日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A CRISPR-Cas13d cancer therapeutic enables selective elimination of uveal melanoma

一种 CRISPR-Cas13d 癌症疗法能够选择性地消除葡萄膜黑色素瘤

Stauber, Daniel; Sosnick, Lucas; Ma, Yitong; Pimcharoen, Sopida; Lawanprasert, Atip; Murthy, Niren; Myung, David; Qi, Lei S

Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs

全转录组范围内的mRNP凝聚先于应激颗粒的形成,并且排除了新的mRNA。

Glauninger, Hendrik; Bard, Jared A M; Wong Hickernell, Caitlin J; Velez, Karen M; Airoldi, Edo M; Li, Weihan; Singer, Robert H; Paul, Sneha; Fei, Jingyi; Sosnick, Tobin R; Wallace, Edward W J; Drummond, D Allan

Structural Mechanism of Prestin-Membrane Mechanotransduction

Prestin-膜机械转导的结构机制

Bavi, Navid; Haller, Patrick R; Homma, Kazuaki; Lin, Xiaoxuan; Milewski, Wieslawa; Zhao, Minglei; Sosnick, Tobin; Perozo, Eduardo

CRISPR-Cas13d-Mediated Targeting of a Context-Specific Essential Gene Enables Selective Elimination of Uveal Melanoma

利用 CRISPR-Cas13d 介导的靶向特定背景必需基因可选择性消除葡萄膜黑色素瘤

Stauber, Daniel; Sosnick, Lucas; Ma, Yitong; Pimcharoen, Sopida; Lawanprasert, Atip; Murthy, Niren; Myung, David; Qi, Lei Stanley

Temperature-dependent fold-switching mechanism of the circadian clock protein KaiB

昼夜节律时钟蛋白KaiB的温度依赖性折叠转换机制

Zhang, Ning; Sood, Damini; Guo, Spencer C; Chen, Nanhao; Antoszewski, Adam; Marianchuk, Tegan; Dey, Supratim; Xiao, Yunxian; Hong, Lu; Peng, Xiangda; Baxa, Michael; Partch, Carrie; Wang, Lee-Ping; Sosnick, Tobin R; Dinner, Aaron R; LiWang, Andy

Decoding cocaine-induced proteomic adaptations in the mouse nucleus accumbens

解码可卡因诱导的小鼠伏隔核蛋白质组学适应

Mews, Philipp; Sosnick, Lucas; Gurung, Ashik; Sidoli, Simone; Nestler, Eric J

How hydrophobicity, side chains, and salt affect the dimensions of disordered proteins

疏水性、侧链和盐如何影响无序蛋白的尺寸

Baxa, Michael C; Lin, Xiaoxuan; Mukinay, Cedrick D; Chakravarthy, Srinivas; Sachleben, Joseph R; Antilla, Sarah; Hartrampf, Nina; Riback, Joshua A; Gagnon, Isabelle A; Pentelute, Bradley L; Clark, Patricia L; Sosnick, Tobin R

Transcriptome-wide mRNA condensation precedes stress granule formation and excludes stress-induced transcripts

转录组范围内的 mRNA 凝聚先于应激颗粒形成,并排除应激诱导的转录本

Hendrik Glauninger, Jared A M Bard, Caitlin J Wong Hickernell, Edo M Airoldi, Weihan Li, Robert H Singer, Sneha Paul, Jingyi Fei, Tobin R Sosnick, Edward W J Wallace, D Allan Drummond

HDX-MS finds that partial unfolding with sequential domain activation controls condensation of a cellular stress marker

HDX-MS 发现,部分展开和连续域激活可控制细胞应激标记物的凝聚

Ruofan Chen, Hendrik Glauninger, Darren N Kahan, Julia Shangguan, Joseph R Sachleben, Joshua A Riback, D Allan Drummond, Tobin R Sosnick

AlphaFold developers Demis Hassabis and John Jumper share the 2023 Albert Lasker Basic Medical Research Award

AlphaFold 的开发者 Demis Hassabis 和 John Jumper 共同荣获 2023 年阿尔伯特·拉斯克基础医学研究奖

Sosnick, Tobin R