日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Small-molecule CBLB inhibitor abolishes EGFR ubiquitination, reduces receptor endocytosis, and diminishes cell motility signaling

小分子CBLB抑制剂可消除EGFR泛素化,减少受体内吞作用,并减弱细胞运动信号传导。

Pinilla-Macua, Itziar; Mukerji, Ratul; Cohen, Frederick; Sorkin, Alexander

Systems-level consequences of low RAF abundance for EGFR-ERK signaling

RAF 丰度低对 EGFR-ERK 信号通路系统层面的影响

Lee, Sung Hyun; Myers, Paul J; Mendrzycki, Max C; Brown, Kevin S; Loew, Leslie M; Sorkin, Alexander; Lazzara, Matthew J

Molecular determinants for the endocytosis of the voltage-gated K(+) channel Kv1.3

电压门控K(+)通道Kv1.3内吞作用的分子决定因素

Estadella, Irene; Navarro-Pérez, María; Colomer-Molera, Magalí; Dustin, Michael L; Sorkin, Alexander; Capera, Jesusa; Felipe, Antonio

The Chromosome 19 miRNA cluster guards trophoblasts against overacting innate immunity

19号染色体上的miRNA簇保护滋养层细胞免受过度活跃的先天免疫反应的影响

Mouillet, Jean-Francois; Ouyang, Yingshi; Sadovsky, Elena; Kothandan, Vinoth K; Sorenson, Heather L; Badeau, Logan J; Sarkar, Saumendra N; Chu, Tianjiao; Sorkin, Alexander; Sadovsky, Yoel

The Chromosome 19 miRNA Cluster Guards Trophoblasts Against Overacting Innate Immunity

19号染色体上的miRNA簇保护滋养层细胞免受过度活跃的先天免疫反应的影响

Mouillet, Jean-Francois; Ouyang, Yingshi; Sadovsky, Elena; Kothnadan, Vinoth K; Sorenson, Heather L; Badeau, Logan J; Sarkar, Saumendra N; Chu, Tianjiao; Sorkin, Alexander; Sadovsky, Yoel

Systems-level Consequences of Low RAF Abundance for EGFR-ERK Signaling

低 RAF 丰度对 EGFR-ERK 信号通路系统层面的影响

Lee, Sung Hyun; Myers, Paul J; Brown, Kevin S; Loew, Leslie M; Sorkin, Alexander; Lazzara, Matthew J

E3 ligase recruitment by UBQLN2 protects substrates from proteasomal degradation.

UBQLN2 募集 E3 连接酶可保护底物免受蛋白酶体降解。

Scheutzow Ashley N, Thanthirige Sachini, Siffer Gracie, Sorkin Alexander D, Wohlever Matthew L

Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters during collective cell migration of epithelial cells

表皮生长因子受体的低亲和力配体是上皮细胞集体迁移过程中的长程信号传递分子。

Deguchi, Eriko; Lin, Shuhao; Hirayama, Daiki; Matsuda, Kimiya; Tanave, Akira; Sumiyama, Kenta; Tsukiji, Shinya; Otani, Tetsuhisa; Furuse, Mikio; Sorkin, Alexander; Matsuda, Michiyuki; Terai, Kenta

Cbl and Cbl-b independently regulate EGFR through distinct receptor interaction modes

Cbl 和 Cbl-b 通过不同的受体相互作用模式独立调节 EGFR

Pinilla-Macua, Itziar; Sorkin, Alexander

Endocytic down-regulation of the striatal dopamine transporter by amphetamine in sensitized mice in sex-dependent manner

苯丙胺以性别依赖的方式通过内吞作用下调致敏小鼠纹状体多巴胺转运蛋白

Bagalkot, Tarique; Sorkin, Alexander