日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Updated Overall Survival and Long-Term Safety With Ripretinib Versus Sunitinib in Patients With GI Stromal Tumor: Final Overall Survival Analysis From INTRIGUE

INTRIGUE 研究的最终总生存期分析:瑞普替尼与舒尼替尼治疗胃肠道间质瘤患者的总体生存期和长期安全性更新

Heinrich, Michael C; Blay, Jean-Yves; Gelderblom, Hans; George, Suzanne; Schöffski, Patrick; von Mehren, Margaret; Zalcberg, John R; Jones, Robin L; Kang, Yoon-Koo; Razak, Albiruni Abdul; Trent, Jonathan; Attia, Steven; Le Cesne, Axel; Boye, Kjetil; Goldstein, David; Sánchez, César; Siontis, Brittany L; Cox, Paulina; Davis, Erika; Sherman, Matthew L; Ruiz-Soto, Rodrigo; Bauer, Sebastian

Active bacterial baths in droplets.

液滴中活性细菌浴

Villalobos-Concha Cristian, Liu Zhengyang, Ramos Gabriel, Goral Martyna, Lindner Anke, López-León Teresa, Clément Eric, Soto Rodrigo, Cordero María Luisa

Pharmacokinetics and Safety of Ripretinib in Participants with Hepatic Impairment: A Phase 1 Study

瑞普替尼在肝功能受损患者中的药代动力学和安全性:一项 I 期研究

Papinska, Anna; Viswanathan, Lakshmi; Lu, Qiang; Abane, Farida; Psoinos, Charles; Ruiz-Soto, Rodrigo

Do humanitarian missions impede the progress of pediatric cardiac surgical programs in developing and under-served nations?

人道主义援助任务是否会阻碍发展中国家和医疗资源匮乏国家儿科心脏外科手术项目的进展?

Karl, Tom Roland; Soto, Rodrigo; Raylman, Rob

Vimseltinib versus placebo for tenosynovial giant cell tumour (MOTION): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

Vimseltinib 与安慰剂治疗腱鞘巨细胞瘤 (MOTION):一项多中心、随机、双盲、安慰剂对照的 3 期试验

Gelderblom, Hans; Bhadri, Vivek; Stacchiotti, Silvia; Bauer, Sebastian; Wagner, Andrew J; van de Sande, Michiel; Bernthal, Nicholas M; López Pousa, Antonio; Razak, Albiruni Abdul; Italiano, Antoine; Ahmed, Mahbubl; Le Cesne, Axel; Tinoco, Gabriel; Boye, Kjetil; Martín-Broto, Javier; Palmerini, Emanuela; Tafuto, Salvatore; Pratap, Sarah; Powers, Benjamin C; Reichardt, Peter; Casado Herráez, Antonio; Rutkowski, Piotr; Tait, Christopher; Zarins, Fiona; Harrow, Brooke; Sharma, Maitreyi G; Ruiz-Soto, Rodrigo; Sherman, Matthew L; Blay, Jean-Yves; Tap, William D

Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial

瑞普替尼与舒尼替尼治疗胃肠道间质瘤:INTRIGUE III期试验的ctDNA生物标志物分析

Heinrich, Michael C; Jones, Robin L; George, Suzanne; Gelderblom, Hans; Schöffski, Patrick; von Mehren, Margaret; Zalcberg, John R; Kang, Yoon-Koo; Razak, Albiruni Abdul; Trent, Jonathan; Attia, Steven; Le Cesne, Axel; Siontis, Brittany L; Goldstein, David; Boye, Kjetil; Sanchez, Cesar; Steeghs, Neeltje; Rutkowski, Piotr; Druta, Mihaela; Serrano, César; Somaiah, Neeta; Chi, Ping; Reichmann, William; Sprott, Kam; Achour, Haroun; Sherman, Matthew L; Ruiz-Soto, Rodrigo; Blay, Jean-Yves; Bauer, Sebastian

CSF1R Inhibition in Patients with Advanced Solid Tumors or Tenosynovial Giant Cell Tumor: A Phase I Study of Vimseltinib

CSF1R抑制剂治疗晚期实体瘤或腱鞘巨细胞瘤患者:Vimseltinib的I期研究

Gelderblom, Hans; Razak, Albiruni A; Taylor, Matthew H; Bauer, Todd M; Wilky, Breelyn; Martin-Broto, Javier; Gonzalez, Alejandro F; Rutkowski, Piotr; Szostakowski, Bartlomiej; Alcindor, Thierry; Saleh, Ramy; Genta, Sofia; Stacchiotti, Silvia; van de Sande, Michiel; Wagner, Andrew J; Bernthal, Nicholas; Davis, Lara E; Vuky, Jacqueline; Tait, Christopher; Matin, Bahar; Narasimhan, Supraja; Sharma, Maitreyi G; Ruiz-Soto, Rodrigo; Sherman, Matthew L; Tap, William D

Adaptation of the protein misfolding cyclic amplification (PMCA) technique for the screening of anti-prion compounds

采用蛋白质错误折叠循环扩增 (PMCA) 技术筛选抗朊病毒化合物

Katherine Do, Rebeca Benavente, Celso S G Catumbela, Uffaf Khan, Carlos Kramm, Claudio Soto, Rodrigo Morales

The INSIGHT study: a randomized, Phase III study of ripretinib versus sunitinib for advanced gastrointestinal stromal tumor with KIT exon 11 + 17/18 mutations

INSIGHT 研究:一项随机、III 期研究,比较瑞普替尼与舒尼替尼治疗伴有 KIT 外显子 11 + 17/18 突变的晚期胃肠道间质瘤的疗效。

George, Suzanne; Blay, Jean-Yves; Chi, Ping; Jones, Robin L; Serrano, César; Somaiah, Neeta; Gelderblom, Hans; Zalcberg, John R; Reichmann, William; Sprott, Kam; Cox, Paulina; Sherman, Matthew L; Ruiz-Soto, Rodrigo; Heinrich, Michael C; Bauer, Sebastian

Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice

两种结构明确的 Aβ 多态性导致易感小鼠发生不同的病理变化

Ruben Gomez-Gutierrez, Ujjayini Ghosh, Wai-Ming Yau, Nazaret Gamez, Katherine Do, Carlos Kramm, Hamid Shirani, Laura Vegas-Gomez, Jonathan Schulz, Ines Moreno-Gonzalez, Antonia Gutierrez, K Peter R Nilsson, Robert Tycko, Claudio Soto, Rodrigo Morales