日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Large variations in total and allele-specific transcript expression in a disease mutation-independent manner

总转录本表达和等位基因特异性转录本表达均存在与疾病突变无关的显著差异。

Freyberg, Moritz; Bewig, Merete; Bampi, Giovana Bavia; Manfredi, Candela; Joshi, Disha; Rauscher, Robert; Hong, Jeong S; Große-Onnebrink, Jörg; Sutharsan, Sivagurunathan; Stehling, Florian; Bobis, Ingrid; Ballmann, Manfred; Sorscher, Eric J; Ignatova, Zoya

Barriers to the Pharmacologic Rescue of W1282X CFTR

W1282X CFTR 药物治疗的障碍

Manfredi, Candela; Rab, Andras; Joshi, Disha; Winters, Ashlyn G; Jackson, JaNise J; Molina, Sam; Koval, Michael; Khazanov, Netaly; Jacobson, Madison; Oliver, Kathryn; Senderowitz, Hanoch; Sorscher, Eric J; Hong, Jeong S

Reconstitution of CFTR ubiquitination identifies lysine-420 as a regulator of cell surface residence and current

CFTR泛素化的重建表明赖氨酸-420是细胞表面驻留和电流的调节因子。

Goeckeler-Fried, Jennifer L; Zeng, Xuemei; Hong, Jeong S; Joshi, Disha; Yang, Zhengrong; Jiang, Fan; Kappes, John C; Sorscher, Eric J; Brodsky, Jeffrey L

Evaluating elexacaftor/tezacaftor/ivacaftor (ETI; Trikafta™) for treatment of patients with non-cystic fibrosis bronchiectasis (NCFBE): A clinical study protocol

评估 elexacaftor/tezacaftor/ivacaftor (ETI; Trikafta™) 治疗非囊性纤维化支气管扩张症 (NCFBE) 患者的疗效:一项临床研究方案

Swenson, Colin E; Hunt, William R; Manfredi, Candela; Beltran, Diana J; Hong, Jeong S; Davis, Brian R; Suzuki, Shingo; Barillá, Cristina; Rab, Andras; Chico, Cynthia; Dangerfield, Joy; Streby, Ashleigh; Barton, Erin; Cox, Elizabeth M; Stecenko, Arlene A; Westbrook, Adrianna; Kapolka, Rebecca; Sorscher, Eric J

Generation of Region-specific Airway Basal Stem Cells from Human Pluripotent Stem Cells via Regulation of BMP-NOGGIN Axis

通过调控BMP-NOGGIN轴,从人多能干细胞生成区域特异性气道基底干细胞

Suzuki, Shingo; Acosta Sandoval, Nicole V; Doddipalli, Shnutez; Hassan, Dalia M; Barillà, Cristina; Rab, Andras; Huang, Mo-Fan; Avila, John M; Tabak, Barbara; Lu, Junjie; Derebery, Bryan C; Garay, Maria Gacha; Winkler, Samantha L; Ponnaluri, Sadhana Srinagasai; Forcioli-Conti, Nicolas; Rea-Moreno, Martha; Chen, Ya-Wen; Kim, Jinho; Lee, Ciaran M; Nakayama, Naoki; Li, Wenbo; Mahoney, John E; Lee, Dung-Fang; Sorscher, Eric J; Chen, Jichao; Davis, Brian R; Huang, Sarah X

Mutation accumulation in H. sapiens F508del CFTR countermands dN/dS type genomic analysis

人类F508del CFTR突变积累与dN/dS型基因组分析相悖

Hong, Jeong S; Tindall, Janice M; Tindall, Samuel R; Sorscher, Eric J

Relationships between genomic dissipation and de novo SNP evolution

基因组耗散与从头SNP进化之间的关系

Plyler, Zackery E; McAtee, Christopher W; Hill, Aubrey E; Crowley, Michael R; Tindall, Janice M; Tindall, Samuel R; Joshi, Disha; Sorscher, Eric J

Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity

囊性纤维化跨膜传导调节因子影响SARS-CoV-2感染和COVID-19疾病严重程度的机制

Tedbury, Philip R; Manfredi, Candela; Degenhardt, Frauke; Conway, Joseph; Horwath, Michael C; McCracken, Courtney; Sorscher, Adam J; Moreau, Sandy; Wright, Christine; Edwards, Carolina; Brewer, Jo; Guarner, Jeannette; de Wit, Emmie; Williamson, Brandi N; Suthar, Mehul S; Ong, Yee T; Roback, John D; Alter, David N; Holter, Jan C; Karlsen, Tom H; Sacchi, Nicoletta; Romero-Gómez, Manuel; Invernizzi, Pietro; Fernández, Javier; Buti, Maria; Albillos, Agustin; Julià, Antonio; Valenti, Luca; Asselta, Rosanna; Banales, Jesus M; Bujanda, Luis; de Cid, Rafael; Franke, André; Sarafianos, Stefan G; Hong, Jeong S; Sorscher, Eric J; Ehrhardt, Annette

A Novel 7H-[1,2,4]Triazolo[3,4-b]thiadiazine-based Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Directed toward Treatment of Cystic Fibrosis

一种新型的基于7H-[1,2,4]三唑并[3,4-b]噻二嗪的囊性纤维化跨膜电导调节增强剂,用于治疗囊性纤维化

Rab, Andras; Yang, Xun; Tracy, William F; Hong, Jeong S; Joshi, Disha; Manfredi, Candela; Ponnaluri, Sadhana S; Kolykhalov, Alexander A; Qui, Min; Fu, Haian; Du, Yuhong; Davies, Huw M L; Sorscher, Eric J

Evaluating antitumor activity of Escherichia coli purine nucleoside phosphorylase against head and neck patient-derived xenografts

评价大肠杆菌嘌呤核苷磷酸化酶对头颈部患者来源异种移植瘤的抗肿瘤活性

Rab, Regina; Ehrhardt, Annette; Achyut, Bhagelu R; Joshi, Disha; Gilbert-Ross, Melissa; Huang, Chunzi; Floyd, Katharine; Borovjagin, Anton V; Parker, William B; Sorscher, Eric J; Hong, Jeong S