日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Results of the Phase I/II Study and Preliminary B-cell Gene Signature of Combined Inhibition of Glutamine Metabolism and EGFR in Colorectal Cancer

结直肠癌中谷氨酰胺代谢和 EGFR 联合抑制的 I/II 期研究结果及初步 B 细胞基因特征

Ciombor, Kristen K; Bae, Seong-Woo; Whisenant, Jennifer G; Ayers, Gregory D; Sheng, Quanhu; Peterson, Todd E; Smith, Gary T; Lin, Kangyu; Chowdhury, Saikat; Kanikarla Marie, Preeti; Sorokin, Alexey; Cohen, Allison S; Goff, Laura W; Cardin, Dana B; Shen, John Paul; Kopetz, Scott; Eng, Cathy; Shyr, Yu; Berlin, Jordan; Manning, H Charles

Adaptive Plasticity Tumor Cells Modulate MAPK-Targeting Therapy Response in Colorectal Cancer

适应性可塑性肿瘤细胞调节结直肠癌中 MAPK 靶向治疗的反应

Villarreal, Oscar E; Xu, Yixin; Tran, Ha; Machado, Annette; Prescod, Dionne; Anderson, Amanda; Minelli, Rosalba; Peoples, Mike; Martinez, Alejandro Hernandez; Lee, Hey Min; Wong, Chi Wut; Fowlkes, Natalie; Kanikarla, Preeti; Sorokin, Alexey; Alshenaifi, Jumanah; Coker, Olu; Lin, Kangyu; Bristow, Chris; Viale, Andrea; Shen, John Paul; Parseghian, Christine; Marszalek, Joseph R; Corcoran, Ryan; Kopetz, Scott

Reprogramming of Cellular Plasticity via ETS and MYC Core-regulatory Circuits During Response to MAPK Inhibition in BRAF-mutant Colorectal Cancer

在BRAF突变型结直肠癌中,MAPK抑制反应期间ETS和MYC核心调控回路介导的细胞可塑性重编程

Lee, Hey Min; Zheng, Zhao; Sorokin, Alexey; Wong, Chi Wut; Napolitano, Stefania; Chowdhury, Saikat; Kanikarla, Preeti Marie; Singh, Anand K; Kochat, Veena; Bristow, Christopher A; Srinivasan, Sanjana; Peoples, Michael; Arslan, Emre; Alshenaifi, Jumanah Yousef; Villarreal, Oscar E; Morris, Van K; Shen, John Paul; Meric-Bernstam, Funda; Jain, Abhinav K; Fowlkes, Natalie Wall; Anderson, Amanda; Menter, David G; Saw, Ajay Kumar; Rai, Kunal; Kopetz, Scott

Epigenome Reprogramming Through H3K27 and H3K4 Trimethylation as a Resistance Mechanism to DNA Methylation Inhibition in BRAFV600E-Mutated Colorectal Cancer.

BRAFV600E突变型结直肠癌中通过H3K27和H3K4三甲基化进行表观基因组重编程,作为DNA甲基化抑制的耐药机制

Lee Hey Min, Saw Ajay Kumar, Morris Van K, Napolitano Stefania, Bristow Christopher, Srinivasan Sanjana, Peoples Micheal, Sorokin Alexey, Kanikarla Marie Preeti, Schulz Jonathan, Singh Anand K, Terranova Christopher, Coker Oluwadara, Jain Abhinav, Kopetz Scott, Rai Kunal

Resistance Mechanisms to Anti-Epidermal Growth Factor Receptor Therapy in RAS/RAF Wild-Type Colorectal Cancer Vary by Regimen and Line of Therapy

RAS/RAF野生型结直肠癌对表皮生长因子受体抑制剂治疗的耐药机制因治疗方案和治疗线数而异

Parseghian, Christine M; Sun, Ryan; Woods, Melanie; Napolitano, Stefania; Lee, Hey Min; Alshenaifi, Jumanah; Willis, Jason; Nunez, Shakayla; Raghav, Kanwal P; Morris, Van K; Shen, John P; Eluri, Madhulika; Sorokin, Alexey; Kanikarla, Preeti; Vilar, Eduardo; Rehn, Marko; Ang, Agnes; Troiani, Teresa; Kopetz, Scott

Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer

染色质状态动态变化为结直肠癌增强子亚型的特定治疗策略提供了依据

Orouji, Elias; Raman, Ayush T; Singh, Anand K; Sorokin, Alexey; Arslan, Emre; Ghosh, Archit K; Schulz, Jonathan; Terranova, Christopher; Jiang, Shan; Tang, Ming; Maitituoheti, Mayinuer; Callahan, Scot C; Barrodia, Praveen; Tomczak, Katarzyna; Jiang, Yingda; Jiang, Zhiqin; Davis, Jennifer S; Ghosh, Sukhen; Lee, Hey Min; Reyes-Uribe, Laura; Chang, Kyle; Liu, Yusha; Chen, Huiqin; Azhdarinia, Ali; Morris, Jeffrey; Vilar, Eduardo; Carmon, Kendra S; Kopetz, Scott E; Rai, Kunal

Targeting RAS Mutant Colorectal Cancer with Dual Inhibition of MEK and CDK4/6

利用MEK和CDK4/6双重抑制靶向RAS突变型结直肠癌

Sorokin, Alexey V; Kanikarla Marie, Preeti; Bitner, Lea; Syed, Muddassir; Woods, Melanie; Manyam, Ganiraju; Kwong, Lawrence N; Johnson, Benny; Morris, Van K; Jones, Philip; Menter, David G; Lee, Michael S; Kopetz, Scott

Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406)

伊立替康和西妥昔单抗联合或不联合维莫非尼治疗BRAF突变转移性结直肠癌的随机试验(SWOG S1406)

Kopetz, Scott; Guthrie, Katherine A; Morris, Van K; Lenz, Heinz-Josef; Magliocco, Anthony M; Maru, Dipen; Yan, Yibing; Lanman, Richard; Manyam, Ganiraju; Hong, David S; Sorokin, Alexey; Atreya, Chloe E; Diaz, Luis A; Allegra, Carmen; Raghav, Kanwal P; Wang, Stephen E; Lieu, Christopher H; McDonough, Shannon L; Philip, Philip A; Hochster, Howard S

Clinical and Functional Characterization of Atypical KRAS/NRAS Mutations in Metastatic Colorectal Cancer

转移性结直肠癌中非典型KRAS/NRAS突变的临床和功能特征

Loree, Jonathan M; Wang, Yucai; Syed, Muddassir A; Sorokin, Alexey V; Coker, Oluwadara; Xiu, Joanne; Weinberg, Benjamin A; Vanderwalde, Ari M; Tesfaye, Anteneh; Raymond, Victoria M; Miron, Benjamin; Tarcic, Gabi; Zelichov, Ori; Broaddus, Russell R; Ng, Patrick Kwok Shing; Jeong, Kang Jin; Tsang, Yiu Huen; Mills, Gordon B; Overman, Michael J; Grothey, Axel; Marshall, John L; Kopetz, Scott

The Provocative Roles of Platelets in Liver Disease and Cancer

血小板在肝病和癌症中的重要作用

Kanikarla Marie, Preeti; Fowlkes, Natalie W; Afshar-Kharghan, Vahid; Martch, Stephanie L; Sorokin, Alexey; Shen, John Paul; Morris, Van K; Dasari, Arvind; You, Nancy; Sood, Anil K; Overman, Michael J; Kopetz, Scott; Menter, David George