日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mitochondrial fission produces a Warburg effect via the oxidative inhibition of prolyl hydroxylase domain-2

线粒体分裂通过氧化抑制脯氨酰羟化酶结构域-2产生瓦博格效应。

Sun, Xutong; Yegambaram, Manivannan; Lu, Qing; Garcia Flores, Alejandro E; Pokharel, Marissa D; Soto, Jamie; Aggarwal, Saurabh; Wang, Ting; Fineman, Jeffrey R; Black, Stephen M

Mechanotransductive stabilization of HIF-1α is inhibited by mitochondrial antioxidant therapy in the setting of pulmonary overcirculation.

在肺循环过度的情况下,线粒体抗氧化疗法会抑制 HIF-1α 的机械转导稳定作用

Boehme Jason T, Datar Sanjeev A, Sun Xutong, Gong Wenhui, Lu Qing, Soto Jamie, Smith Michael A, Garcia-Flores Alejandro E, Raff Gary W, Wang Ting, Maltepe Emin, Black Stephen M, Fineman Jeffrey R

c-Myc promotes metabolic reprogramming in pulmonary hypertension via the stimulation of glutaminolysis and the reductive tricarboxylic acid cycle

c-Myc通过刺激谷氨酰胺分解和还原性三羧酸循环,促进肺动脉高压中的代谢重编程。

Yegambaram, Manivannan; Sun, Xutong; Lu, Qing; Flores, Alejandro Garcia; Zemskova, Marina; Soto, Jamie; Rauckhorst, Adam; Maltepe, Emin; Wang, Ting; Fineman, Jeffrey R; Black, Stephen M

Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities of electron transport chain complexes I and III

线粒体过度融合通过改变电子传递链复合物 I 和 III 的活性,诱导肺内皮细胞代谢重塑。

Yegambaram, Manivannan; Sun, Xutong; Lu, Qing; Jin, Yan; Ornatowski, Wojciech; Soto, Jamie; Aggarwal, Saurabh; Wang, Ting; Tieu, Kim; Gu, Haiwei; Fineman, Jeffrey R; Black, Stephen M

Isotopic and microbotanical insights into Iron Age agricultural reliance in the Central African rainforest

同位素和微植物学洞察中非雨林铁器时代农业的依赖

Madeleine Bleasdale, Hans-Peter Wotzka, Barbara Eichhorn, Julio Mercader, Amy Styring, Jana Zech, María Soto, Jamie Inwood, Siobhán Clarke, Sara Marzo, Bianca Fiedler, Veerle Linseele, Nicole Boivin, Patrick Roberts2

Comparison of the Effects of High-Fat Diet on Energy Flux in Mice Using Two Multiplexed Metabolic Phenotyping Systems

利用两种多重代谢表型分析系统比较高脂饮食对小鼠能量通量的影响

Soto, Jamie E; Burnett, Colin M L; Ten Eyck, Patrick; Abel, E Dale; Grobe, Justin L

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

GLUT1减少会加剧阿尔茨海默病血管神经元功能障碍和退行性变。

Winkler, Ethan A; Nishida, Yoichiro; Sagare, Abhay P; Rege, Sanket V; Bell, Robert D; Perlmutter, David; Sengillo, Jesse D; Hillman, Sara; Kong, Pan; Nelson, Amy R; Sullivan, John S; Zhao, Zhen; Meiselman, Herbert J; Wendy, Rosalinda B; Soto, Jamie; Abel, E Dale; Makshanoff, Jacob; Zuniga, Edward; De Vivo, Darryl C; Zlokovic, Berislav V

Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome

在代谢综合征小鼠模型中,抗氧化剂治疗可使线粒体能量代谢和心肌胰岛素敏感性恢复正常,且该作用独立于全身代谢稳态的变化。

Ilkun, Olesya; Wilde, Nicole; Tuinei, Joseph; Pires, Karla M P; Zhu, Yi; Bugger, Heiko; Soto, Jamie; Wayment, Benjamin; Olsen, Curtis; Litwin, Sheldon E; Abel, E Dale

GLUT1 deficiency in cardiomyocytes does not accelerate the transition from compensated hypertrophy to heart failure

心肌细胞中GLUT1缺乏并不会加速代偿性肥大向心力衰竭的转变。

Pereira, Renata O; Wende, Adam R; Olsen, Curtis; Soto, Jamie; Rawlings, Tenley; Zhu, Yi; Riehle, Christian; Abel, E Dale

Solid phase synthesis of mitochondrial triphenylphosphonium-vitamin E metabolite using a lysine linker for reversal of oxidative stress

利用赖氨酸连接子固相合成线粒体三苯基膦-维生素E代谢物以逆转氧化应激

Mossalam, Mohanad; Soto, Jamie; Lim, Carol S; Abel, E Dale