linda; Miyazaki, Hikaru; Chen, Jingshu; Gupta, Arnav; Nonora, Jesi; Vaidyanathan, Arthi; Shambhu, Smitha; Donepudi, Gayathri; Le, Carmen; Fung, Lianna; Lim, Amber; Bowman, Chase; Garcia, Diego; Popov, Dimitry; Fagan, Kelly; Longtine, Charlie; Sampedro, Juana M Cruz; Hayward, Samuel B; Biedrzycki, Adam; Powell, Barclay B; Doroschak, Katie; Levings, Rachael Watson; Carrico, Chris; Driver, Ian; Towne, Chris; LePort, Francisco; Jensen, Martin Borch

Wilms tumor 1 impairs apoptotic clearance of fibroblasts in distal fibrotic lung lesions

Wilms肿瘤1会损害远端纤维化肺病灶中成纤维细胞的凋亡清除。

Ediga, Harshavardhana H; Vemulapalli, Chanukya P; Sontake, Vishwaraj; Patel, Pradeep K; Miyazaki, Hikaru; Popov, Dimitry; Jensen, Martin B; Jegga, Anil G; Huang, Steven K; Englert, Christoph; Schedl, Andreas; Gupta, Nishant; McCormack, Francis X; Madala, Satish K

Ferret model of bleomycin-induced lung injury shares features of human idiopathic pulmonary fibrosis.

雪貂博来霉素诱导肺损伤模型与人类特发性肺纤维化具有相似特征。

Wu Shuang, Driver Ian, Luo Meihui, Miyazaki Hikaru, Shambhu Smitha, Popov Dimitry, Yang Liyuan, Wang Jing, Ma Jia, Guo Junfeng, Atha Jarron, Tata Aleksandra, Hoffman Eric A, Wang Yujiong, Tata Purushothama Rao, Jensen Martin B, Engelhardt John F, Sontake Vishwaraj, Liu Xiaoming

Ferret model of bleomycin-induced lung injury shares features of human idiopathic pulmonary fibrosis.

雪貂博来霉素诱导肺损伤模型与人类特发性肺纤维化具有相似特征

Wu Shuang, Drive Ian, Luo Meihui, Miyazaki Hikaru, Shambhu Smitha, Popov Dimitry, Yang Liyuan, Wang Jing, Ma Jia, Guo Junfeng, Atha Jarron, Tata Aleksandra, Hoffman Eric A, Wang Yujiong, Tata Purushothama Rao, Jensen Martin B, Engelhardt John F, Sontake Vishwaraj, Liu Xiaoming

SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia.

SARS-CoV-2 变异株在原代人呼吸道上皮细胞中的适应性和适应性值得关注

Meganck Rita M, Edwards Caitlin E, Mallory Michael L, Lee Rhianna E, Dang Hong, Bailey Alexis B, Wykoff Jason A, Gallant Samuel C, Zhu Deanna R, Yount Boyd L, Kato Takafumi, Shaffer Kendall M, Nakano Satoko, Cawley Anne Marie, Sontake Vishwaraj, Wang Jeremy R, Hagan Robert S, Miller Melissa B, Tata Purushothama Rao, Randell Scott H, Tse Longping V, Ehre Camille, Okuda Kenichi, Boucher Richard C, Baric Ralph S

Host range, transmissibility and antigenicity of a pangolin coronavirus

穿山甲冠状病毒的宿主范围、传播性和抗原性

Yixuan J Hou, Shiho Chiba, Sarah R Leist, Rita M Meganck, David R Martinez, Alexandra Schäfer, Nicholas J Catanzaro, Vishwaraj Sontake, Ande West, Catlin E Edwards, Boyd Yount, Rhianna E Lee, Samuel C Gallant, Seth J Zost, John Powers, Lily Adams, Edgar F Kong, Melissa Mattocks, Aleksandra Tata, Sco

Human distal lung maps and lineage hierarchies reveal a bipotent progenitor

人类远端肺图谱和谱系层级揭示了一种双潜能祖细胞

Preetish Kadur Lakshminarasimha Murthy # ,Vishwaraj Sontake # ,Aleksandra Tata ,Yoshihiko Kobayashi ,Lauren Macadlo ,Kenichi Okuda ,Ansley S Conchola ,Satoko Nakano ,Simon Gregory ,Lisa A Miller ,Jason R Spence ,John F Engelhardt ,Richard C Boucher ,Jason R Rock ,Scott H Randell ,Purushothama Rao Tata

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

SARS-CoV-2反向遗传学揭示呼吸道感染梯度存在差异

Yixuan J Hou ,Kenichi Okuda ,Caitlin E Edwards ,David R Martinez ,Takanori Asakura ,Kenneth H Dinnon 3rd ,Takafumi Kato ,Rhianna E Lee ,Boyd L Yount ,Teresa M Mascenik ,Gang Chen ,Kenneth N Olivier ,Andrew Ghio ,Longping V Tse ,Sarah R Leist ,Lisa E Gralinski ,Alexandra Schäfer ,Hong Dang ,Rodney Gilmore ,Satoko Nakano ,Ling Sun ,M Leslie Fulcher ,Alessandra Livraghi-Butrico ,Nathan I Nicely ,Mark Cameron ,Cheryl Cameron ,David J Kelvin ,Aravinda de Silva ,David M Margolis ,Alena Markmann ,Luther Bartelt ,Ross Zumwalt ,Fernando J Martinez ,Steven P Salvatore ,Alain Borczuk ,Purushothama R Tata ,Vishwaraj Sontake ,Adam Kimple ,Ilona Jaspers ,Wanda K O'Neal ,Scott H Randell ,Richard C Boucher ,Ralph S Baric

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction

基于人肺干细胞的肺泡球为了解SARS-CoV-2介导的干扰素反应和肺泡细胞功能障碍提供了新的视角

Hiroaki Katsura,Vishwaraj Sontake,Aleksandra Tata,Yoshihiko Kobayashi,Caitlin E Edwards,Brook E Heaton,Arvind Konkimalla,Takanori Asakura,Yu Mikami,Ethan J Fritch,Patty J Lee,Nicholas S Heaton,Richard C Boucher,Scott H Randell,Ralph S Baric,Purushothama Rao Tata

BALO: a "mini lung" model to study cell-cell interactions

BALO:一种用于研究细胞间相互作用的“迷你肺”模型

Sontake, Vishwaraj; Tata, Purushothama Rao