日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intrastriatal injection of alpha-synuclein preformed fibrils to rats results in L-DOPA reversible sensorimotor impairments and alterations in non-motor function.

向大鼠纹状体内注射α-突触核蛋白预成型原纤维会导致左旋多巴可逆的感觉运动障碍和非运动功能改变

Fleming Sheila M, Scott Sophia, Hamad Edward J, Herman Danielle E, Holden John G, Yan Lily, Linning-Duffy Katrina, Kemp Christopher J, Patterson Joseph R, Miller Kathryn M, Kubik Michael, Kuhn Nathan, Stoll Anna C, Duffy Megan F, Steece-Collier Kathy, Cole-Strauss Allyson, Lipton Jack W, Luk Kelvin C, Sortwell Caryl E

Downregulation of striatal Ca(V)1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

纹状体Ca(V)1.3的下调抑制了老年帕金森病雄性和雌性大鼠左旋多巴诱导的运动障碍的加重。

Caulfield, Margaret E; Vander Werp, Molly J; Stancati, Jennifer A; Collier, Timothy J; Sortwell, Caryl E; Sandoval, Ivette M; Manfredsson, Fredric P; Steece-Collier, Kathy

Quinpirole inhibits levodopa-induced dyskinesias at structural and behavioral levels: Efficacy negated by co-administration of isradipine

喹吡罗在结构和行为层面抑制左旋多巴诱发的运动障碍:与伊拉地平合用会抵消其疗效。

Collier, Timothy J; Begg, Lauren; Stancati, Jennifer A; Mercado, Natosha M; Sellnow, Rhyomi C; Sandoval, Ivette M; Sortwell, Caryl E; Steece-Collier, Kathy

Behavioral phenotyping of a rat model of the BDNF Val66Met polymorphism reveals selective impairment of fear memory

对BDNF Val66Met多态性大鼠模型的行为表型分析揭示了恐惧记忆的选择性损伤

Jaehne, Emily J; Kent, Jessica N; Antolasic, Emily J; Wright, Bradley J; Spiers, Jereme G; Creutzberg, Kerstin C; De Rosa, Federico; Riva, Marco A; Sortwell, Caryl E; Collier, Timothy J; van den Buuse, Maarten

Leveraging the preformed fibril model to distinguish between alpha-synuclein inclusion- and nigrostriatal degeneration-associated immunogenicity

利用预成型纤维模型区分α-突触核蛋白包涵体和黑质纹状体变性相关的免疫原性

Stoll, Anna C; Sortwell, Caryl E

BDNF rs6265 Genotype Influences Outcomes of Pharmacotherapy and Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease

BDNF rs6265基因型影响早期帕金森病药物治疗和丘脑底核深部脑刺激的疗效

Sortwell, Caryl E; Hacker, Mallory L; Fischer, David Luke; Konrad, Peter E; Davis, Thomas L; Neimat, Joseph S; Wang, Lily; Song, Yanna; Mattingly, Zach R; Cole-Strauss, Allyson; Lipton, Jack W; Charles, P David

BDNF rs10501087, rs1491850 and rs11030094 polymorphisms associated with delayed progression in early-stage Parkinson's disease

BDNF rs10501087、rs1491850 和 rs11030094 多态性与早期帕金森病进展延迟相关

Fischer, D Luke; Auinger, Peggy; Goudreau, John L; Paumier, Katrina L; Cole-Strauss, Allyson; Kemp, Christopher J; Lipton, Jack W; Sortwell, Caryl E

Synucleinopathy-associated pathogenesis in Parkinson's disease and the potential for brain-derived neurotrophic factor

帕金森病中突触核蛋白病相关的发病机制以及脑源性神经营养因子的潜在作用

Miller, Kathryn M; Mercado, Natosha M; Sortwell, Caryl E

Next-Generation Diamond Electrodes for Neurochemical Sensing: Challenges and Opportunities

用于神经化学传感的下一代金刚石电极:挑战与机遇

Purcell, Erin K; Becker, Michael F; Guo, Yue; Hara, Seth A; Ludwig, Kip A; McKinney, Collin J; Monroe, Elizabeth M; Rechenberg, Robert; Rusinek, Cory A; Saxena, Akash; Siegenthaler, James R; Sortwell, Caryl E; Thompson, Cort H; Trevathan, James K; Witt, Suzanne; Li, Wen

Stereotaxic Intracranial Delivery of Chemicals, Proteins or Viral Vectors to Study Parkinson's Disease

利用立体定向颅内递送化学物质、蛋白质或病毒载体研究帕金森病

Landeck, Natalie; Conti Mazza, Melissa; Duffy, Megan; Bishop, Christopher; Sortwell, Caryl E; Cookson, Mark R